Compile Data Set for Download or QSAR
Report error Found 74 Enz. Inhib. hit(s) with all data for entry = 584
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239030(US9408850, 16 | US10028934, Compound 16 | US959731...)
Affinity DataIC50: 50nMpH: 7.9Assay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239034(US9408850, 23 | US10028934, Compound 23 | US104784...)
Affinity DataIC50: 50nMpH: 7.9Assay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239038(US9408850, 27 | US10028934, Compound 27 | US959731...)
Affinity DataIC50: 50nMpH: 7.9Assay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239026(US9408850, 40 | US10028934, Compound 40 | US959731...)
Affinity DataIC50: 50nMpH: 7.9Assay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239029(US9408850, 15 | US10028934, Compound 15 | US959731...)
Affinity DataIC50: 50nMpH: 7.9Assay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239033(US9408850, 19 | US10028934, Compound 19 | US104784...)
Affinity DataIC50: 50nMpH: 7.9Assay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239040(US9408850, 14 | US10028934, Compound 14 | US959731...)
Affinity DataIC50: 50nMpH: 7.9Assay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239017(US9408850, 11 | US10028934, Compound 11 | US959731...)
Affinity DataIC50: 50nMpH: 7.9Assay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239022(US9408850, 33 | US10028934, Compound 33 | US959731...)
Affinity DataIC50: 50nMpH: 7.9Assay Description:i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239022(US9408850, 33 | US10028934, Compound 33 | US959731...)
Affinity DataIC50: 50nMpH: 7.9Assay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239042(US9408850, 42 | US10028934, Compound 42 | US959731...)
Affinity DataIC50: 50nMpH: 7.9Assay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239023(US9408850, 32 | US10028934, Compound 32 | US959731...)
Affinity DataIC50: 50nMpH: 7.9Assay Description:i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239023(US9408850, 32 | US10028934, Compound 32 | US959731...)
Affinity DataIC50: 50nMpH: 7.9Assay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239043(US9408850, 20 | US10028934, Compound 20 | US959731...)
Affinity DataIC50: 50nMpH: 7.9Assay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239012(US9408850, 10 | US10028934, Compound 10 | US959731...)
Affinity DataIC50: 50nMpH: 7.9Assay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239041(US9408850, 41 | US10028934, Compound 41 | US959731...)
Affinity DataIC50: 52nMpH: 7.9Assay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239043(US9408850, 20 | US10028934, Compound 20 | US959731...)
Affinity DataIC50: 52nMpH: 7.9Assay Description:i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239042(US9408850, 42 | US10028934, Compound 42 | US959731...)
Affinity DataIC50: 55nMpH: 7.9Assay Description:i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239019(US9408850, 22 | US10028934, Compound 22 | US104784...)
Affinity DataIC50: 55nMpH: 7.9Assay Description:i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239019(US9408850, 22 | US10028934, Compound 22 | US104784...)
Affinity DataIC50: 56nMpH: 7.9Assay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239024(US9408850, 34 | US10028934, Compound 34 | US959731...)
Affinity DataIC50: 56nMpH: 7.9Assay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239024(US9408850, 34 | US10028934, Compound 34 | US959731...)
Affinity DataIC50: 58nMpH: 7.9Assay Description:i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239033(US9408850, 19 | US10028934, Compound 19 | US104784...)
Affinity DataIC50: 61nMpH: 7.9Assay Description:i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239028(US9408850, 39 | US10028934, Compound 39 | US959731...)
Affinity DataIC50: 62nMpH: 7.9Assay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239031(US9408850, 17 | US10028934, Compound 17 | US959731...)
Affinity DataIC50: 62nMpH: 7.9Assay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239036(US9408850, 25 | US10028934, Compound 25 | US959731...)
Affinity DataIC50: 74nMpH: 7.9Assay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239029(US9408850, 15 | US10028934, Compound 15 | US959731...)
Affinity DataIC50: 76nMpH: 7.9Assay Description:i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239026(US9408850, 40 | US10028934, Compound 40 | US959731...)
Affinity DataIC50: 88nMpH: 7.9Assay Description:i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239037(US9408850, 26 | US10028934, Compound 26 | US959731...)
Affinity DataIC50: 90nMpH: 7.9Assay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239038(US9408850, 27 | US10028934, Compound 27 | US959731...)
Affinity DataIC50: 91nMpH: 7.9Assay Description:i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239018(US9408850, 21 | US10028934, Compound 21 | US959731...)
Affinity DataIC50: 104nMpH: 7.9Assay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239030(US9408850, 16 | US10028934, Compound 16 | US959731...)
Affinity DataIC50: 106nMpH: 7.9Assay Description:i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239034(US9408850, 23 | US10028934, Compound 23 | US104784...)
Affinity DataIC50: 109nMpH: 7.9Assay Description:i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239017(US9408850, 11 | US10028934, Compound 11 | US959731...)
Affinity DataIC50: 113nMpH: 7.9Assay Description:i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239040(US9408850, 14 | US10028934, Compound 14 | US959731...)
Affinity DataIC50: 118nMpH: 7.9Assay Description:i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239037(US9408850, 26 | US10028934, Compound 26 | US959731...)
Affinity DataIC50: 124nMpH: 7.9Assay Description:i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239018(US9408850, 21 | US10028934, Compound 21 | US959731...)
Affinity DataIC50: 134nMpH: 7.9Assay Description:i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239039(US9408850, 28 | US10028934, Compound 28 | US959731...)
Affinity DataIC50: 136nMpH: 7.9Assay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239031(US9408850, 17 | US10028934, Compound 17 | US959731...)
Affinity DataIC50: 146nMpH: 7.9Assay Description:i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239035(US9408850, 24 | US10028934, Compound 24 | US104784...)
Affinity DataIC50: 162nMpH: 7.9Assay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239025(US9408850, 30 | US10028934, Compound 30 | US959731...)
Affinity DataIC50: 166nMpH: 7.9Assay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239013(US9408850, 2 | US10028934, Compound 2 | US9597317,...)
Affinity DataIC50: 172nMpH: 7.9Assay Description:i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239041(US9408850, 41 | US10028934, Compound 41 | US959731...)
Affinity DataIC50: 180nMpH: 7.9Assay Description:i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239036(US9408850, 25 | US10028934, Compound 25 | US959731...)
Affinity DataIC50: 197nMpH: 7.9Assay Description:i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239011(US9408850, 6 | US10028934, Compound 6 | US9597317,...)
Affinity DataIC50: 248nMpH: 7.9Assay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239010(US9408850, 7 | US10028934, Compound 7 | US9597317,...)
Affinity DataIC50: 249nMpH: 7.9Assay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239035(US9408850, 24 | US10028934, Compound 24 | US104784...)
Affinity DataIC50: 260nMpH: 7.9Assay Description:i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239039(US9408850, 28 | US10028934, Compound 28 | US959731...)
Affinity DataIC50: 306nMpH: 7.9Assay Description:i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239032(US9408850, 18 | US10028934, Compound 18 | US959731...)
Affinity DataIC50: 414nMpH: 7.9Assay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239009(US9408850, 1 | US10028934, Compound 1 | US9597317,...)
Affinity DataIC50: 428nMpH: 7.9Assay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

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