Compile Data Set for Download or QSAR
Report error Found 1229 Enz. Inhib. hit(s) with all data for entry = 1301
LigandPNGBDBM296817(US10112942, Example 552 | US10137124, Example 552 ...)
Affinity DataIC50: 1nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM296818(US10112942, Example 553 | US10137124, Example 553 ...)
Affinity DataIC50: 2nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM296816(US10112942, Example 551 | US10137124, Example 551 ...)
Affinity DataIC50: 3nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM296809(US10112942, Example 544 | US10137124, Example 544 ...)
Affinity DataIC50: 4nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296821(US10112942, Example 556 | US10137124, Example 556 ...)
Affinity DataIC50: 4nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296696(US10112942, Example 431 | US10137124, Example 431 ...)
Affinity DataIC50: 4.5nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM296733(US10112942, Example 468 | US10137124, Example 468 ...)
Affinity DataIC50: 4.80nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296812(US10112942, Example 547 | 6-ethoxy-4-(5-(6-(3- flu...)
Affinity DataIC50: 5nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296735(US10112942, Example 470 | US10137124, Example 470 ...)
Affinity DataIC50: 5.5nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM296726(US10112942, Example 461 | US10137124, Example 461 ...)
Affinity DataIC50: 5.60nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM296708(US10112942, Example 443 | US10137124, Example 443 ...)
Affinity DataIC50: 6.5nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296808(US10112942, Example 546 | US10112942, Example 543 ...)
Affinity DataIC50: 7nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296817(US10112942, Example 552 | US10137124, Example 552 ...)
Affinity DataIC50: 7nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296745(US10112942, Example 480 | US10137124, Example 480 ...)
Affinity DataIC50: 7.40nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296709(US10112942, Example 444 | US10137124, Example 444 ...)
Affinity DataIC50: 7.80nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM315457(US10172851, Example 110)
Affinity DataIC50: 8.10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296710(US10112942, Example 445 | US10137124, Example 445 ...)
Affinity DataIC50: 8.20nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296716(US10112942, Example 451 | US10137124, Example 451 ...)
Affinity DataIC50: 8.30nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296727(US10112942, Example 462 | US10137124, Example 462 ...)
Affinity DataIC50: 9nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296747(US10112942, Example 482 | US10137124, Example 482 ...)
Affinity DataIC50: 9.10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296718(US10112942, Example 453 | US10137124, Example 453 ...)
Affinity DataIC50: 9.20nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296699(US10112942, Example 434 | US10137124, Example 434 ...)
Affinity DataIC50: 9.30nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM296547(US10112942, Example 281 | 6-(2-hydroxy-2- methylpr...)
Affinity DataIC50: 9.40nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296597(US10112942, Example 331 | 4-(6-(6-(4- (difluoromet...)
Affinity DataIC50: 9.40nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296205(US10112942, Example 12 | US10137124, Example 12 | ...)
Affinity DataIC50: 9.5nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296700(US10112942, Example 435 | US10137124, Example 435 ...)
Affinity DataIC50: 9.5nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296711(US10112942, Example 446 | US10137124, Example 446 ...)
Affinity DataIC50: 9.5nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296581(US10112942, Example 315 | US10137124, Example 315 ...)
Affinity DataIC50: 9.60nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296713(US10112942, Example 448 | US10137124, Example 448 ...)
Affinity DataIC50: 9.60nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296543(US10112942, Example 277 | US10137124, Example 277 ...)
Affinity DataIC50: 9.70nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296731(US10112942, Example 466 | US10137124, Example 466 ...)
Affinity DataIC50: 9.70nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296226(US10112942, Example 33 | US10137124, Example 33 | ...)
Affinity DataIC50: 9.90nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296589(US10112942, Example 323 | US10137124, Example 323 ...)
Affinity DataIC50: 9.90nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296772(US10112942, Example 507 | US10137124, Example 507 ...)
Affinity DataIC50: 10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296814(US10112942, Example 549 | US10137124, Example 549 ...)
Affinity DataIC50: 10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296824(US10112942, Example 559 | 6-ethoxy-4-(5-(6-((6- me...)
Affinity DataIC50: 10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM315476(US10172851, Example 128)
Affinity DataIC50: 10.2nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296546(US10112942, Example 280 | US10137124, Example 280 ...)
Affinity DataIC50: 10.2nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296733(US10112942, Example 468 | US10137124, Example 468 ...)
Affinity DataIC50: 10.2nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296703(US10112942, Example 438 | US10137124, Example 438 ...)
Affinity DataIC50: 10.4nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296735(US10112942, Example 470 | US10137124, Example 470 ...)
Affinity DataIC50: 10.4nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296515(US10112942, Example 249 | US10137124, Example 249 ...)
Affinity DataIC50: 10.6nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM315816(US10172851, Example 459)
Affinity DataIC50: 10.6nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296816(US10112942, Example 551 | US10137124, Example 551 ...)
Affinity DataIC50: 11nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296818(US10112942, Example 553 | US10137124, Example 553 ...)
Affinity DataIC50: 11nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296212(US10112942, Example 19 | US10137124, Example 19 | ...)
Affinity DataIC50: 11.4nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296590(US10112942, Example 324 | 4-(6-(6-(3-chloro- 4- me...)
Affinity DataIC50: 11.4nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296715(US10112942, Example 450 | US10137124, Example 450 ...)
Affinity DataIC50: 11.4nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296211(US10112942, Example 18 | US10137124, Example 18 | ...)
Affinity DataIC50: 11.7nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM296708(US10112942, Example 443 | US10137124, Example 443 ...)
Affinity DataIC50: 11.9nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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