Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 2318
TargetApoptosis regulator Bcl-2(Human)
University of Michigan

US Patent
LigandPNGBDBM361573(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((6-(4...)
Affinity DataIC50: 0.760nMAssay Description:Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respectively, were used as the fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
University of Michigan

US Patent
LigandPNGBDBM361574(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((6-(4...)
Affinity DataIC50: 1.20nMAssay Description:Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respectively, were used as the fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
University of Michigan

US Patent
LigandPNGBDBM361590(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4- ((6-(...)
Affinity DataIC50: 1.30nMAssay Description:Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respectively, were used as the fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
University of Michigan

US Patent
LigandPNGBDBM361584((R)-N-((4-(((1,4-dioxan-2-yl)methyl)amino)-3- nitr...)
Affinity DataIC50: 1.30nMAssay Description:Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respectively, were used as the fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
University of Michigan

US Patent
LigandPNGBDBM361572((R)-N-((4-(((1,4-dioxan-2-yl)methyl)amino)-3- nitr...)
Affinity DataIC50: 1.40nMAssay Description:Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respectively, were used as the fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
University of Michigan

US Patent
LigandPNGBDBM361592(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4- ((6-(...)
Affinity DataIC50: 1.40nMAssay Description:Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respectively, were used as the fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
University of Michigan

US Patent
LigandPNGBDBM361589(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4- ((6-(...)
Affinity DataIC50: 1.60nMAssay Description:Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respectively, were used as the fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
University of Michigan

US Patent
LigandPNGBDBM361580(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(1-((6-(4...)
Affinity DataIC50: 1.90nMAssay Description:Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respectively, were used as the fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
University of Michigan

US Patent
LigandPNGBDBM361577((S)-N-((4-(((1,4-dioxan-2-yl)methyl)amino)-3- nitr...)
Affinity DataIC50: 2nMAssay Description:Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respectively, were used as the fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
University of Michigan

US Patent
LigandPNGBDBM361587(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4- ((6-(...)
Affinity DataIC50: 2.10nMAssay Description:Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respectively, were used as the fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
University of Michigan

US Patent
LigandPNGBDBM361576((R)-N-((4-(((1,4-dioxan-2-yl)methyl)amino)-3- nitr...)
Affinity DataIC50: 2.10nMAssay Description:Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respectively, were used as the fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
University of Michigan

US Patent
LigandPNGBDBM361588(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4- ((6-(...)
Affinity DataIC50: 2.10nMAssay Description:Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respectively, were used as the fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
University of Michigan

US Patent
LigandPNGBDBM361578(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(1-((6-(4...)
Affinity DataIC50: 2.40nMAssay Description:Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respectively, were used as the fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
University of Michigan

US Patent
LigandPNGBDBM361579((R)-N-((4-(((1,4-dioxan-2-yl)methyl)amino)-3- nitr...)
Affinity DataIC50: 2.40nMAssay Description:Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respectively, were used as the fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
University of Michigan

US Patent
LigandPNGBDBM361591(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4- ((6-(...)
Affinity DataIC50: 2.40nMAssay Description:Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respectively, were used as the fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
University of Michigan

US Patent
LigandPNGBDBM361593(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4- ((6-(...)
Affinity DataIC50: 2.70nMAssay Description:Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respectively, were used as the fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
University of Michigan

US Patent
LigandPNGBDBM361575(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((6-(4...)
Affinity DataIC50: 3.10nMAssay Description:Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respectively, were used as the fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
University of Michigan

US Patent
LigandPNGBDBM361581(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((6-(4...)
Affinity DataIC50: 3.30nMAssay Description:Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respectively, were used as the fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
University of Michigan

US Patent
LigandPNGBDBM361585(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4- ((6-(...)
Affinity DataIC50: 3.80nMAssay Description:Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respectively, were used as the fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
University of Michigan

US Patent
LigandPNGBDBM361589(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4- ((6-(...)
In Depth
Date in BDB:
10/27/2019
Entry Details
Go to US Patent

TargetApoptosis regulator Bcl-2(Human)
University of Michigan

US Patent
LigandPNGBDBM361583(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(1-((6-(4...)
Affinity DataIC50: 4.40nMAssay Description:Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respectively, were used as the fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
Go to US Patent

TargetApoptosis regulator Bcl-2(Human)
University of Michigan

US Patent
LigandPNGBDBM361586(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4- ((6-(...)
Affinity DataIC50: 5nMAssay Description:Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respectively, were used as the fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
Go to US Patent

TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
University of Michigan

US Patent
LigandPNGBDBM361577((S)-N-((4-(((1,4-dioxan-2-yl)methyl)amino)-3- nitr...)
Affinity DataIC50: 5.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
Go to US Patent

TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
University of Michigan

US Patent
LigandPNGBDBM361579((R)-N-((4-(((1,4-dioxan-2-yl)methyl)amino)-3- nitr...)
Affinity DataIC50: 6.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
University of Michigan

US Patent
LigandPNGBDBM361590(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4- ((6-(...)
Affinity DataIC50: 7.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
University of Michigan

US Patent
LigandPNGBDBM361575(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((6-(4...)
Affinity DataIC50: 8.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
University of Michigan

US Patent
LigandPNGBDBM361591(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4- ((6-(...)
Affinity DataIC50: 8.70nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
University of Michigan

US Patent
LigandPNGBDBM361572((R)-N-((4-(((1,4-dioxan-2-yl)methyl)amino)-3- nitr...)
Affinity DataIC50: 9.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
University of Michigan

US Patent
LigandPNGBDBM361592(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4- ((6-(...)
Affinity DataIC50: 9.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
University of Michigan

US Patent
LigandPNGBDBM361573(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((6-(4...)
Affinity DataIC50: 10.6nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
University of Michigan

US Patent
LigandPNGBDBM361582(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((6-(4...)
Affinity DataIC50: 11.9nMAssay Description:Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respectively, were used as the fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
Go to US Patent

TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
University of Michigan

US Patent
LigandPNGBDBM361593(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4- ((6-(...)
Affinity DataIC50: 12nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
University of Michigan

US Patent
LigandPNGBDBM361588(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4- ((6-(...)
Affinity DataIC50: 13.1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
University of Michigan

US Patent
LigandPNGBDBM361574(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((6-(4...)
Affinity DataIC50: 13.7nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
University of Michigan

US Patent
LigandPNGBDBM361581(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((6-(4...)
Affinity DataIC50: 14nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
University of Michigan

US Patent
LigandPNGBDBM361576((R)-N-((4-(((1,4-dioxan-2-yl)methyl)amino)-3- nitr...)
Affinity DataIC50: 14nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
Go to US Patent

TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
University of Michigan

US Patent
LigandPNGBDBM361584((R)-N-((4-(((1,4-dioxan-2-yl)methyl)amino)-3- nitr...)
Affinity DataIC50: 14.8nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
University of Michigan

US Patent
LigandPNGBDBM361578(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(1-((6-(4...)
Affinity DataIC50: 15.7nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
University of Michigan

US Patent
LigandPNGBDBM361585(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4- ((6-(...)
Affinity DataIC50: 19.2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
University of Michigan

US Patent
LigandPNGBDBM361580(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(1-((6-(4...)
Affinity DataIC50: 20.6nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
University of Michigan

US Patent
LigandPNGBDBM361586(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4- ((6-(...)
Affinity DataIC50: 20.7nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
University of Michigan

US Patent
LigandPNGBDBM361587(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4- ((6-(...)
Affinity DataIC50: 67.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
University of Michigan

US Patent
LigandPNGBDBM361582(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((6-(4...)
Affinity DataIC50: 77.8nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
University of Michigan

US Patent
LigandPNGBDBM361583(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(1-((6-(4...)
Affinity DataIC50: 139nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Michigan

US Patent
LigandPNGBDBM361579((R)-N-((4-(((1,4-dioxan-2-yl)methyl)amino)-3- nitr...)
Affinity DataIC50: 5.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Michigan

US Patent
LigandPNGBDBM361577((S)-N-((4-(((1,4-dioxan-2-yl)methyl)amino)-3- nitr...)
Affinity DataIC50: 5.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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