Compile Data Set for Download or QSAR
Report error Found 66 Enz. Inhib. hit(s) with all data for entry = 1030
TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303815BDBM303815(4-({2-[11-Chloro-7-(fluoromethyl)-2,5-dioxo-5,6,7,...)
Affinity DataIC50: 1.20nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303810BDBM303810(4-{[2-(11′-Chloro-2′,5′-dioxo-2&...)
Affinity DataIC50: 1.80nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303794BDBM303794(4-{[2-(11′-Chloro-2′,5′-dioxo-2&...)
Affinity DataIC50: 1.90nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303807BDBM303807(4-{[2-(11′-Chloro-2′,5′-dioxo-2&...)
Affinity DataIC50: 2.5nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303813BDBM303813(2-[11-Chloro-7-(fluoromethyl)-2,5-dioxo-5,6,7,8-te...)
Affinity DataIC50: 2.80nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303804BDBM303804(5-{[2-(11′-Chloro-2′,5′-dioxo-2&...)
Affinity DataIC50: 4nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303811BDBM303811(2-(11′-Chloro-2′,5′-dioxo-2̸...)
Affinity DataIC50: 4.5nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303812BDBM303812(2-(11′-Chloro-2′,5′-dioxo-2̸...)
Affinity DataIC50: 4.5nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303814BDBM303814(4-({2-[11-Chloro-7-(fluoromethyl)-2,5-dioxo-5,6,7,...)
Affinity DataIC50: 5.30nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303792BDBM303792(4-{[2-(11′-Chloro-2′,5′-dioxo-2&...)
Affinity DataIC50: 7.70nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303797BDBM303797(2-(11′-Chloro-2′,5′-dioxo-2̸...)
Affinity DataIC50: 8.20nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303801BDBM303801(2-(11′-Chloro-2′,5′-dioxo-2̸...)
Affinity DataIC50: 8.40nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303798BDBM303798(2-(11′-Chloro-2′,5′-dioxo-2̸...)
Affinity DataIC50: 11nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303793BDBM303793(2-(11′-Chloro-2′,5′-dioxo-2̸...)
Affinity DataIC50: 16nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303809BDBM303809(2-(11′-Chloro-2′,5′-dioxo-2̸...)
Affinity DataIC50: 18nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303796BDBM303796(2-(11′-Chloro-2′,5′-dioxo-2̸...)
Affinity DataIC50: 18nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303800BDBM303800(2-(11′-Chloro-2′,5′-dioxo-2̸...)
Affinity DataIC50: 21nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303795BDBM303795(4-{[2-(11′-Chloro-2′,5′-dioxo-2&...)
Affinity DataIC50: 27nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303788BDBM303788(4-{[2-(11-Chloro-2,5-dioxo-5,6,7,8-tetrahydropyrid...)
Affinity DataIC50: 28nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303808BDBM303808(4-{[2-(11′-Chloro-2′,5′-dioxo-2&...)
Affinity DataIC50: 34nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303803BDBM303803(5-{[2-(11′-Chloro-2′,5′-dioxo-2&...)
Affinity DataIC50: 34nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303806BDBM303806(4-{[2-(11′-Chloro-2′,5′-dioxo-2&...)
Affinity DataIC50: 35nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303790BDBM303790(4-{[2-(11-Chloro-2,5-dioxo-5,6,7,8-tetrahydropyrid...)
Affinity DataIC50: 36nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303811BDBM303811(2-(11′-Chloro-2′,5′-dioxo-2̸...)
Affinity DataIC50: 42nMAssay Description:o determine the plasma kallikrein inhibition of the substances according to the invention, a biochemical test system is used which utilizes the react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303813BDBM303813(2-[11-Chloro-7-(fluoromethyl)-2,5-dioxo-5,6,7,8-te...)
Affinity DataIC50: 42nMAssay Description:o determine the plasma kallikrein inhibition of the substances according to the invention, a biochemical test system is used which utilizes the react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303789BDBM303789(2-(11-Chloro-2,5-dioxo-5,6,7,8-tetrahydropyrido[3,...)
Affinity DataIC50: 44nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303799BDBM303799(2-(11′-Chloro-2′,5′-dioxo-2̸...)
Affinity DataIC50: 44nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303812BDBM303812(2-(11′-Chloro-2′,5′-dioxo-2̸...)
Affinity DataIC50: 45nMAssay Description:o determine the plasma kallikrein inhibition of the substances according to the invention, a biochemical test system is used which utilizes the react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303802BDBM303802(5-{[2-(11′-Chloro-2′,5′-dioxo-2&...)
Affinity DataIC50: 47nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303810BDBM303810(4-{[2-(11′-Chloro-2′,5′-dioxo-2&...)
Affinity DataIC50: 55nMAssay Description:o determine the plasma kallikrein inhibition of the substances according to the invention, a biochemical test system is used which utilizes the react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303815BDBM303815(4-({2-[11-Chloro-7-(fluoromethyl)-2,5-dioxo-5,6,7,...)
Affinity DataIC50: 97nMAssay Description:o determine the plasma kallikrein inhibition of the substances according to the invention, a biochemical test system is used which utilizes the react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303805BDBM303805(5-{[2-(11′-Chloro-2′,5′-dioxo-2&...)
Affinity DataIC50: 100nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303814BDBM303814(4-({2-[11-Chloro-7-(fluoromethyl)-2,5-dioxo-5,6,7,...)
Affinity DataIC50: 100nMAssay Description:o determine the plasma kallikrein inhibition of the substances according to the invention, a biochemical test system is used which utilizes the react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303791BDBM303791(2-(11-Chloro-2,5-dioxo-5,6,7,8-tetrahydropyrido[3,...)
Affinity DataIC50: 140nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303785BDBM303785(4-{[2-(10′-Chloro-2′,5′-dioxo-5&...)
Affinity DataIC50: 180nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303798BDBM303798(2-(11′-Chloro-2′,5′-dioxo-2̸...)
Affinity DataIC50: 210nMAssay Description:o determine the plasma kallikrein inhibition of the substances according to the invention, a biochemical test system is used which utilizes the react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303796BDBM303796(2-(11′-Chloro-2′,5′-dioxo-2̸...)
Affinity DataIC50: 230nMAssay Description:o determine the plasma kallikrein inhibition of the substances according to the invention, a biochemical test system is used which utilizes the react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303801BDBM303801(2-(11′-Chloro-2′,5′-dioxo-2̸...)
Affinity DataIC50: 230nMAssay Description:o determine the plasma kallikrein inhibition of the substances according to the invention, a biochemical test system is used which utilizes the react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303797BDBM303797(2-(11′-Chloro-2′,5′-dioxo-2̸...)
Affinity DataIC50: 240nMAssay Description:o determine the plasma kallikrein inhibition of the substances according to the invention, a biochemical test system is used which utilizes the react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303809BDBM303809(2-(11′-Chloro-2′,5′-dioxo-2̸...)
Affinity DataIC50: 250nMAssay Description:o determine the plasma kallikrein inhibition of the substances according to the invention, a biochemical test system is used which utilizes the react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303784BDBM303784(2-(10-Chloro-2,5-dioxo-2,5,6,7-tetrahydro-3H-pyrid...)
Affinity DataIC50: 280nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303800BDBM303800(2-(11′-Chloro-2′,5′-dioxo-2̸...)
Affinity DataIC50: 330nMAssay Description:o determine the plasma kallikrein inhibition of the substances according to the invention, a biochemical test system is used which utilizes the react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303804BDBM303804(5-{[2-(11′-Chloro-2′,5′-dioxo-2&...)
Affinity DataIC50: 340nMAssay Description:o determine the plasma kallikrein inhibition of the substances according to the invention, a biochemical test system is used which utilizes the react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303787BDBM303787(2-(11-Chloro-2,5-dioxo-5,6,7,8-tetrahydropyrido[3,...)
Affinity DataIC50: 350nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303807BDBM303807(4-{[2-(11′-Chloro-2′,5′-dioxo-2&...)
Affinity DataIC50: 370nMAssay Description:o determine the plasma kallikrein inhibition of the substances according to the invention, a biochemical test system is used which utilizes the react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303794BDBM303794(4-{[2-(11′-Chloro-2′,5′-dioxo-2&...)
Affinity DataIC50: 390nMAssay Description:o determine the plasma kallikrein inhibition of the substances according to the invention, a biochemical test system is used which utilizes the react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303783BDBM303783(4-{[2-(10-Chloro-2,5-dioxo-2,5,6,7-tetrahydro-3H-p...)
Affinity DataIC50: 420nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303790BDBM303790(4-{[2-(11-Chloro-2,5-dioxo-5,6,7,8-tetrahydropyrid...)
Affinity DataIC50: 680nMAssay Description:o determine the plasma kallikrein inhibition of the substances according to the invention, a biochemical test system is used which utilizes the react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303786BDBM303786(4-{[(11-Chloro-2,5-dioxo-5,6,7,8-tetrahydropyrido[...)
Affinity DataIC50: 720nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 303808BDBM303808(4-{[2-(11′-Chloro-2′,5′-dioxo-2&...)
Affinity DataIC50: 740nMAssay Description:o determine the plasma kallikrein inhibition of the substances according to the invention, a biochemical test system is used which utilizes the react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

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