Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 3106
TargetReceptor activity-modifying protein 1(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM391716(US10300056, Example 1 | N-[(2R)-3-(7-methyl-1H- | ...)
Affinity DataKi:  0.0200nMAssay Description:Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
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TargetReceptor activity-modifying protein 1(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM391727(US10300056, Example 12 | N-[(2R)-1-({(2S)-3-{1-[2-...)
Affinity DataKi:  0.0250nMAssay Description:Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
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TargetReceptor activity-modifying protein 1(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM391726(US10300056, Example 11 | N-[(2R)-3-(7-methyl-1H- |...)
Affinity DataKi:  0.0320nMAssay Description:Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
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TargetReceptor activity-modifying protein 1(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM391719(US10300056, Example 4 | N-[(2R)-3-(7-methyl-1H- | ...)
Affinity DataKi:  0.0400nMAssay Description:Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
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TargetReceptor activity-modifying protein 1(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM391722(US10300056, Example 7 | N-[(2R)-1-({(2S)-3-(1- | U...)
Affinity DataKi:  0.0400nMAssay Description:Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
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TargetReceptor activity-modifying protein 1(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM391723(US10300056, Example 8 | 3,5-dibromo-Nalpha-{[4-(2-...)
Affinity DataKi:  0.0400nMAssay Description:Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
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TargetReceptor activity-modifying protein 1(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM391720(US10300056, Example 5 | 3,5-dibromo-Nalpha-{[4-(2-...)
Affinity DataKi:  0.0630nMAssay Description:Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
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TargetReceptor activity-modifying protein 1(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM391725(US10300056, Example 10 | N-[(2R)-3-(7-methyl-1H- |...)
Affinity DataKi:  0.0630nMAssay Description:Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
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TargetReceptor activity-modifying protein 1(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM391718(US10300056, Example 3 | N-[(2R)-3-(7-methyl-1H- | ...)
Affinity DataKi:  0.0790nMAssay Description:Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
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TargetReceptor activity-modifying protein 1(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM391724(US10300056, Example 9 | 3,5-dibromo-Nalpha-{[4-(2-...)
Affinity DataKi:  0.0790nMAssay Description:Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
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TargetReceptor activity-modifying protein 1(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM391729(US10300056, Example 14 | 3,5-dibromo-Nalpha-[(2'-o...)
Affinity DataKi:  0.0790nMAssay Description:Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
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TargetReceptor activity-modifying protein 1(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM391717(US10300056, Example 2 | tert-butyl 4-{(2S)-2- | US...)
Affinity DataKi:  0.100nMAssay Description:Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
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TargetReceptor activity-modifying protein 1(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM391721(US10300056, Example 6 | N-[(2R)-3-(7-methyl-1H- | ...)
Affinity DataKi:  0.100nMAssay Description:Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
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TargetReceptor activity-modifying protein 1(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM391728(US10300056, Example 13 | 3-(4-{(2S)-2-{[(2R)-3-(7-...)
Affinity DataKi:  0.100nMAssay Description:Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
Go to US Patent