Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 810
TargetGlycogen synthase kinase-3 beta(Human)
Abbvie Deutschland

US Patent
LigandPNGBDBM292097(US10100048, Example 1 | 3-(5-Hydroxy-5,6,7,8-tetra...)
Affinity DataIC50: 100nMT: 2°CAssay Description:Compounds were tested for their ability to inhibit human Glycogen Synthase Kinase-3 beta (hGSK-3β) to phosphorylate biotin-YRRAAVPPSPSLSRHSSPHQ(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2019
Entry Details
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TargetGlycogen synthase kinase-3 beta(Human)
Abbvie Deutschland

US Patent
LigandPNGBDBM292098(US10100048, Example 2.2)
Affinity DataIC50: 100nMT: 2°CAssay Description:Compounds were tested for their ability to inhibit human Glycogen Synthase Kinase-3 beta (hGSK-3β) to phosphorylate biotin-YRRAAVPPSPSLSRHSSPHQ(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2019
Entry Details
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TargetGlycogen synthase kinase-3 beta(Human)
Abbvie Deutschland

US Patent
LigandPNGBDBM292099(US10100048, Example 2 | 2-Oxo-3-(5,6,7,8-tetrahydr...)
Affinity DataIC50: 100nMT: 2°CAssay Description:Compounds were tested for their ability to inhibit human Glycogen Synthase Kinase-3 beta (hGSK-3β) to phosphorylate biotin-YRRAAVPPSPSLSRHSSPHQ(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Abbvie Deutschland

US Patent
LigandPNGBDBM292100(US10100048, Example 3 | 2-Hydroxy-3-(5-oxo-5,6,7,8...)
Affinity DataIC50: 100nMT: 2°CAssay Description:Compounds were tested for their ability to inhibit human Glycogen Synthase Kinase-3 beta (hGSK-3β) to phosphorylate biotin-YRRAAVPPSPSLSRHSSPHQ(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2019
Entry Details
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TargetGlycogen synthase kinase-3 beta(Human)
Abbvie Deutschland

US Patent
LigandPNGBDBM292101(US10100048, Example 4 | 2-Hydroxy-3-(8-hydroxy-5,6...)
Affinity DataIC50: 100nMT: 2°CAssay Description:Compounds were tested for their ability to inhibit human Glycogen Synthase Kinase-3 beta (hGSK-3β) to phosphorylate biotin-YRRAAVPPSPSLSRHSSPHQ(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Abbvie Deutschland

US Patent
LigandPNGBDBM292102(US10100048, Example 5 | 3-(6,7-Dihydro-5H-pyrrolo[...)
Affinity DataIC50: 100nMT: 2°CAssay Description:Compounds were tested for their ability to inhibit human Glycogen Synthase Kinase-3 beta (hGSK-3β) to phosphorylate biotin-YRRAAVPPSPSLSRHSSPHQ(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Abbvie Deutschland

US Patent
LigandPNGBDBM292103(US10100048, Example 6)
Affinity DataIC50: 100nMT: 2°CAssay Description:Compounds were tested for their ability to inhibit human Glycogen Synthase Kinase-3 beta (hGSK-3β) to phosphorylate biotin-YRRAAVPPSPSLSRHSSPHQ(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2019
Entry Details
Go to US Patent