Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 918
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Topivert Pharma

US Patent
LigandPNGBDBM255476(US9499486, 1 | US10125100, Example 1 | US9751837, ...)
Affinity DataIC50: 3.30E+3nMAssay Description:ompounds of the invention were tested for inhibition of the human ether a go-go (hERG) channel using IonWorks patch clamp electrophysiology at Essen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Topivert Pharma

US Patent
LigandPNGBDBM298375(US10125100, Example 2 | 4-((4-((4-(3-(5-(tert-Buty...)
Affinity DataIC50: 3.30E+3nMAssay Description:ompounds of the invention were tested for inhibition of the human ether a go-go (hERG) channel using IonWorks patch clamp electrophysiology at Essen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Topivert Pharma

US Patent
LigandPNGBDBM298404(US10125100, Example 17(j) | 4-[[4-[[4-[[5-tert-but...)
Affinity DataIC50: 3.30E+3nMAssay Description:ompounds of the invention were tested for inhibition of the human ether a go-go (hERG) channel using IonWorks patch clamp electrophysiology at Essen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Topivert Pharma

US Patent
LigandPNGBDBM298439(US10125100, Example 22 | 4-((4-((4-(3-(5-(tert-But...)
Affinity DataIC50: 3.70E+3nMAssay Description:ompounds of the invention were tested for inhibition of the human ether a go-go (hERG) channel using IonWorks patch clamp electrophysiology at Essen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Topivert Pharma

US Patent
LigandPNGBDBM298441(US10125100, Example 36 | 4-((4-((4-(3-(5-(tert-But...)
Affinity DataIC50: 1.10E+4nMAssay Description:ompounds of the invention were tested for inhibition of the human ether a go-go (hERG) channel using IonWorks patch clamp electrophysiology at Essen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Topivert Pharma

US Patent
LigandPNGBDBM298444(US10125100, Example 41 | 4-((4-((4-(3-(5-(tert-But...)
Affinity DataIC50: 1.10E+4nMAssay Description:ompounds of the invention were tested for inhibition of the human ether a go-go (hERG) channel using IonWorks patch clamp electrophysiology at Essen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Topivert Pharma

US Patent
LigandPNGBDBM298451(US10125100, Example 43 | Ethyl (4-((4-((4-(3-(5-(t...)
Affinity DataIC50: 1.10E+4nMAssay Description:ompounds of the invention were tested for inhibition of the human ether a go-go (hERG) channel using IonWorks patch clamp electrophysiology at Essen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Topivert Pharma

US Patent
LigandPNGBDBM298446(US10125100, Example 44 | (4-((4-((4-(3-(5-(tert-Bu...)
Affinity DataIC50: 1.10E+4nMAssay Description:ompounds of the invention were tested for inhibition of the human ether a go-go (hERG) channel using IonWorks patch clamp electrophysiology at Essen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Topivert Pharma

US Patent
LigandPNGBDBM298449(US10125100, Example 47 | 2-(2-(2-(4-((4-((4-(3-(5-...)
Affinity DataIC50: 1.10E+4nMAssay Description:ompounds of the invention were tested for inhibition of the human ether a go-go (hERG) channel using IonWorks patch clamp electrophysiology at Essen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Topivert Pharma

US Patent
LigandPNGBDBM298450(US10125100, Example 48 | 4-((4-((4-(3-(5-(tert-But...)
Affinity DataIC50: 1.10E+4nMAssay Description:ompounds of the invention were tested for inhibition of the human ether a go-go (hERG) channel using IonWorks patch clamp electrophysiology at Essen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
Go to US Patent