Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50008436
TargetProthrombin(Human)
Nv Organon Scientific Development Group

Curated by ChEMBL
LigandPNGBDBM50073322(((R)-2-Cyclohexyl-1-{cyclopentyl-[(3-guanidino-pro...)
Affinity DataIC50: 110nMAssay Description:The inhibitory activity against thrombin (IIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Nv Organon Scientific Development Group

Curated by ChEMBL
LigandPNGBDBM50073311(((R)-2-Cyclohexyl-1-{cyclopentyl-[(3-guanidino-3-o...)
Affinity DataIC50: 240nMAssay Description:The inhibitory activity against thrombin (IIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Nv Organon Scientific Development Group

Curated by ChEMBL
LigandPNGBDBM50073320(((R)-2-Cyclohexyl-1-{cyclopentyl-[(3-guanidino-3-o...)
Affinity DataIC50: 240nMAssay Description:The inhibitory activity against thrombin (IIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Nv Organon Scientific Development Group

Curated by ChEMBL
LigandPNGBDBM50073323({(R)-1-Cyclohexylmethyl-2-[(S)-2-(3-guanidino-3-ox...)
Affinity DataIC50: 1.10E+3nMAssay Description:The inhibitory activity against thrombin (IIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Nv Organon Scientific Development Group

Curated by ChEMBL
LigandPNGBDBM50073316(CHEMBL114715 | {[(1R)-2-((2S)-2-{[(3-{[AMINO(IMINO...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of thrombin (IIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Nv Organon Scientific Development Group

Curated by ChEMBL
LigandPNGBDBM50073313(N-(3-Guanidino-3-oxo-propyl)-2-(6-methyl-2-oxo-3-p...)
Affinity DataIC50: 1.90E+3nMAssay Description:The inhibitory activity against thrombin (IIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Nv Organon Scientific Development Group

Curated by ChEMBL
LigandPNGBDBM50073319((S)-1-(9-Hydroxy-9H-fluorene-9-carbonyl)-pyrrolidi...)
Affinity DataIC50: 6.00E+3nMAssay Description:The inhibitory activity against thrombin (IIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Nv Organon Scientific Development Group

Curated by ChEMBL
LigandPNGBDBM50073315((S)-1-((R)-3-Cyclohexyl-2-ethanesulfonylamino-prop...)
Affinity DataIC50: 1.00E+4nMAssay Description:The inhibitory activity against thrombin (IIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Nv Organon Scientific Development Group

Curated by ChEMBL
LigandPNGBDBM50073312(((R)-1-{[(5-Amino-pentylcarbamoyl)-methyl]-cyclope...)
Affinity DataIC50: 1.35E+4nMAssay Description:The inhibitory activity against thrombin (IIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Nv Organon Scientific Development Group

Curated by ChEMBL
LigandPNGBDBM50073324(N-(3-Guanidino-3-oxo-propyl)-2-((S)-2-oxo-3-phenyl...)
Affinity DataIC50: 7.30E+4nMAssay Description:The inhibitory activity against thrombin (IIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Nv Organon Scientific Development Group

Curated by ChEMBL
LigandPNGBDBM50073310(((R)-2-Cyclohexyl-1-{cyclopentyl-[(2-piperidin-4-y...)
Affinity DataIC50: 7.40E+4nMAssay Description:The inhibitory activity against thrombin (IIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Nv Organon Scientific Development Group

Curated by ChEMBL
LigandPNGBDBM50073317([(R)-1-({[3-(5-Amino-2H-[1,2,4]triazol-3-yl)-propy...)
Affinity DataIC50: 1.00E+5nMAssay Description:The inhibitory activity against thrombin (IIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Nv Organon Scientific Development Group

Curated by ChEMBL
LigandPNGBDBM50073321([(R)-1-({[2-(5-Amino-2H-[1,2,4]triazol-3-yl)-ethyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:The inhibitory activity against thrombin (IIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Nv Organon Scientific Development Group

Curated by ChEMBL
LigandPNGBDBM50073318(((R)-2-Cyclohexyl-1-{cyclopentyl-[(4-guanidinocarb...)
Affinity DataIC50: 1.00E+5nMAssay Description:The inhibitory activity against thrombin (IIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Nv Organon Scientific Development Group

Curated by ChEMBL
LigandPNGBDBM50073314([(R)-2-Cyclohexyl-1-(cyclopentyl-{[(piperidin-4-yl...)
Affinity DataIC50: 1.33E+5nMAssay Description:The inhibitory activity against thrombin (IIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Nv Organon Scientific Development Group

Curated by ChEMBL
LigandPNGBDBM50073316(CHEMBL114715 | {[(1R)-2-((2S)-2-{[(3-{[AMINO(IMINO...)
Affinity DataKi:  15nMAssay Description:The inhibitory activity against thrombin (IIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Nv Organon Scientific Development Group

Curated by ChEMBL
LigandPNGBDBM50073316(CHEMBL114715 | {[(1R)-2-((2S)-2-{[(3-{[AMINO(IMINO...)
Affinity DataKi:  675nMAssay Description:The inhibitory activity against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed