Compile Data Set for Download or QSAR
Report error Found 81 Enz. Inhib. hit(s) with all data for entry = 749
TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160878(US9107923, 48 | US10093655, Example 48 | US1101490...)
Affinity DataKi:  0.571nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160912(US9107923, 1 | US9107923, 2 | US10093655, Example ...)
Affinity DataKi:  3.11nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160861(US9107923, 31 | US10093655, Example 31 | US1101490...)
Affinity DataKi:  3.61nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160894(US9107923, 64 | US10093655, Example 64 | US1101490...)
Affinity DataKi:  4.17nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160871(US9107923, 41 | US10093655, Example 41 | US1101490...)
Affinity DataKi:  5.41nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160883(US10093655, Example 53 | US11014909, Example 53 | ...)
Affinity DataKi:  6.91nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160876(US9107923, 46 | US10093655, Example 46 | US1101490...)
Affinity DataKi:  7.66nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160867(US9107923, 37 | US10093655, Example 37 | US1101490...)
Affinity DataKi:  8.42nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM289097(US10093655, Example 7 | (−)-1,5-Dimethyl-6-(...)
Affinity DataKi:  8.54nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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PDB3D3D Structure (crystal)
TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160884(US9107923, 54 | US9107923, 55 | US10093655, Exampl...)
Affinity DataKi:  9.33nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160873(US9107923, 43 | US10093655, Example 43 | US1101490...)
Affinity DataKi:  9.65nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160880(US9107923, 50 | US10093655, Example 50 | US1101490...)
Affinity DataKi:  10.1nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160922(US11014909, Example 11 | BDBM289101 | US9107923, 1...)
Affinity DataKi:  10.9nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160892(US9107923, 62 | US10093655, Example 62 | US1101490...)
Affinity DataKi:  12.1nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM289111(US10093655, Example 19 | 1,5-Dimethyl-6-(7-{[3-(tr...)
Affinity DataKi:  12.9nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160893(US9107923, 63 | US10093655, Example 63 | US1101490...)
Affinity DataKi:  13.4nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160869(US9107923, 39 | US10093655, Example 39 | US1101490...)
Affinity DataKi:  15nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160912(US9107923, 1 | US9107923, 2 | US10093655, Example ...)
Affinity DataKi:  15.3nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160898(US9107923, 68 | US10093655, Example 68 | US1101490...)
Affinity DataKi:  16.9nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM289104(US10093655, Example 14 | (−)-6-(4-{[3-(Diflu...)
Affinity DataKi:  17.5nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160875(US9107923, 45 | US10093655, Example 45 | US1101490...)
Affinity DataKi:  18.6nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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PDB3D3D Structure (crystal)
TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM289098(US10093655, Example 8 | (+)-1,5-Dimethyl-6-(2-meth...)
Affinity DataKi:  21nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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PDB3D3D Structure (crystal)
TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160891(US9107923, 61 | US10093655, Example 61 | US1101490...)
Affinity DataKi:  23.8nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160884(US9107923, 54 | US9107923, 55 | US10093655, Exampl...)
Affinity DataKi:  24.2nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160895(US9107923, 65 | US10093655, Example 66 | US1101490...)
Affinity DataKi:  26.9nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160887(US9107923, 57 | US10093655, Example 57 | US1101490...)
Affinity DataKi:  30.5nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160868(US9107923, 38 | US10093655, Example 38 | US1101490...)
Affinity DataKi:  31.1nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160908(US9107923, 78 | US10093655, Example 78 | US1101490...)
Affinity DataKi:  32.3nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM289096(US10093655, Example 6 | 6-{4-[(3-Chloropyridin-2-y...)
Affinity DataKi:  33.1nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160895(US9107923, 65 | US10093655, Example 66 | US1101490...)
Affinity DataKi:  34.4nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM289109(US10093655, Example 18 | 6-{4-[(3-Chloropyridin-2-...)
Affinity DataKi:  35.7nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160857(US9107923, 27 | US10093655, Example 27 | US1101490...)
Affinity DataKi:  36.2nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160899(US9107923, 69 | US10093655, Example 69 | US1101490...)
Affinity DataKi:  38.3nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160855(US9107923, 25 | US10093655, Example 25 | US1101490...)
Affinity DataKi:  38.5nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160914(US9107923, 3 | US9107923, 4 | US10093655, Example ...)
Affinity DataKi:  40.6nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160903(US9107923, 73 | US10093655, Example 73 | US1101490...)
Affinity DataKi:  43.4nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM289106(US10093655, Example 16 | (+)-5-(4-{[3-(Difluoromet...)
Affinity DataKi:  44.3nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160853(US9107923, 23 | US10093655, Example 23)
Affinity DataKi:  45.9nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160850(US9107923, 20 | US10093655, Example 20)
Affinity DataKi:  52.7nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM289105(US10093655, Example 15 | (+)-6-(4-{[3-(Difluoromet...)
Affinity DataKi:  54.7nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM289102(US10093655, Example 12 | 6-(4-{[3-(Difluoromethyl)...)
Affinity DataKi:  55.1nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160911(US9107923, 81 | US10093655, Example 81 | US1101490...)
Affinity DataKi:  58nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM289095(US10093655, Example 5 | 6-{4-[(3-Chloropyridin-2-y...)
Affinity DataKi:  58nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM289107(US10093655, Example 17 | (−)-5-(4-{[3-(Diflu...)
Affinity DataKi:  59.1nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160882(US9107923, 52 | US10093655, Example 52 | US1101490...)
Affinity DataKi:  63.1nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160877(US9107923, 47 | US10093655, Example 47 | US1101490...)
Affinity DataKi:  82.3nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM289100(US10093655, Example 10 | (−)-6-{4-[(3-Chloro...)
Affinity DataKi:  82.3nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160870(US9107923, 40 | US10093655, Example 40 | US1101490...)
Affinity DataKi:  82.7nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160852(US9107923, 22 | US10093655, Example 22 | US1101490...)
Affinity DataKi:  82.7nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160888(US9107923, 58 | US10093655, Example 58 | US1101490...)
Affinity DataKi:  86.2nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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