Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 239
TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246818BDBM246818(Cis-11-isobutoxy-10-methoxy-3,3-dimethyl-7-oxo-1,2...)
Affinity DataIC50: 1nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246831BDBM246831(Cis-11-((6-hydroxyhexyl)oxy)-10-methoxy-3,3-dimeth...)
Affinity DataIC50: 1nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246811BDBM246811(cis-10-methoxy-11-(3-methoxypropoxy)-3,3-dimethyl-...)
Affinity DataIC50: 1nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246819BDBM246819(Cis-11-(cyclopropylmethoxy)-10-methoxy-3,3-dimethy...)
Affinity DataIC50: 1nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246850BDBM246850(Cis-10-methoxy-3,3-dimethyl-7-oxo-11-(pyrrolidin-1...)
Affinity DataIC50: 1.60nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246832BDBM246832(Cis-11-((6-((tert-butoxycarbonyl)amino)hexyl)oxy)-...)
Affinity DataIC50: 2nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246829BDBM246829(Cis-10-methoxy-3,3-dimethyl-11-(3-(methylthio)prop...)
Affinity DataIC50: 2nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246835BDBM246835(Cis-10-methoxy-3,3-dimethyl-11-((6-(methylsulfonam...)
Affinity DataIC50: 2nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246817BDBM246817(Cis-10-methoxy-3,3-dimethyl-7-oxo-11-(2,2,2-triflu...)
Affinity DataIC50: 3nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246812BDBM246812(US10053461, 3 | US10053461, 4 | Cis-11-(benzyloxy)...)
Affinity DataIC50: 3nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246812BDBM246812(US10053461, 3 | US10053461, 4 | Cis-11-(benzyloxy)...)
Affinity DataIC50: 3nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246823BDBM246823(Cis-11-(3-hydroxy-2,2-dimethylpropoxy)-10-methoxy-...)
Affinity DataIC50: 3nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246837BDBM246837(cis-13-chloro-12-(3-methoxypropoxy)-2-oxo-2,5a,6,7...)
Affinity DataIC50: 3nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246821BDBM246821(Cis-11-(3-cyanopropoxy)-10-methoxy-3,3-dimethyl-7-...)
Affinity DataIC50: 4nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246820BDBM246820(Cis-10-methoxy-11-(2-methoxyethoxy)-3,3-dimethyl-7...)
Affinity DataIC50: 4nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246816BDBM246816(Cis-10,11-dimethoxy-3,3-dimethyl-7-oxo-1,2,3,3a,7,...)
Affinity DataIC50: 5nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246822BDBM246822(Cis-11-(3-hydroxypropoxy)-10-methoxy-3,3-dimethyl-...)
Affinity DataIC50: 5nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246834BDBM246834(Cis-11-((6-acetamidohexyl)oxy)-10-methoxy-3,3-dime...)
Affinity DataIC50: 6nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246824BDBM246824(Cis-10-methoxy-3,3-dimethyl-11-(3-morpholinopropox...)
Affinity DataIC50: 6nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246827BDBM246827(Cis-11-(4-ethoxy-4-oxobutoxy)-10-methoxy-3,3-dimet...)
Affinity DataIC50: 10nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246810BDBM246810(trans-10-methoxy-11-(3-methoxypropoxy)-3,3-dimethy...)
Affinity DataIC50: 10nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246830BDBM246830(Cis-10-methoxy-3,3-dimethyl-11-(3-(methylsulfonyl)...)
Affinity DataIC50: 17nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246849BDBM246849(Cis-10-methoxy-3,3-dimethyl-7-oxo-11-propyl-1,2,3,...)
Affinity DataIC50: 19nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246833BDBM246833(Cis-11-((6-aminohexyl)oxy)-10-methoxy-3,3-dimethyl...)
Affinity DataIC50: 20nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246848BDBM246848(Cis-10-methoxy-3,3,11-trimethyl-7-oxo-1,2,3,3a,7,1...)
Affinity DataIC50: 20nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246836BDBM246836(trans-13-chloro-12-(3-methoxypropoxy)-2-oxo-2,5a,6...)
Affinity DataIC50: 20nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246826BDBM246826(Cis-10-methoxy-3,3-dimethyl-7-oxo-11-(3-(2-oxopyrr...)
Affinity DataIC50: 25nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246845BDBM246845(cis-11-methoxy-12-(3-methoxypropoxy)-8-oxo-1,3,4,4...)
Affinity DataIC50: 28nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246847BDBM246847(Cis-10-methoxy-3,3,11-trimethyl-7-oxo-1,2,3,3a,7,1...)
Affinity DataIC50: 36nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246841BDBM246841(cis-12-benzyloxy-11-methoxy-8-oxo-1,2,3,4,4a,13b-h...)
Affinity DataIC50: 44nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246815BDBM246815(Cis-11-hydroxy-10-methoxy-3,3-dimethyl-7-oxo-1,2,3...)
Affinity DataIC50: 84nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246844BDBM246844(Trans-11-methoxy-12-(3-methoxypropoxy)-8-oxo-1,3,4...)
Affinity DataIC50: 110nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246840BDBM246840(Trans-12-benzyloxy-11-methoxy-8-oxo-1,2,3,4,4a,13b...)
Affinity DataIC50: 120nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246825BDBM246825(Cis-10-methoxy-3,3-dimethyl-7-oxo-11-(3-(pyrrolidi...)
Affinity DataIC50: 128nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246838BDBM246838(trans-2-((benzyloxy)carbonyl)-11-methoxy-12-(3-met...)
Affinity DataIC50: 152nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246843BDBM246843(cis-11-methoxy-12-(3-methoxypropoxy)-8-oxo-1,3,4,4...)
Affinity DataIC50: 186nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246842BDBM246842(Trans-11-methoxy-12-(3-methoxypropoxy)-8-oxo-1,3,4...)
Affinity DataIC50: 265nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246814BDBM246814((3aR,12bS)-11-(benzyloxy)-10-methoxy-3,3-dimethyl-...)
Affinity DataIC50: 308nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246828BDBM246828(Cis-11-(3-carboxypropoxy)-10-methoxy-3,3-dimethyl-...)
Affinity DataIC50: 505nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246839BDBM246839(cis-2-((benzyloxy)carbonyl)-11-methoxy-12-(3-metho...)
Affinity DataIC50: 564nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetLarge envelope protein(HBV-D)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 246846BDBM246846(Trans-11-methoxy-12-(3-methoxypropoxy)-8-oxo-1,3,4...)
Affinity DataIC50: 2.20E+3nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent