Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 1450
TargetMineralocorticoid receptor(Human)
Allergan

US Patent
LigandPNGBDBM19214([3H]Aldosterone | (1S,2R,10S,11S,14S,15R,17S)-17-h...)
Affinity DataEC50:  0.470nMAssay Description:Mineralocorticoid receptor (MR) activation potency was assessed using a HEK 293T cell line containing the UAS-bla reporter (UAS-bla HEK 293T CELLSENS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
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TargetMineralocorticoid receptor(Human)
Allergan

US Patent
LigandPNGBDBM323670(US10188667, Example 00011 | US10188667, Example 00...)
Affinity DataEC50: >100nMAssay Description:Mineralocorticoid receptor (MR) activation potency was assessed using a HEK 293T cell line containing the UAS-bla reporter (UAS-bla HEK 293T CELLSENS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
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TargetMineralocorticoid receptor(Human)
Allergan

US Patent
LigandPNGBDBM323676(US10188667, Example 00030 | US10188667, Example 00...)
Affinity DataEC50:  15.6nMAssay Description:Mineralocorticoid receptor (MR) activation potency was assessed using a HEK 293T cell line containing the UAS-bla reporter (UAS-bla HEK 293T CELLSENS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
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TargetMineralocorticoid receptor(Human)
Allergan

US Patent
LigandPNGBDBM323674(US10188667, Example 00029 | US10188667, Example 00...)
Affinity DataEC50:  9.29nMAssay Description:Mineralocorticoid receptor (MR) activation potency was assessed using a HEK 293T cell line containing the UAS-bla reporter (UAS-bla HEK 293T CELLSENS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
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TargetMineralocorticoid receptor(Human)
Allergan

US Patent
LigandPNGBDBM323671(US10188667, Example 00012 | US10188667, Example 00...)
Affinity DataEC50:  7.46nMAssay Description:Mineralocorticoid receptor (MR) activation potency was assessed using a HEK 293T cell line containing the UAS-bla reporter (UAS-bla HEK 293T CELLSENS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
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TargetMineralocorticoid receptor(Human)
Allergan

US Patent
LigandPNGBDBM323673(US10188667, Example 00027 | US10188667, Example 00...)
Affinity DataEC50:  5.68nMAssay Description:Mineralocorticoid receptor (MR) activation potency was assessed using a HEK 293T cell line containing the UAS-bla reporter (UAS-bla HEK 293T CELLSENS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
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TargetMineralocorticoid receptor(Human)
Allergan

US Patent
LigandPNGBDBM323674(US10188667, Example 00029 | US10188667, Example 00...)
Affinity DataEC50:  5.27nMAssay Description:Mineralocorticoid receptor (MR) activation potency was assessed using a HEK 293T cell line containing the UAS-bla reporter (UAS-bla HEK 293T CELLSENS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
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TargetMineralocorticoid receptor(Human)
Allergan

US Patent
LigandPNGBDBM323675(US10188667, Example 00025 | US10188667, Example 00...)
Affinity DataEC50:  3.17nMAssay Description:Mineralocorticoid receptor (MR) activation potency was assessed using a HEK 293T cell line containing the UAS-bla reporter (UAS-bla HEK 293T CELLSENS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
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TargetMineralocorticoid receptor(Human)
Allergan

US Patent
LigandPNGBDBM323672(US10188667, Example 00024 | US10188667, Example 00...)
Affinity DataEC50:  2.94nMAssay Description:Mineralocorticoid receptor (MR) activation potency was assessed using a HEK 293T cell line containing the UAS-bla reporter (UAS-bla HEK 293T CELLSENS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
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TargetMineralocorticoid receptor(Human)
Allergan

US Patent
LigandPNGBDBM13775([3H]cortisol | (1S,2R,10S,11S,14R,15S,17S)-14,17-d...)
Affinity DataEC50:  2.90nMAssay Description:Mineralocorticoid receptor (MR) activation potency was assessed using a HEK 293T cell line containing the UAS-bla reporter (UAS-bla HEK 293T CELLSENS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
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TargetMineralocorticoid receptor(Human)
Allergan

US Patent
LigandPNGBDBM323679(US10188667, Example 00020 | US10188667, Example 00...)
Affinity DataEC50:  2.85nMAssay Description:Mineralocorticoid receptor (MR) activation potency was assessed using a HEK 293T cell line containing the UAS-bla reporter (UAS-bla HEK 293T CELLSENS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
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TargetRho GTPase-activating protein 35(Human)
Allergan

US Patent
LigandPNGBDBM323654(US10188667, Dexamethasone)
Affinity DataEC50:  1.05nMAssay Description:Glucocorticoid receptor (GR) activation potency was assessed using a HeLa cell line containing the MMTV-bla reporter (MMTV-bla HeLa CELLSENSOR , Invi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
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TargetRho GTPase-activating protein 35(Human)
Allergan

US Patent
LigandPNGBDBM323679(US10188667, Example 00020 | US10188667, Example 00...)
Affinity DataEC50: >100nMAssay Description:Glucocorticoid receptor (GR) activation potency was assessed using a HeLa cell line containing the MMTV-bla reporter (MMTV-bla HeLa CELLSENSOR , Invi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
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TargetRho GTPase-activating protein 35(Human)
Allergan

US Patent
LigandPNGBDBM323674(US10188667, Example 00029 | US10188667, Example 00...)
Affinity DataEC50: >100nMAssay Description:Glucocorticoid receptor (GR) activation potency was assessed using a HeLa cell line containing the MMTV-bla reporter (MMTV-bla HeLa CELLSENSOR , Invi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
Go to US Patent

TargetRho GTPase-activating protein 35(Human)
Allergan

US Patent
LigandPNGBDBM13775([3H]cortisol | (1S,2R,10S,11S,14R,15S,17S)-14,17-d...)
Affinity DataEC50:  41.6nMAssay Description:Glucocorticoid receptor (GR) activation potency was assessed using a HeLa cell line containing the MMTV-bla reporter (MMTV-bla HeLa CELLSENSOR , Invi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
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TargetRho GTPase-activating protein 35(Human)
Allergan

US Patent
LigandPNGBDBM323676(US10188667, Example 00030 | US10188667, Example 00...)
Affinity DataEC50:  7.07nMAssay Description:Glucocorticoid receptor (GR) activation potency was assessed using a HeLa cell line containing the MMTV-bla reporter (MMTV-bla HeLa CELLSENSOR , Invi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
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TargetRho GTPase-activating protein 35(Human)
Allergan

US Patent
LigandPNGBDBM323675(US10188667, Example 00025 | US10188667, Example 00...)
Affinity DataEC50:  6.31nMAssay Description:Glucocorticoid receptor (GR) activation potency was assessed using a HeLa cell line containing the MMTV-bla reporter (MMTV-bla HeLa CELLSENSOR , Invi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
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TargetRho GTPase-activating protein 35(Human)
Allergan

US Patent
LigandPNGBDBM323674(US10188667, Example 00029 | US10188667, Example 00...)
Affinity DataEC50:  6.04nMAssay Description:Glucocorticoid receptor (GR) activation potency was assessed using a HeLa cell line containing the MMTV-bla reporter (MMTV-bla HeLa CELLSENSOR , Invi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
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TargetRho GTPase-activating protein 35(Human)
Allergan

US Patent
LigandPNGBDBM323673(US10188667, Example 00027 | US10188667, Example 00...)
Affinity DataEC50:  3.25nMAssay Description:Glucocorticoid receptor (GR) activation potency was assessed using a HeLa cell line containing the MMTV-bla reporter (MMTV-bla HeLa CELLSENSOR , Invi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
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TargetRho GTPase-activating protein 35(Human)
Allergan

US Patent
LigandPNGBDBM323672(US10188667, Example 00024 | US10188667, Example 00...)
Affinity DataEC50:  1.97nMAssay Description:Glucocorticoid receptor (GR) activation potency was assessed using a HeLa cell line containing the MMTV-bla reporter (MMTV-bla HeLa CELLSENSOR , Invi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
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TargetRho GTPase-activating protein 35(Human)
Allergan

US Patent
LigandPNGBDBM323671(US10188667, Example 00012 | US10188667, Example 00...)
Affinity DataEC50:  1.41nMAssay Description:Glucocorticoid receptor (GR) activation potency was assessed using a HeLa cell line containing the MMTV-bla reporter (MMTV-bla HeLa CELLSENSOR , Invi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
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TargetRho GTPase-activating protein 35(Human)
Allergan

US Patent
LigandPNGBDBM323670(US10188667, Example 00011 | US10188667, Example 00...)
Affinity DataEC50:  1.35nMAssay Description:Glucocorticoid receptor (GR) activation potency was assessed using a HeLa cell line containing the MMTV-bla reporter (MMTV-bla HeLa CELLSENSOR , Invi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
Go to US Patent