Compile Data Set for Download or QSAR
Report error Found 60 Enz. Inhib. hit(s) with all data for entry = 822
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293375(US10106510, Compound 39 | Mixture of N- ((1S,2R,4S...)
Affinity DataIC50: 28.6nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293337(US10106510, Compound 6 | Mixture of N- ((1S,2R,4S)...)
Affinity DataIC50: 97.3nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293338(US10106510, Compound 7 | Mixture of N- ((1S,2R,4S)...)
Affinity DataIC50: 170nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293342(US10106510, Compound 11 | 5-cyclopropyl-N-((1r,4r)...)
Affinity DataIC50: 188nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293357(US10106510, Compound 22 | N-((1R,4r)-4-((1r,3R)-3-...)
Affinity DataIC50: 269nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293359(US10106510, Compound 23 | N-((1r,4r)-4-((3- aminop...)
Affinity DataIC50: 342nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293344(US10106510, Compound 13 | N-((1R,4r)-4-((1s,4S)-4-...)
Affinity DataIC50: 352nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293336(US10106510, Compound 5 | N-((1R,4r)-4-((R)-3- amin...)
Affinity DataIC50: 400nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293369(US10106510, Compound 33 | N-((1r,4r)-4-(3-amino- N...)
Affinity DataIC50: 428nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293332(US10106510, Compound 1 | N-((1r,4r)-4-(3- aminobut...)
Affinity DataIC50: 466nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293335(US10106510, Compound 4 | N-((1r,4r)-4-(3- aminopro...)
Affinity DataIC50: 475nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293356(US10106510, Compound 21 | N-((1S,4r)-4-((1S,3R)-3-...)
Affinity DataIC50: 511nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293334(US10106510, Compound 3 | N-((1r,4r)-4-(2-amino- cy...)
Affinity DataIC50: 545nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293368(US10106510, Compound 32 | N-((1S,4r)-4-((1S,3S)-3-...)
Affinity DataIC50: 562nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293363(US10106510, Compound 27 | N-((1r,4r)-4-(3-amino-2-...)
Affinity DataIC50: 567nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293349(US10106510, Compound 16 | N-((1R,4r)-4-((1r,4R)-4-...)
Affinity DataIC50: 606nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293355(US10106510, Compound 20 | N-((1S,4r)-4-((1S,3S)-3-...)
Affinity DataIC50: 625nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293339(US10106510, Compound 8 | N-((1r,4r)-4-(3-amino-2- ...)
Affinity DataIC50: 654nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293351(US10106510, Compound 18 | N-((1r,4r)-4-(3- (benzyl...)
Affinity DataIC50: 671nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293364(US10106510, Compound 28 | N-((1r,4r)-4-((2- aminoe...)
Affinity DataIC50: 853nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293343(US10106510, Compound 12 | 5-cyclopropyl-N-((1r,4r)...)
Affinity DataIC50: 867nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293340(US10106510, Compound 35 | N-((1r,4r)-4-(3-amino- N...)
Affinity DataIC50: 883nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293352(US10106510, Compound 19 | 5-cyclopropyl-N- ((1r,4r...)
Affinity DataIC50: 919nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293367(US10106510, Compound 31 | N-((1S,4r)-4-((S)- 4-ami...)
Affinity DataIC50: 1.08E+3nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293350(US10106510, Compound 17 | 5-cyclopropyl-N-((1r,4r)...)
Affinity DataIC50: 1.15E+3nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293346(US10106510, Compound 14 | N-((1R,4r)-4-((1s,3S)-3-...)
Affinity DataIC50: 1.18E+3nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293362(US10106510, Compound 26 | N-((1S,4r)-4-((1S,3R)-3-...)
Affinity DataIC50: 1.19E+3nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293374(US10106510, Compound 38 | N-((1r,4r)-4-(3-amino- N...)
Affinity DataIC50: 1.20E+3nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293370(US10106510, Compound 34 | N-((1r,4r)-4-((3-amino- ...)
Affinity DataIC50: 1.34E+3nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293366(US10106510, Compound 30 | N-((1R,4r)-4-((R)- 4-ami...)
Affinity DataIC50: 1.69E+3nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293340(US10106510, Compound 35 | N-((1r,4r)-4-(3-amino- N...)
Affinity DataIC50: 2.28E+3nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293333(US10106510, Compound 2 | N-((1S,2R,4S)-4- amino-2-...)
Affinity DataIC50: 2.44E+3nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293360(US10106510, Compound 24 | 5-cyclopropyl-N- ((1r,4r...)
Affinity DataIC50: 2.56E+3nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293365(US10106510, Compound 29 | N-((1r,4r)-4-((2- aminoe...)
Affinity DataIC50: 2.90E+3nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293383(US10106510, Compound 47 | N-((1R,4r)-4-((R)-3- ami...)
Affinity DataIC50: 3.12E+3nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293384(US10106510, Compound 48 | N-((1S,4r)-4-((S)-3- ami...)
Affinity DataIC50: 3.80E+3nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293382(US10106510, Compound 46 | N-((1r,4r)-4-(3- aminopr...)
Affinity DataIC50: 4.34E+3nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293379(US10106510, Compound 43 | N-((1r,4r)-4-(3- aminopr...)
Affinity DataIC50: 4.49E+3nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293396(US10106510, Compound 60 | N-((1r,4r)-4-(3- aminopr...)
Affinity DataIC50: 5.29E+3nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293377(US10106510, Compound 41 | N-((1R,4r)-4-((R)-3- ami...)
Affinity DataIC50: 5.71E+3nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293394(US10106510, Compound 58 | N-((1S,4r)-4-((S)-3- ami...)
Affinity DataIC50: 6.11E+3nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293373(US10106510, Compound 37 | 5-cyclopropyl-N- ((1r,4r...)
Affinity DataIC50: 6.36E+3nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293372(US10106510, Compound 36 | N-((1r,4r)-4-(N- (3-amin...)
Affinity DataIC50: 7.03E+3nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293341(US10106510, Compound 10 | 5-cyclopropyl-N-((1r,4r)...)
Affinity DataIC50: 7.72E+3nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293381(US10106510, Compound 45 | N-((1R,4r)-4-((R)-3- ami...)
Affinity DataIC50: 8.22E+3nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293361(US10106510, Compound 25 | 5-cyclopropyl-N-((1r,4r)...)
Affinity DataIC50: 8.24E+3nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
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TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293392(US10106510, Compound 56 | N-((1R,4r)-4-((R)-3- ami...)
Affinity DataIC50: 9.28E+3nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
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TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293376(US10106510, Compound 40 | N-((1R,4r)-4-((R)-3- ami...)
Affinity DataIC50: 9.69E+3nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
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TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293378(US10106510, Compound 42 | N-((1r,4r)-4-(3- aminopr...)
Affinity DataIC50: 1.08E+4nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
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TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM293390(US10106510, Compound 54 | N-((1S,4r)-4-((S)-3- ami...)
Affinity DataIC50: 1.16E+4nMAssay Description:S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), Tris, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG), and Tris(2-carboxyethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
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