Compile Data Set for Download or QSAR
Report error Found 58 Enz. Inhib. hit(s) with all data for entry = 3128
LigandPNGBDBM392324(6-(4-(aminomethyl)-4-methylpiperidin-1-yl)-3-((2,3...)
Affinity DataIC50: 14nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392359(US10301278, Example 51)
Affinity DataIC50: 17nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392362(US10301278, Example 55)
Affinity DataIC50: 17.7nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392316(5-amino-3-(4-(aminomethyl)-4-methylpiperidin-1-yl)...)
Affinity DataIC50: 19nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392338(US10301278, Example 20)
Affinity DataIC50: 22nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392323(3-((2-amino-3-chloropyridin-4-yl)thio)-6-(4-(amino...)
Affinity DataIC50: 23nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392319(6-(4-amino-4-methylpiperidin-1-yl)-3-((2-chloro-4-...)
Affinity DataIC50: 23nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392320(6-(4-(aminomethyl)-4-methylpiperidin-1-yl)-3-((2-c...)
Affinity DataIC50: 26nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392315(6-(4-(aminomethyl)-4-methylpiperidin-1-yl)-3-((2-(...)
Affinity DataIC50: 29nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392340(US10301278, Example 22)
Affinity DataIC50: 44nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392339(US10301278, Example 21)
Affinity DataIC50: 46nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392342(US10301278, Example 24)
Affinity DataIC50: 49nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392341(US10301278, Example 23)
Affinity DataIC50: 51nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392314(6-(4-(aminomethyl)-4-(pyridin-3-yl)piperidin-1-yl)...)
Affinity DataIC50: 54nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392251(6-(4-amino-4-methylpiperidin-1-yl)-3-((2-chloro-3-...)
Affinity DataIC50: 56nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392358(US10301278, Example 50)
Affinity DataIC50: 59nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392009(6-(4-amino-4-methylpiperidin-1-yl)-3-((2-(trifluor...)
Affinity DataIC50: 59nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392322((S) and (R)-6-(4-(1-aminoethyl)-4-methylpiperidin-...)
Affinity DataIC50: 61nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392326((4-amino-1-(6-amino-5-((2,3-dichloropyridin-4-yl)t...)
Affinity DataIC50: 62nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392311(N-(3-((3-amino-5-(4-amino-4-methylpiperidin-1-yl)p...)
Affinity DataIC50: 62nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392349(US10301278, Example 31b)
Affinity DataIC50: 64nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392311(N-(3-((3-amino-5-(4-amino-4-methylpiperidin-1-yl)p...)
Affinity DataIC50: 66nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392347(US10301278, Example 30)
Affinity DataIC50: 66nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392344(US10301278, Example 26)
Affinity DataIC50: 67nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM38019(US10093646, Compound 1 | US10301278, Example 00003...)
Affinity DataIC50: 70nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392330(US10301278, Example 2)
Affinity DataIC50: 70nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392308(6-(4-amino-4-methylpiperidin-1-yl)-3-((3-azido-2-c...)
Affinity DataIC50: 71nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392345(US10301278, Example 27a)
Affinity DataIC50: 76nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392318(6-(4-amino-4-methylpiperidin-1-yl)-3-((3-chloropyr...)
Affinity DataIC50: 76nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392343(US10301278, Example 25)
Affinity DataIC50: 77nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392321(6-(4-(aminomethyl)-4-(thiazol-4-yl)piperidin-1-yl)...)
Affinity DataIC50: 79nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392352(US10301278, Example 37)
Affinity DataIC50: 82nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392311(N-(3-((3-amino-5-(4-amino-4-methylpiperidin-1-yl)p...)
Affinity DataIC50: 85nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392311(N-(3-((3-amino-5-(4-amino-4-methylpiperidin-1-yl)p...)
Affinity DataIC50: 94nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392324(6-(4-(aminomethyl)-4-methylpiperidin-1-yl)-3-((2,3...)
Affinity DataIC50: 100nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392317(5-amino-3-(4-(aminomethyl)-4-(pyridin-2-yl)piperid...)
Affinity DataIC50: 102nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392351(US10301278, Example 35)
Affinity DataIC50: 109nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392310(3-(4-amino-4-methylpiperidin-1-yl)-6-((2,3-dichlor...)
Affinity DataIC50: 143nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392361(US10301278, Example 54)
Affinity DataIC50: 170nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392356(US10301278, Example 48)
Affinity DataIC50: 177nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392309(N-(3-((3-amino-5-(4-amino-4-methylpiperidin-1-yl)p...)
Affinity DataIC50: 180nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392350(US10301278, Example 32)
Affinity DataIC50: 195nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392333(US10301278, Example 6)
Affinity DataIC50: 210nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392336(US10301278, Example 13)
Affinity DataIC50: 257nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392337(US10301278, Example 15)
Affinity DataIC50: 266nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392325(3-((3-amino-2-chlorophenyl)thio)-6-(4-(aminomethyl...)
Affinity DataIC50: 271nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392071(3-((3-amino-5-(4-amino-4-methylpiperidin-1-yl)pyra...)
Affinity DataIC50: 307nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392360(US10301278, Example 53)
Affinity DataIC50: 315nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392353(US10301278, Example 45)
Affinity DataIC50: 351nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
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LigandPNGBDBM392346(US10301278, Example 27b)
Affinity DataIC50: 377nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
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Date in BDB:
3/25/2020
Entry Details
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