Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50048444
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandPNGBDBM14775(3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of PDE4 from guinea pig macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandPNGBDBM14775(3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of Phosphodiesterase 4 (PDE4) from guinea pig macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandPNGBDBM50216232(CHEMBL93823)
Affinity DataIC50: 2nMAssay Description:Inhibition of PDE4 from guinea pig macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandPNGBDBM50216233(CHEMBL330055)
Affinity DataIC50: 23nMAssay Description:Inhibition of PDE4 from guinea pig macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandPNGBDBM50216234(CHEMBL89931)
Affinity DataIC50: 25nMAssay Description:Inhibition of PDE4 from guinea pig macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandPNGBDBM50216229(CHEMBL329556)
Affinity DataIC50: 27nMAssay Description:Inhibition of PDE4 from guinea pig macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandPNGBDBM50216293(CHEMBL94009)
Affinity DataIC50: 28nMAssay Description:Inhibition of Phosphodiesterase 4 (PDE4) from guinea pig macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandPNGBDBM50216294(CHEMBL449708)
Affinity DataIC50: 42nMAssay Description:Inhibition of PDE4 from guinea pig macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandPNGBDBM50216228(CHEMBL94255)
Affinity DataIC50: 45nMAssay Description:Inhibition of Phosphodiesterase 4 (PDE4) from guinea pig macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandPNGBDBM50216231(CHEMBL329155)
Affinity DataIC50: 100nMAssay Description:Inhibition of PDE4 from guinea pig macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50216230(CHEMBL93327)
Affinity DataIC50: 450nMAssay Description:Inhibition of PDE4 from guinea pig macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
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Curated by ChEMBL
LigandPNGBDBM23620(Dipyridamine | SMR000058382 | MLS000028420 | CHEMB...)
Affinity DataIC50: 500nMAssay Description:Inhibition of Phosphodiesterase 4 (PDE4) from guinea pig macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50216227(CHEMBL329365)
Affinity DataIC50: 540nMAssay Description:Inhibition of PDE4 from guinea pig macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50216226(CHEMBL329023)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of PDE4 from guinea pig macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM14775(3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-...)
Affinity DataKi:  1nMAssay Description:Inhibition of Rolipram binding to Phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)