Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 1386
LigandPNGBDBM319787(US10174013, Example 2A | 5,6-dibromo-4-nitro-2-(pi...)
Affinity DataKd:  15nMAssay Description:Selected compounds were also tested for their binding properties against FLT3 kinase mutants using suitable in vitro assays (performed according to s...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319787(US10174013, Example 2A | 5,6-dibromo-4-nitro-2-(pi...)
Affinity DataKd:  28nMAssay Description:Selected compounds were also tested for their binding properties against FLT3 kinase mutants using suitable in vitro assays (performed according to s...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Selvita

US Patent
LigandPNGBDBM319787(US10174013, Example 2A | 5,6-dibromo-4-nitro-2-(pi...)
Affinity DataKd:  18nMAssay Description:Selected compounds were also tested for their binding properties against FLT3 kinase mutants using suitable in vitro assays (performed according to s...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Selvita

US Patent
LigandPNGBDBM319787(US10174013, Example 2A | 5,6-dibromo-4-nitro-2-(pi...)
Affinity DataKd:  130nMAssay Description:Selected compounds were also tested for their binding properties against FLT3 kinase mutants using suitable in vitro assays (performed according to s...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319752(US10174013, Example 1A | US10174013, Example 1Y | ...)
Affinity DataKd:  46nMAssay Description:Selected compounds were also tested for their binding properties against FLT3 kinase mutants using suitable in vitro assays (performed according to s...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319752(US10174013, Example 1A | US10174013, Example 1Y | ...)
Affinity DataKd:  120nMAssay Description:Selected compounds were also tested for their binding properties against FLT3 kinase mutants using suitable in vitro assays (performed according to s...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Selvita

US Patent
LigandPNGBDBM319752(US10174013, Example 1A | US10174013, Example 1Y | ...)
Affinity DataKd:  74nMAssay Description:Selected compounds were also tested for their binding properties against FLT3 kinase mutants using suitable in vitro assays (performed according to s...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Selvita

US Patent
LigandPNGBDBM319752(US10174013, Example 1A | US10174013, Example 1Y | ...)
Affinity DataKd:  400nMAssay Description:Selected compounds were also tested for their binding properties against FLT3 kinase mutants using suitable in vitro assays (performed according to s...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319770(US10174013, Example 1AE)
Affinity DataIC50: 400nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319772(US10174013, Example 1AI)
Affinity DataIC50: 440nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319757(US10174013, Example 1M)
Affinity DataIC50: 520nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319786(US10174013, Example 1BM)
Affinity DataIC50: 740nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319753(US10174013, Example 8A)
Affinity DataIC50: 770nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319755(US10174013, Example 22L | US10174013, Example 22J ...)
Affinity DataIC50: 850nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319779(US10174013, Example 1AX)
Affinity DataIC50: 1.23E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319758(US10174013, Example 1N)
Affinity DataIC50: 1.28E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319769(US10174013, Example 1AD)
Affinity DataIC50: 1.42E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319774(US10174013, Example 1AM)
Affinity DataIC50: 1.46E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319752(US10174013, Example 1A | US10174013, Example 1Y | ...)
Affinity DataIC50: 1.60E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319759(US10174013, Example 2A | US10174013, Example 2D | ...)
Affinity DataIC50: 1.60E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319755(US10174013, Example 22L | US10174013, Example 22J ...)
Affinity DataIC50: 1.78E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319775(US10174013, Example 1AP)
Affinity DataIC50: 1.82E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319776(US10174013, Example 1AQ)
Affinity DataIC50: 1.86E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319768(US10174013, Example 1AC)
Affinity DataIC50: 1.86E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319760(US10174013, Example 1P)
Affinity DataIC50: 1.88E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319781(US10174013, Example 1AZ)
Affinity DataIC50: 1.88E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319755(US10174013, Example 22L | US10174013, Example 22J ...)
Affinity DataIC50: 2.02E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319765(US10174013, Example 1AA)
Affinity DataIC50: 2.27E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319773(US10174013, Example 1AL)
Affinity DataIC50: 2.42E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319759(US10174013, Example 2A | US10174013, Example 2D | ...)
Affinity DataIC50: 2.50E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319759(US10174013, Example 2A | US10174013, Example 2D | ...)
Affinity DataIC50: 3.06E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319780(US10174013, Example 1AY)
Affinity DataIC50: 3.88E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319777(US10174013, Example 1AR)
Affinity DataIC50: 4.17E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319784(US10174013, Example 1BD)
Affinity DataIC50: 4.34E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319771(US10174013, Example 1AH)
Affinity DataIC50: 4.99E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319783(US10174013, Example 1BI)
Affinity DataIC50: 5.17E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319778(US10174013, Example 1AS)
Affinity DataIC50: 5.77E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319767(US10174013, Example 1AB)
Affinity DataIC50: 8.93E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319755(US10174013, Example 22L | US10174013, Example 22J ...)
Affinity DataIC50: 1.01E+4nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319755(US10174013, Example 22L | US10174013, Example 22J ...)
Affinity DataIC50: 1.19E+4nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319752(US10174013, Example 1A | US10174013, Example 1Y | ...)
Affinity DataIC50: 1.69E+4nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM319752(US10174013, Example 1A | US10174013, Example 1Y | ...)
Affinity DataIC50: 2.04E+4nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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