Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 3262
TargetCyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395706(US10308648, Compound 101 | (+/−)-4-amino-N-(...)
Affinity DataIC50: 100nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies (Grand Island, N.Y.) using their commercially available Adapta kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395710(US10308648, Compound 105 | N-((1S,3R)-3-((5-chloro...)
Affinity DataIC50: 100nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies (Grand Island, N.Y.) using their commercially available Adapta kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395711(US10308648, Compound 106 | (1S,3R) N-(4-aminophen...)
Affinity DataIC50: 100nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies (Grand Island, N.Y.) using their commercially available Adapta kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395712(US10308648, Compound 107 | 4-amino-N-((1S,3R)-3-(5...)
Affinity DataIC50: 100nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies (Grand Island, N.Y.) using their commercially available Adapta kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395707(US10308648, Compound 102 | 4-amino-N-((1S,3R)-3-(5...)
Affinity DataIC50: 550nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies (Grand Island, N.Y.) using their commercially available Adapta kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395708(US10308648, Compound 103 | 4-amino-N-((1S,3R)-3-(5...)
Affinity DataIC50: 550nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies (Grand Island, N.Y.) using their commercially available Adapta kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395709(US10308648, Compound 104 | 4-amino-N-(5-(5-chloro-...)
Affinity DataIC50: 550nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies (Grand Island, N.Y.) using their commercially available Adapta kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395714(US10308648, Compound 109 | US10865206, Compound 10...)
Affinity DataIC50: 550nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies (Grand Island, N.Y.) using their commercially available Adapta kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395715(US10308648, Compound 110 | (+/−)-4-amino-N-(...)
Affinity DataIC50: 550nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies (Grand Island, N.Y.) using their commercially available Adapta kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395716(US10308648, Compound 111 | 4-amino-N-(1S,3R)-3-(5-...)
Affinity DataIC50: 550nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies (Grand Island, N.Y.) using their commercially available Adapta kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395717(US10308648, Compound 112 | 4-amino-N-((1S,3R)-3-(5...)
Affinity DataIC50: 550nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies (Grand Island, N.Y.) using their commercially available Adapta kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395718(US10308648, Compound 113 | N1-(4-(((1S,3R)-3-((5-c...)
Affinity DataIC50: 550nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies (Grand Island, N.Y.) using their commercially available Adapta kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395705(US10308648, Compound 100 | 4-amino-N-(3-(5-chloro-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies (Grand Island, N.Y.) using their commercially available Adapta kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395713(US10308648, Compound 108 | 4-amino-N-((1S,3R)-3-(5...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies (Grand Island, N.Y.) using their commercially available Adapta kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395719(US10308648, Compound 114 | N-((1S,3R)-3-(4-(1H-ind...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies (Grand Island, N.Y.) using their commercially available Adapta kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent