Compile Data Set for Download or QSAR
Report error Found 54 Enz. Inhib. hit(s) with all data for entry = 50008329
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM17283((2S)-3-(7-carbamimidoylnaphthalen-2-yl)-2-(4-{[(3S...)
Affinity DataIC50: 41nMAssay Description:Compound was tested for the inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072442({(3-Carbamimidoyl-phenyl)-[2-(2'-sulfamoyl-bipheny...)
Affinity DataKi:  0.530nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072448({(3-Carbamimidoyl-phenyl)-[3-(2'-sulfamoyl-bipheny...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072444({(3-Carbamimidoyl-phenyl)-[2-(2'-sulfamoyl-bipheny...)
Affinity DataKi:  2.10nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072445(CHEMBL139063 | CHEMBL279628 | [3-(3-Carbamimidoyl-...)
Affinity DataKi:  6.30nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072435({(3-Carbamimidoyl-phenyl)-[3-(2'-sulfamoyl-bipheny...)
Affinity DataKi:  6.70nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072434({(3-Carbamimidoyl-phenyl)-[3-(2'-sulfamoyl-bipheny...)
Affinity DataKi:  7.5nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072437({(3-Carbamimidoyl-phenyl)-[2-(2'-sulfamoyl-bipheny...)
Affinity DataKi:  10nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072440(3-{(2-Methoxy-ethyl)-[3-(2'-sulfamoyl-biphenyl-4-y...)
Affinity DataKi:  11nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072449({(3-Carbamimidoyl-phenyl)-[3-(2'-sulfamoyl-bipheny...)
Affinity DataKi:  12nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072450(3-{(2-Oxo-propyl)-[3-(2'-sulfamoyl-biphenyl-4-yl)-...)
Affinity DataKi:  16nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072436(3-{(2-Phenoxy-ethyl)-[3-(2'-sulfamoyl-biphenyl-4-y...)
Affinity DataKi:  16nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072438(3-{(2-Hydroxy-ethyl)-[3-(2'-sulfamoyl-biphenyl-4-y...)
Affinity DataKi:  17nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072446(2-{(3-Carbamimidoyl-phenyl)-[3-(2'-sulfamoyl-biphe...)
Affinity DataKi:  19nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072442({(3-Carbamimidoyl-phenyl)-[2-(2'-sulfamoyl-bipheny...)
Affinity DataKi:  19nMAssay Description:Inhibition of serine protease trypsin enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072439({(3-Carbamimidoyl-phenyl)-[2-(2'-sulfamoyl-bipheny...)
Affinity DataKi:  21nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062035(5-(4-Carbamimidoyl-phenyl)-3-(3-carbamimidoyl-phen...)
Affinity DataKi:  34nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072433({(3-Carbamimidoyl-phenyl)-[2-(2'-sulfamoyl-bipheny...)
Affinity DataKi:  37nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072448({(3-Carbamimidoyl-phenyl)-[3-(2'-sulfamoyl-bipheny...)
Affinity DataKi:  39nMAssay Description:Inhibition of serine protease trypsin enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072447(3-[2-(2'-Sulfamoyl-biphenyl-4-yl)-ethanesulfonylam...)
Affinity DataKi:  51nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072444({(3-Carbamimidoyl-phenyl)-[2-(2'-sulfamoyl-bipheny...)
Affinity DataKi:  52nMAssay Description:Inhibition of serine protease trypsin enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072437({(3-Carbamimidoyl-phenyl)-[2-(2'-sulfamoyl-bipheny...)
Affinity DataKi:  56nMAssay Description:Inhibition of serine protease trypsin enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072434({(3-Carbamimidoyl-phenyl)-[3-(2'-sulfamoyl-bipheny...)
Affinity DataKi:  74nMAssay Description:Inhibition of serine protease trypsin enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072435({(3-Carbamimidoyl-phenyl)-[3-(2'-sulfamoyl-bipheny...)
Affinity DataKi:  77nMAssay Description:Inhibition of serine protease trypsin enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072443(3-[3-(2'-Sulfamoyl-biphenyl-4-yl)-propylamino]-ben...)
Affinity DataKi:  83nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072441(CHEMBL323060 | CHEMBL92988 | [3-(3-Carbamimidoyl-p...)
Affinity DataKi:  94nMAssay Description:Inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072439({(3-Carbamimidoyl-phenyl)-[2-(2'-sulfamoyl-bipheny...)
Affinity DataKi:  180nMAssay Description:Inhibition of serine protease trypsin enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072442({(3-Carbamimidoyl-phenyl)-[2-(2'-sulfamoyl-bipheny...)
Affinity DataKi:  200nMAssay Description:Inhibition of serine protease thrombin enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072448({(3-Carbamimidoyl-phenyl)-[3-(2'-sulfamoyl-bipheny...)
Affinity DataKi:  200nMAssay Description:Inhibition of serine protease thrombin enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072433({(3-Carbamimidoyl-phenyl)-[2-(2'-sulfamoyl-bipheny...)
Affinity DataKi:  220nMAssay Description:Inhibition of serine protease trypsin enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072448({(3-Carbamimidoyl-phenyl)-[3-(2'-sulfamoyl-bipheny...)
Affinity DataKi:  300nMAssay Description:Compound was tested for the inhibition of serine protease plasmin enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072444({(3-Carbamimidoyl-phenyl)-[2-(2'-sulfamoyl-bipheny...)
Affinity DataKi:  300nMAssay Description:Inhibition of serine protease thrombin enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072436(3-{(2-Phenoxy-ethyl)-[3-(2'-sulfamoyl-biphenyl-4-y...)
Affinity DataKi:  300nMAssay Description:Inhibition of serine protease thrombin enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072440(3-{(2-Methoxy-ethyl)-[3-(2'-sulfamoyl-biphenyl-4-y...)
Affinity DataKi:  330nMAssay Description:Inhibition of serine protease trypsin enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072450(3-{(2-Oxo-propyl)-[3-(2'-sulfamoyl-biphenyl-4-yl)-...)
Affinity DataKi:  360nMAssay Description:Inhibition of serine protease trypsin enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072437({(3-Carbamimidoyl-phenyl)-[2-(2'-sulfamoyl-bipheny...)
Affinity DataKi:  400nMAssay Description:Inhibition of serine protease thrombin enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072449({(3-Carbamimidoyl-phenyl)-[3-(2'-sulfamoyl-bipheny...)
Affinity DataKi:  470nMAssay Description:Inhibition of serine protease trypsin enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072434({(3-Carbamimidoyl-phenyl)-[3-(2'-sulfamoyl-bipheny...)
Affinity DataKi:  500nMAssay Description:Inhibition of serine protease thrombin enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072435({(3-Carbamimidoyl-phenyl)-[3-(2'-sulfamoyl-bipheny...)
Affinity DataKi:  600nMAssay Description:Inhibition of serine protease thrombin enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072438(3-{(2-Hydroxy-ethyl)-[3-(2'-sulfamoyl-biphenyl-4-y...)
Affinity DataKi:  710nMAssay Description:Inhibition of serine protease trypsin enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072446(2-{(3-Carbamimidoyl-phenyl)-[3-(2'-sulfamoyl-biphe...)
Affinity DataKi:  820nMAssay Description:Inhibition of serine protease trypsin enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072443(3-[3-(2'-Sulfamoyl-biphenyl-4-yl)-propylamino]-ben...)
Affinity DataKi:  850nMAssay Description:Inhibition of serine protease trypsin enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072440(3-{(2-Methoxy-ethyl)-[3-(2'-sulfamoyl-biphenyl-4-y...)
Affinity DataKi:  900nMAssay Description:Inhibition of serine protease thrombin enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072450(3-{(2-Oxo-propyl)-[3-(2'-sulfamoyl-biphenyl-4-yl)-...)
Affinity DataKi:  900nMAssay Description:Inhibition of serine protease thrombin enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072449({(3-Carbamimidoyl-phenyl)-[3-(2'-sulfamoyl-bipheny...)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of serine protease thrombin enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072447(3-[2-(2'-Sulfamoyl-biphenyl-4-yl)-ethanesulfonylam...)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of serine protease trypsin enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072438(3-{(2-Hydroxy-ethyl)-[3-(2'-sulfamoyl-biphenyl-4-y...)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of serine protease thrombin enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072446(2-{(3-Carbamimidoyl-phenyl)-[3-(2'-sulfamoyl-biphe...)
Affinity DataKi:  3.50E+3nMAssay Description:Inhibition of serine protease thrombin enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072448({(3-Carbamimidoyl-phenyl)-[3-(2'-sulfamoyl-bipheny...)
Affinity DataKi:  4.20E+3nMAssay Description:Compound was tested for the inhibition of serine protease factor VIIa enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072443(3-[3-(2'-Sulfamoyl-biphenyl-4-yl)-propylamino]-ben...)
Affinity DataKi:  6.10E+3nMAssay Description:Inhibition of serine protease thrombin enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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