Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 2877
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383948(2-[2-[[3-chloro-5- (trifluoromethyl)pyrazol-1- yl]...)
Affinity DataEC50:  178nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM50205852(CHEMBL3976578 | US10280165, Example 38)
Affinity DataEC50:  39nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383940((1S,2S)-2-[2-[[5-chloro-3- (trifluoromethyl)pyrazo...)
Affinity DataEC50:  951nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383941((1R,2R)-2-[2-[[5-chloro-3- (trifluoromethyl)pyrazo...)
Affinity DataEC50:  24nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383942((1S,2S)-2-[2-[[5-chloro-3- (trifluoromethyl)pyrazo...)
Affinity DataEC50:  2.90E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383943((1S,2S)-2-[7-chloro-2-[[5-chloro-3- (trifluorometh...)
Affinity DataEC50:  1.06E+4nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383944(2-[2-[[3-chloro-5- (trifluoromethyl)pyrazol-1- yl]...)
Affinity DataEC50:  269nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383945(2-[2-[[3-chloro-5- (trifluoromethyl)pyrazol-1- yl]...)
Affinity DataEC50:  227nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM50205850(CHEMBL3970291 | US10280165, Example 45)
Affinity DataEC50:  21nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383947((1S,2S)-2-[2-[[5-chloro-3- (trifluoromethyl)pyrazo...)
Affinity DataEC50:  3.22E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383938(2-[[5-chloro-3- (trifluoromethyl)pyrazol-1- yl]met...)
Affinity DataEC50:  126nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383949(2-[[5-chloro-3- (trifluoromethyl)pyrazol-1- yl]met...)
Affinity DataEC50:  3.24E+4nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383950(6-acetyl-2-[[5-chloro-3- (trifluoromethyl)pyrazol-...)
Affinity DataEC50:  1.23E+4nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383951(6-acetyl-2-[[5-chloro-3- (trifluoromethyl)pyrazol-...)
Affinity DataEC50:  7.70E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383952(6-acetyl-2-[[3-chloro-5- (trifluoromethyl)pyrazol-...)
Affinity DataEC50:  9.10E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM50205853(CHEMBL3968067 | US10280165, Example 52)
Affinity DataEC50:  79nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383954(6-chloro-2-[[5-chloro-3- (trifluoromethyl)pyrazol-...)
Affinity DataEC50:  2.47E+4nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383955(2-((3,5-dichloro-1H-pyrazol-1- yl)methyl)-7-methox...)
Affinity DataEC50:  102nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM50205848(CHEMBL3948381 | US10280165, Example 56)
Affinity DataEC50:  123nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383957((1R,2R)-2-(2-((3,5-dichloro-1H- pyrazol-1-yl)methy...)
Affinity DataEC50:  222nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383928(2-[(N-ethyl-4-fluoro-anilino)methyl]- 4-oxo-pyrido...)
Affinity DataEC50:  5.80E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383919(2-[(N-ethylanilino)methyl]-7-methyl- pyrido[1,2-a]...)
Affinity DataEC50:  1.11E+4nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383920(2-[(N-ethyl-4-fluoro-anilino)methyl]- 7-methyl-pyr...)
Affinity DataEC50:  5.20E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383921(6-ethyl-2-[(N-ethyl-4-fluoro- anilino)methyl]pyrid...)
Affinity DataEC50:  6.40E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383922(6-ethyl-2-[(N- ethylanilino)methyl]pyrido[1,2- a]p...)
Affinity DataEC50:  1.15E+4nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383923(2-[(N-ethyl-4-fluoro-anilino)methyl]- 6-methyl-pyr...)
Affinity DataEC50:  1.36E+4nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383924(2-[(N-ethyl-fluoro-anilino)methyl]- 6-methoxy-pyri...)
Affinity DataEC50:  4.40E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383925(6-ethoxy-2-[(N-ethyl-4-fluoro- anilino)methyl]pyri...)
Affinity DataEC50:  5.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383926(2-[(N-ethyl-4-fluoro-anilino)methyl]- 6-pyrimidin-...)
Affinity DataEC50:  6.40E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383927(2-[(N-ethyl-4-fluoro-anilino)methyl]- 6-(2-furyl)p...)
Affinity DataEC50:  371nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM50205849(CHEMBL3938522 | US10280165, Example 1)
Affinity DataEC50:  36.8nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383929(6-bromo-2-[(N-ethyl-4-fluoro- anilino)methyl]pyrid...)
Affinity DataEC50:  6.20E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383930(N-ethyl-2-[(4- fluorophenoxy)methyl]-7-methyl-4- o...)
Affinity DataEC50:  3.60E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383931(2-[[5-cyclopropyl-3- (trifluoromethyl)pyrazol-1- y...)
Affinity DataEC50:  4.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383932(2-[[3-cyclopropyl-5- (trifluoromethyl)pyrazol-1- y...)
Affinity DataEC50:  1.62E+4nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383933(2-[[5-cyclopropyl-3- (trifluoromethyl)pyrazol-1- y...)
Affinity DataEC50:  7.40E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383934(2-[(N-ethyl-4-fluoro-anilino)methyl]- N,7-dimethyl...)
Affinity DataEC50:  2.70E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383935(2-[[5-cyclopropyl-3- (trifluoromethyl)pyrazol-1- y...)
Affinity DataEC50:  5.90E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM383936((1S,2S)-2-[2-[[5-chloro-3- (trifluoromethyl)pyrazo...)
Affinity DataEC50:  2.55E+4nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Genentech

US Patent
LigandPNGBDBM50206009(CHEMBL3983039 | US10280165, Example 35)
Affinity DataEC50:  77nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)