Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50008236
LigandPNGBDBM50071702(1-[4-(8-Chloro-5,11-dihydro-10-thia-4-aza-dibenzo[...)
Affinity DataIC50: 32nMAssay Description:In vitro FPT potency by measuring the ability to inhibit the transfer of [3H]farnesyl from farnesyl pyrophosphate to H-Ras-CLVS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50071702(1-[4-(8-Chloro-5,11-dihydro-10-thia-4-aza-dibenzo[...)
Affinity DataIC50: 32nMAssay Description:In vitro FPT potency by measuring the ability to inhibit the transfer of [3H]farnesyl from farnesyl pyrophosphate to H-Ras-CLVS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50061441(1-[4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohept...)
Affinity DataIC50: 36nMAssay Description:In vitro FPT potency by measuring the ability to inhibit the transfer of [3H]farnesyl from farnesyl pyrophosphate to H-Ras-CLVS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50071703(Cyanoguanidine derivative | CHEMBL311434)
Affinity DataIC50: 38nMAssay Description:In vitro FPT potency by measuring the ability to inhibit the transfer of [3H]farnesyl from farnesyl pyrophosphate to H-Ras-CLVS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50071700(Cyanoguanidine derivative | CHEMBL81889)
Affinity DataIC50: 43nMAssay Description:In vitro FPT potency by measuring the ability to inhibit the transfer of [3H]farnesyl from farnesyl pyrophosphate to H-Ras-CLVS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50071699(Cyanoguanidine derivative | CHEMBL313090)
Affinity DataIC50: 61nMAssay Description:In vitro FPT potency by measuring the ability to inhibit the transfer of [3H]farnesyl from farnesyl pyrophosphate to H-Ras-CLVS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50071710(1-[4-(8-Chloro-5,11-dihydro-10-thia-4-aza-dibenzo[...)
Affinity DataIC50: 79nMAssay Description:In vitro FPT potency by measuring the ability to inhibit the transfer of [3H]farnesyl from farnesyl pyrophosphate to H-Ras-CLVS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50071712(1-[4-(2-Bromo-8-chloro-11H-10-oxa-4-aza-dibenzo[a,...)
Affinity DataIC50: 110nMAssay Description:In vitro FPT potency by measuring the ability to inhibit the transfer of [3H]farnesyl from farnesyl pyrophosphate to H-Ras-CLVS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50071718(Cyanoguanidine derivative | CHEMBL421722)
Affinity DataIC50: 140nMAssay Description:In vitro FPT potency by measuring the ability to inhibit the transfer of [3H]farnesyl from farnesyl pyrophosphate to H-Ras-CLVS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50071709(Cyanoguanidine derivative | CHEMBL87345)
Affinity DataIC50: 140nMAssay Description:In vitro FPT potency by measuring the ability to inhibit the transfer of [3H]farnesyl from farnesyl pyrophosphate to H-Ras-CLVS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50071715(1-[4-(8-Chloro-11H-10-thia-4-aza-dibenzo[a,d]cyclo...)
Affinity DataIC50: 190nMAssay Description:In vitro FPT potency by measuring the ability to inhibit the transfer of [3H]farnesyl from farnesyl pyrophosphate to H-Ras-CLVS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM14454(1-(4-{13-chloro-4-azatricyclo[9.4.0.0^{3,8}]pentad...)
Affinity DataIC50: 250nMAssay Description:In vitro FPT potency by measuring the ability to inhibit the transfer of [3H]farnesyl from farnesyl pyrophosphate to H-Ras-CLVS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50071698(1-[4-(8-Chloro-11H-10-thia-4-aza-dibenzo[a,d]cyclo...)
Affinity DataIC50: 520nMAssay Description:In vitro FPT potency by measuring the ability to inhibit the transfer of [3H]farnesyl from farnesyl pyrophosphate to H-Ras-CLVS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50071705(1-[4-(8-Chloro-10,10-dioxo-10,11-dihydro-10lambda*...)
Affinity DataIC50: 560nMAssay Description:In vitro FPT potency by measuring the ability to inhibit the transfer of [3H]farnesyl from farnesyl pyrophosphate to H-Ras-CLVS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50071716(1-[4-(8-Chloro-11H-10-thia-4-aza-dibenzo[a,d]cyclo...)
Affinity DataIC50: 590nMAssay Description:In vitro FPT potency by measuring the ability to inhibit the transfer of [3H]farnesyl from farnesyl pyrophosphate to H-Ras-CLVS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50071711(1-[4-(8-Chloro-11H-10-thia-4-aza-dibenzo[a,d]cyclo...)
Affinity DataIC50: 620nMAssay Description:In vitro FPT potency by measuring the ability to inhibit the transfer of [3H]farnesyl from farnesyl pyrophosphate to H-Ras-CLVS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50071714(1-[4-(8-Chloro-10-methyl-10,11-dihydro-5H-4,10-dia...)
Affinity DataIC50: 840nMAssay Description:In vitro FPT potency by measuring the ability to inhibit the transfer of [3H]farnesyl from farnesyl pyrophosphate to H-Ras-CLVS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50071708(4-{2-[4-(8-Chloro-11H-10-thia-4-aza-dibenzo[a,d]cy...)
Affinity DataIC50: 920nMAssay Description:In vitro FPT potency by measuring the ability to inhibit the transfer of [3H]farnesyl from farnesyl pyrophosphate to H-Ras-CLVS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50071720(1-[4-(8-Chloro-10,10-dioxo-10,11-dihydro-5H-10lamb...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro FPT potency by measuring the ability to inhibit the transfer of [3H]farnesyl from farnesyl pyrophosphate to H-Ras-CLVS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM14454(1-(4-{13-chloro-4-azatricyclo[9.4.0.0^{3,8}]pentad...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of Ras processing in COS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50071701(1-[4-(8-Chloro-5,11-dihydro-10-thia-4-aza-dibenzo[...)
Affinity DataIC50: 1.10E+3nMAssay Description:In vitro FPT potency by measuring the ability to inhibit the transfer of [3H]farnesyl from farnesyl pyrophosphate to H-Ras-CLVS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50071704(4-{2-[4-(8-Chloro-5,11-dihydro-10-thia-4-aza-diben...)
Affinity DataIC50: 1.12E+3nMAssay Description:In vitro FPT potency by measuring the ability to inhibit the transfer of [3H]farnesyl from farnesyl pyrophosphate to H-Ras-CLVS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50071717(1-[4-(8-Chloro-11H-10-oxa-4-aza-dibenzo[a,d]cycloh...)
Affinity DataIC50: 1.52E+3nMAssay Description:In vitro FPT potency by measuring the ability to inhibit the transfer of [3H]farnesyl from farnesyl pyrophosphate to H-Ras-CLVS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50071700(Cyanoguanidine derivative | CHEMBL81889)
Affinity DataIC50: 1.70E+3nMAssay Description:In vitro inhibition of Ras processing in COS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50071706(1-[4-(8-Chloro-11H-10-thia-4-aza-dibenzo[a,d]cyclo...)
Affinity DataIC50: 1.79E+3nMAssay Description:In vitro FPT potency by measuring the ability to inhibit the transfer of [3H]farnesyl from farnesyl pyrophosphate to H-Ras-CLVS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50071707(1-[4-(8-Chloro-5,11-dihydro-10-thia-4-aza-dibenzo[...)
Affinity DataIC50: 2.10E+3nMAssay Description:In vitro FPT potency by measuring the ability to inhibit the transfer of [3H]farnesyl from farnesyl pyrophosphate to H-Ras-CLVS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50071713(1-[4-(8-Chloro-10-methyl-10,11-dihydro-5H-4,10-dia...)
Affinity DataIC50: 2.70E+3nMAssay Description:In vitro FPT potency by measuring the ability to inhibit the transfer of [3H]farnesyl from farnesyl pyrophosphate to H-Ras-CLVS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50071719(1-[4-(8-Chloro-10,10-dioxo-10,11-dihydro-5H-10lamb...)
Affinity DataIC50: 3.40E+3nMAssay Description:In vitro FPT potency by measuring the ability to inhibit the transfer of [3H]farnesyl from farnesyl pyrophosphate to H-Ras-CLVS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50061441(1-[4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohept...)
Affinity DataIC50: 3.70E+3nMAssay Description:In vitro inhibition of Ras processing in COS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50071708(4-{2-[4-(8-Chloro-11H-10-thia-4-aza-dibenzo[a,d]cy...)
Affinity DataIC50: 3.80E+3nMAssay Description:In vitro inhibition of Ras processing in COS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50071715(1-[4-(8-Chloro-11H-10-thia-4-aza-dibenzo[a,d]cyclo...)
Affinity DataIC50: 4.20E+3nMAssay Description:In vitro inhibition of Ras processing in COS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50071711(1-[4-(8-Chloro-11H-10-thia-4-aza-dibenzo[a,d]cyclo...)
Affinity DataIC50: 5.00E+3nMAssay Description:In vitro inhibition of Ras processing in COS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50071698(1-[4-(8-Chloro-11H-10-thia-4-aza-dibenzo[a,d]cyclo...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of Ras processing in COS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50071710(1-[4-(8-Chloro-5,11-dihydro-10-thia-4-aza-dibenzo[...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of Ras processing in COS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50071713(1-[4-(8-Chloro-10-methyl-10,11-dihydro-5H-4,10-dia...)
Affinity DataIC50: 2.00E+4nMAssay Description:In vitro inhibition of Ras processing in COS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed