Compile Data Set for Download or QSAR
Report error Found 171 Enz. Inhib. hit(s) with all data for entry = 3268
LigandPNGBDBM396004(US10308660, Example 105)
Affinity DataIC50: 8nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM395996(US10308660, Example 97)
Affinity DataIC50: 9nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM396001(US10308660, Example 102)
Affinity DataIC50: 10nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM396023(US10308660, Example 124)
Affinity DataIC50: 10nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM396024(US10308660, Example 125)
Affinity DataIC50: 12nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM396025(US10308660, Example 126)
Affinity DataIC50: 12nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM395943(US10308660, Example 19)
Affinity DataIC50: 14nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM395966(US10308660, Example 42 | US12053470, Compound 33)
Affinity DataIC50: 14nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM396022(6-amino-2-((3S,4S)-4-amino-3-methyl-2-oxa-8-azaspi...)
Affinity DataIC50: 14nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM396026(US10308660, Example 127)
Affinity DataIC50: 14nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM396027(US10308660, Example 129 | US12053470, Compound 29)
Affinity DataIC50: 14nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM396028(US10308660, Example 130)
Affinity DataIC50: 14nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM396002(US10308660, Example 103)
Affinity DataIC50: 15nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM396019(US10308660, Example 120)
Affinity DataIC50: 15nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM396086(US10308660, Example 188)
Affinity DataIC50: 15nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM395983(US10308660, Example 60)
Affinity DataIC50: 16nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM396009(US10308660, Example 110)
Affinity DataIC50: 16nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM396029(US10308660, Example 131)
Affinity DataIC50: 16nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM396030(US10308660, Example 132)
Affinity DataIC50: 16nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM395944(US10308660, Example 20 | US12053470, Compound 30)
Affinity DataIC50: 17nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM395956(US10308660, Example 32)
Affinity DataIC50: 17nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM396031(US10308660, Example 133)
Affinity DataIC50: 17nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM395967(US10308660, Example 43)
Affinity DataIC50: 18nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM396011(US10308660, Example 112)
Affinity DataIC50: 19nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM396032(US10308660, Example 134)
Affinity DataIC50: 19nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM396033(US10308660, Example 135)
Affinity DataIC50: 19nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM395955(US10308660, Example 31 | US12053470, Compound 32)
Affinity DataIC50: 20nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM395989(US10308660, Example 66)
Affinity DataIC50: 20nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM396034(US10308660, Example 136)
Affinity DataIC50: 20nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM395926(6-amino-2-(4-(aminomethyl)-4-methylpiperidin-1-yl)...)
Affinity DataIC50: 21nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM396090(US10308660, Example 192)
Affinity DataIC50: 21nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM395940(US10308660, Example 16)
Affinity DataIC50: 22nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM396035(US10308660, Example 137)
Affinity DataIC50: 22nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM395942(US10308660, Example 18)
Affinity DataIC50: 23nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM395947(US10308660, Example 23)
Affinity DataIC50: 23nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM395994(US10308660, Example 95)
Affinity DataIC50: 23nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM395959(US10308660, Example 35)
Affinity DataIC50: 24nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM396036(US10308660, Example 138)
Affinity DataIC50: 24nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM395951(US10308660, Example 27)
Affinity DataIC50: 25nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM395985(US10308660, Example 62)
Affinity DataIC50: 25nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM396037(US10308660, Example 139)
Affinity DataIC50: 25nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM396038(US10308660, Example 140 | US12053470, Compound 36)
Affinity DataIC50: 25nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM396008(US10308660, Example 109)
Affinity DataIC50: 26nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM396039(US10308660, Example 141)
Affinity DataIC50: 26nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM396040(US10308660, Example 142)
Affinity DataIC50: 27nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM396089(US10308660, Example 191)
Affinity DataIC50: 27nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM395945(US10308660, Example 21)
Affinity DataIC50: 28nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM395952(US10308660, Example 28)
Affinity DataIC50: 28nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
Entry Details
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LigandPNGBDBM396041(US10308660, Example 143)
Affinity DataIC50: 28nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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LigandPNGBDBM395965(US10308660, Example 41)
Affinity DataIC50: 29nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
4/15/2020
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