Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 2183
TargetFibroblast growth factor receptor 2(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357253(US10214515, Example 16 | (5-Amino-1-(2-cyclopropyl...)
Affinity DataIC50: 0.700nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 2(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357251(US10214515, Example 13 | (5-Amino-1-(2-cyclopropyl...)
Affinity DataIC50: 2.60nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 2(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357252(US10214515, Example 15 | (5-Amino-1-(2-cyclopropyl...)
Affinity DataIC50: 2.70nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357253(US10214515, Example 16 | (5-Amino-1-(2-cyclopropyl...)
Affinity DataIC50: 4.90nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 2(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357250(US10214515, Example 12 | (5-Amino-1-(2-cyclopropyl...)
Affinity DataIC50: 5nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 2(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357254(US10214515, Example 17 | 2-(5-Amino-1-(2-cycloprop...)
Affinity DataIC50: 5nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357251(US10214515, Example 13 | (5-Amino-1-(2-cyclopropyl...)
Affinity DataIC50: 5nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 2(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357246(US10214515, Example 1 | (5-amino-1-(2-cyclopropyl-...)
Affinity DataIC50: 6.20nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357253(US10214515, Example 16 | (5-Amino-1-(2-cyclopropyl...)
Affinity DataIC50: 6.80nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357254(US10214515, Example 17 | 2-(5-Amino-1-(2-cycloprop...)
Affinity DataIC50: 8.60nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357254(US10214515, Example 17 | 2-(5-Amino-1-(2-cycloprop...)
Affinity DataIC50: 9.10nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 2(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357249(US10214515, Example 11 | (5-amino-1-(2-cyclopropyl...)
Affinity DataIC50: 10nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357252(US10214515, Example 15 | (5-Amino-1-(2-cyclopropyl...)
Affinity DataIC50: 14nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357246(US10214515, Example 1 | (5-amino-1-(2-cyclopropyl-...)
Affinity DataIC50: 15.1nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357250(US10214515, Example 12 | (5-Amino-1-(2-cyclopropyl...)
Affinity DataIC50: 18nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357250(US10214515, Example 12 | (5-Amino-1-(2-cyclopropyl...)
Affinity DataIC50: 19nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357249(US10214515, Example 11 | (5-amino-1-(2-cyclopropyl...)
Affinity DataIC50: 21nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357246(US10214515, Example 1 | (5-amino-1-(2-cyclopropyl-...)
Affinity DataIC50: 22nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357249(US10214515, Example 11 | (5-amino-1-(2-cyclopropyl...)
Affinity DataIC50: 26nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 2(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357247(US10214515, Example 7 | Methyl 5-(5-amino-4-(1H-in...)
Affinity DataIC50: 30nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 2(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357248(US10214515, Example 9 | Ethyl 5-(5-Amino-4-(1H-ind...)
Affinity DataIC50: 44nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357252(US10214515, Example 15 | (5-Amino-1-(2-cyclopropyl...)
Affinity DataIC50: 45nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357251(US10214515, Example 13 | (5-Amino-1-(2-cyclopropyl...)
Affinity DataIC50: 46nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357247(US10214515, Example 7 | Methyl 5-(5-amino-4-(1H-in...)
Affinity DataIC50: 75.3nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357247(US10214515, Example 7 | Methyl 5-(5-amino-4-(1H-in...)
Affinity DataIC50: 100nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357254(US10214515, Example 17 | 2-(5-Amino-1-(2-cycloprop...)
Affinity DataIC50: 135nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357253(US10214515, Example 16 | (5-Amino-1-(2-cyclopropyl...)
Affinity DataIC50: 280nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357250(US10214515, Example 12 | (5-Amino-1-(2-cyclopropyl...)
Affinity DataIC50: 308nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357249(US10214515, Example 11 | (5-amino-1-(2-cyclopropyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357246(US10214515, Example 1 | (5-amino-1-(2-cyclopropyl-...)
Affinity DataIC50: 1.00E+3nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357252(US10214515, Example 15 | (5-Amino-1-(2-cyclopropyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357251(US10214515, Example 13 | (5-Amino-1-(2-cyclopropyl...)
Affinity DataIC50: 1.74E+3nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357248(US10214515, Example 9 | Ethyl 5-(5-Amino-4-(1H-ind...)
Affinity DataIC50: 1.00E+4nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357247(US10214515, Example 7 | Methyl 5-(5-amino-4-(1H-in...)
Affinity DataIC50: 1.00E+4nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357248(US10214515, Example 9 | Ethyl 5-(5-Amino-4-(1H-ind...)
Affinity DataIC50: 1.00E+4nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357248(US10214515, Example 9 | Ethyl 5-(5-Amino-4-(1H-ind...)
Affinity DataIC50: 1.00E+4nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent