Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 1598
TargetEpidermal growth factor receptor(Human)
Arromax Pharmatech

US Patent
LigandPNGBDBM332539(US10196365, Compound 4 | (E)-N-(4-(3-chloro-4-fluo...)
Affinity DataIC50: 0.699nMAssay Description:The kinase analysis in vitro was performed using the HTRF kinEASE TK kit of Invitrogen Co., the procedure steps were carried out according to instruc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
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TargetEpidermal growth factor receptor(Human)
Arromax Pharmatech

US Patent
LigandPNGBDBM332536(US10196365, Compound 1 | (E)-N-(4-(3-chloro-4-fluo...)
Affinity DataIC50: 0.765nMAssay Description:The kinase analysis in vitro was performed using the HTRF kinEASE TK kit of Invitrogen Co., the procedure steps were carried out according to instruc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
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TargetEpidermal growth factor receptor(Human)
Arromax Pharmatech

US Patent
LigandPNGBDBM332542(US10196365, Compound 10 | (E)-N-(7-(2-ethoxyethoxy...)
Affinity DataIC50: 0.771nMAssay Description:The kinase analysis in vitro was performed using the HTRF kinEASE TK kit of Invitrogen Co., the procedure steps were carried out according to instruc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
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TargetEpidermal growth factor receptor(Human)
Arromax Pharmatech

US Patent
LigandPNGBDBM332537(US10196365, Compound 2 | (R,E)-N-(4-(3-chloro-4-fl...)
Affinity DataIC50: 0.950nMAssay Description:The kinase analysis in vitro was performed using the HTRF kinEASE TK kit of Invitrogen Co., the procedure steps were carried out according to instruc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
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TargetEpidermal growth factor receptor(Human)
Arromax Pharmatech

US Patent
LigandPNGBDBM50322823((S)-N-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahy...)
Affinity DataIC50: 0.965nMAssay Description:The kinase analysis in vitro was performed using the HTRF kinEASE TK kit of Invitrogen Co., the procedure steps were carried out according to instruc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
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PDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Arromax Pharmatech

US Patent
LigandPNGBDBM332545(US10196365, Compound 33 | (E)-N-(4-(3-chloro-4-flu...)
Affinity DataIC50: 1.49nMAssay Description:The kinase analysis in vitro was performed using the HTRF kinEASE TK kit of Invitrogen Co., the procedure steps were carried out according to instruc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
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TargetEpidermal growth factor receptor(Human)
Arromax Pharmatech

US Patent
LigandPNGBDBM332541(US10196365, Compound 6 | (E)-N-(4-(3-chloro-4-fluo...)
Affinity DataIC50: 1.54nMAssay Description:The kinase analysis in vitro was performed using the HTRF kinEASE TK kit of Invitrogen Co., the procedure steps were carried out according to instruc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
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TargetEpidermal growth factor receptor(Human)
Arromax Pharmatech

US Patent
LigandPNGBDBM332538(US10196365, Compound 3 | (S,E)-N-(4-(3-chloro-4-fl...)
Affinity DataIC50: 2.73nMAssay Description:The kinase analysis in vitro was performed using the HTRF kinEASE TK kit of Invitrogen Co., the procedure steps were carried out according to instruc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
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TargetEpidermal growth factor receptor(Human)
Arromax Pharmatech

US Patent
LigandPNGBDBM332540(US10196365, Compound 5 | (E)-N-(4-(3-chloro-4-fluo...)
Affinity DataIC50: 2.85nMAssay Description:The kinase analysis in vitro was performed using the HTRF kinEASE TK kit of Invitrogen Co., the procedure steps were carried out according to instruc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
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TargetReceptor tyrosine-protein kinase erbB-2(Human)
Arromax Pharmatech

US Patent
LigandPNGBDBM332542(US10196365, Compound 10 | (E)-N-(7-(2-ethoxyethoxy...)
Affinity DataIC50: 3.63nMAssay Description:The kinase analysis in vitro was performed using the HTRF kinEASE TK kit of Invitrogen Co., the procedure steps were carried out according to instruc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
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TargetEpidermal growth factor receptor(Human)
Arromax Pharmatech

US Patent
LigandPNGBDBM332544(US10196365, Compound 12 | (E)-N-(4-(3-chloro-4-(py...)
Affinity DataIC50: 10.2nMAssay Description:The kinase analysis in vitro was performed using the HTRF kinEASE TK kit of Invitrogen Co., the procedure steps were carried out according to instruc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
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TargetReceptor tyrosine-protein kinase erbB-2(Human)
Arromax Pharmatech

US Patent
LigandPNGBDBM332545(US10196365, Compound 33 | (E)-N-(4-(3-chloro-4-flu...)
Affinity DataIC50: 10.9nMAssay Description:The kinase analysis in vitro was performed using the HTRF kinEASE TK kit of Invitrogen Co., the procedure steps were carried out according to instruc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
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TargetReceptor tyrosine-protein kinase erbB-2(Human)
Arromax Pharmatech

US Patent
LigandPNGBDBM332536(US10196365, Compound 1 | (E)-N-(4-(3-chloro-4-fluo...)
Affinity DataIC50: 39.3nMAssay Description:The kinase analysis in vitro was performed using the HTRF kinEASE TK kit of Invitrogen Co., the procedure steps were carried out according to instruc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
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TargetReceptor tyrosine-protein kinase erbB-2(Human)
Arromax Pharmatech

US Patent
LigandPNGBDBM332539(US10196365, Compound 4 | (E)-N-(4-(3-chloro-4-fluo...)
Affinity DataIC50: 42.1nMAssay Description:The kinase analysis in vitro was performed using the HTRF kinEASE TK kit of Invitrogen Co., the procedure steps were carried out according to instruc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
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TargetReceptor tyrosine-protein kinase erbB-2(Human)
Arromax Pharmatech

US Patent
LigandPNGBDBM332544(US10196365, Compound 12 | (E)-N-(4-(3-chloro-4-(py...)
Affinity DataIC50: 53.9nMAssay Description:The kinase analysis in vitro was performed using the HTRF kinEASE TK kit of Invitrogen Co., the procedure steps were carried out according to instruc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
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TargetReceptor tyrosine-protein kinase erbB-2(Human)
Arromax Pharmatech

US Patent
LigandPNGBDBM50322823((S)-N-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahy...)
Affinity DataIC50: 73.7nMAssay Description:The kinase analysis in vitro was performed using the HTRF kinEASE TK kit of Invitrogen Co., the procedure steps were carried out according to instruc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
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TargetReceptor tyrosine-protein kinase erbB-2(Human)
Arromax Pharmatech

US Patent
LigandPNGBDBM332541(US10196365, Compound 6 | (E)-N-(4-(3-chloro-4-fluo...)
Affinity DataIC50: 83.8nMAssay Description:The kinase analysis in vitro was performed using the HTRF kinEASE TK kit of Invitrogen Co., the procedure steps were carried out according to instruc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
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TargetReceptor tyrosine-protein kinase erbB-2(Human)
Arromax Pharmatech

US Patent
LigandPNGBDBM332540(US10196365, Compound 5 | (E)-N-(4-(3-chloro-4-fluo...)
Affinity DataIC50: 132nMAssay Description:The kinase analysis in vitro was performed using the HTRF kinEASE TK kit of Invitrogen Co., the procedure steps were carried out according to instruc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
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TargetReceptor tyrosine-protein kinase erbB-2(Human)
Arromax Pharmatech

US Patent
LigandPNGBDBM332537(US10196365, Compound 2 | (R,E)-N-(4-(3-chloro-4-fl...)
Affinity DataIC50: 148nMAssay Description:The kinase analysis in vitro was performed using the HTRF kinEASE TK kit of Invitrogen Co., the procedure steps were carried out according to instruc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor(Human)
Arromax Pharmatech

US Patent
LigandPNGBDBM332543(US10196365, Compound 11 | (E) N (4 (4 (3 fluoroben...)
Affinity DataIC50: 154nMAssay Description:The kinase analysis in vitro was performed using the HTRF kinEASE TK kit of Invitrogen Co., the procedure steps were carried out according to instruc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
Go to US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Arromax Pharmatech

US Patent
LigandPNGBDBM332543(US10196365, Compound 11 | (E) N (4 (4 (3 fluoroben...)
Affinity DataIC50: 262nMAssay Description:The kinase analysis in vitro was performed using the HTRF kinEASE TK kit of Invitrogen Co., the procedure steps were carried out according to instruc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
Go to US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Arromax Pharmatech

US Patent
LigandPNGBDBM332538(US10196365, Compound 3 | (S,E)-N-(4-(3-chloro-4-fl...)
Affinity DataIC50: 482nMAssay Description:The kinase analysis in vitro was performed using the HTRF kinEASE TK kit of Invitrogen Co., the procedure steps were carried out according to instruc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
Go to US Patent