Compile Data Set for Download or QSAR
Report error Found 195 Enz. Inhib. hit(s) with all data for entry = 1446
TargetRetinoic acid receptor gamma(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323587BDBM323587(4-[(E)-2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2...)
Affinity DataEC50:  0.0650nMAssay Description:Retinoid nuclear receptor activity is associated with transduction of the non-visual physiologic, pharmacologic, and toxicologic retinoid signals tha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoic acid receptor beta(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323587BDBM323587(4-[(E)-2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2...)
Affinity DataEC50:  0.300nMAssay Description:Retinoid nuclear receptor activity is associated with transduction of the non-visual physiologic, pharmacologic, and toxicologic retinoid signals tha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoic acid receptor alpha(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323587BDBM323587(4-[(E)-2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2...)
Affinity DataEC50:  5.5nMAssay Description:Retinoid nuclear receptor activity is associated with transduction of the non-visual physiologic, pharmacologic, and toxicologic retinoid signals tha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323450BDBM323450((S)-3-Amino-1-(3-(Cyclohexylmethoxy)Phenyl)Propan-...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323449BDBM323449(2-(3-(2-Propylpentyloxy)Phenoxy)Ethanamine | US101...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323452BDBM323452(2-(3-(2-Ethylbutoxy)Phenoxy)Ethanamine | US1018861...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323451BDBM323451(3-((3-(3-Aminopropyl)Phenoxy)Methyl)Pentan-3-Ol | ...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323454BDBM323454(2-(3-(Isopentyloxy)Phenoxy)Ethanamine | US10188615...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323453BDBM323453(3-Amino-1-(3-(Benzyloxy)Phenyl)Propan-1-Ol | US101...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323456BDBM323456((1R,2R)-2-(Aminomethyl)-1-(3-(Cyclohexylmethoxy)Ph...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323455BDBM323455(2-(3-Phenethoxyphenoxy)Ethanamine | US10188615, Ex...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323441BDBM323441(1-Amino-3-(3-(Cyclohexylmethoxy)Phenyl)Propan-2-Ol...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323440BDBM323440(3-Amino-1-(3-(Cyclohexylmethoxy)Phenyl)Propan-1-On...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323444BDBM323444(2-(3-(Cycloheptylmethoxy)Phenoxy)Ethanamine | US10...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323442BDBM323442(2-(3-(Cyclohexylmethoxy)Phenoxy)Ethanamine | US101...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323446BDBM323446(1-((3-(3-Amino-1-Hydroxypropyl)Phenoxy)Methyl)Cycl...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323445BDBM323445(1-((3-(3-Aminopropyl)Phenoxy)Methyl)Cyclohexanol |...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323448BDBM323448(4-((3-(3-Amino-1-Hydroxypropyl)Phenoxy)Methyl)Hept...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323447BDBM323447(3-Amino-1-(3-(Cycloheptylmethoxy)Phenyl)Propan-1-O...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323466BDBM323466(3-Amino-1-(3-((Tetrahydro-2H-Pyran-2-Yl)Methoxy)Ph...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323465BDBM323465(3-(3-(Cyclohexylmethoxy)Phenyl)Butan-1-Amine | US1...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323468BDBM323468(3-Amino-1-(3-(2-Methoxybenzyloxy)Phenyl)Propan-1-O...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323467BDBM323467(2-(3-(Pentyloxy)Phenoxy)Ethanamine | US10188615, E...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323470BDBM323470(3-(3-(Cyclopentylmethoxy)Phenyl)Propan-1-Amine | U...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323469BDBM323469(2-(3-(Cyclooctylmethoxy)Phenoxy)Ethanamine | US101...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323472BDBM323472(3-Amino-1-(3-(2,6-Dichlorobenzyloxy)Phenyl)Propan-...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323471BDBM323471(2-(3-(Cyclopentylmethoxy)Phenoxy)Ethanamine | US10...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323458BDBM323458((S)-1-Amino-3-(3-(2-Ethylbutoxy)Phenyl)Propan-2-Ol...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323457BDBM323457(3-Amino-1-(3-Phenethoxyphenyl)Propan-1-Ol | US1018...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323460BDBM323460((R)-1-Amino-3-(3-(2-Propylpentyloxy)Phenyl)Propan-...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323459BDBM323459((S)-1-Amino-3-(3-(2-Propylpentyloxy)Phenyl)Propan-...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323462BDBM323462(3-Amino-1-(3-(Cyclopropylmethoxy)Phenyl)Propan-1-O...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323461BDBM323461((R)-1-Amino-3-(3-(2-Ethylbutoxy)Phenyl)Propan-2-Ol...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323464BDBM323464((1R,2S)-3-Amino-1-(3-(Cyclohexylmethoxy)Phenyl)-2-...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323463BDBM323463((1S,2S)-3-Amino-1-(3-(Cyclohexylmethoxy)Phenyl)-2-...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323483BDBM323483((1,2-Trans)-2-((3-(3-Aminopropyl)Phenoxy)Methyl)Cy...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323482BDBM323482((1,2-Cis)-2-((3-(3-Aminopropyl)Phenoxy)Methyl)Cycl...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323485BDBM323485(1-(3-(3-Amino-1-Hydroxypropyl)Phenoxy)-3-Methylbut...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323484BDBM323484(2-(3-(Cyclohexylmethoxy)-5-Methylphenoxy)Ethanamin...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323487BDBM323487(1-(3-(3-Amino-1-Hydroxypropyl)Phenoxy)Pentan-2-Ol ...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323486BDBM323486(3-Amino-1-(3-(2-Hydroxy-2-Phenylethoxy)Phenyl)Prop...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323488BDBM323488(5-(3-(3-Amino-1-Hydroxypropyl)Phenoxy)Pentan-1-Ol ...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323475BDBM323475(3-Amino-1-(3-(Isopentyloxy)Phenyl)Propan-1-Ol | US...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323474BDBM323474(3-Amino-1-(3-(Cyclooctylmethoxy)Phenyl)Propan-1-Ol...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323477BDBM323477(3-Amino-1-(3-(4-(Benzyloxy)Butoxy)Phenyl)Propan-1-...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323476BDBM323476(3-Amino-1-(3-(3-Methoxypropoxy)Phenyl)Propan-1-Ol ...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323479BDBM323479(2-(3-(Cyclohexylmethoxy)Phenylthio)Ethanamine | US...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323478BDBM323478(3-Amino-1-(3-(5-(Benzyloxy)Pentyloxy)Phenyl)Propan...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323481BDBM323481(3-Amino-1-(3-(3-(Benzyloxy)Propoxy)Phenyl)Propan-1...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandChemical structure of BindingDB Monomer ID 323480BDBM323480(3-(3-(Cyclohexylmethoxy)Phenyl)-3-Hydroxypropanimi...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

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