Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50008118
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50070824(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-[3-(4-ch...)
Affinity DataKi:  0.120nMAssay Description:Compound was evaluated to inhibit the thrombin enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50067796(L-374087 | N-(6-Amino-2-methyl-pyridin-3-ylmethyl)...)
Affinity DataKi:  0.5nMAssay Description:Compound was evaluated to inhibit the thrombin enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50070823(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-(2-oxo-3...)
Affinity DataKi:  0.850nMAssay Description:Compound was evaluated to inhibit the thrombin enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50070827(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-[3-(4-ch...)
Affinity DataKi:  2.60nMAssay Description:Compound was evaluated to inhibit the thrombin enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50070825(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-[3-(4-ch...)
Affinity DataKi:  4nMAssay Description:Compound was evaluated to inhibit the thrombin enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50070826(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-(2-oxo-3...)
Affinity DataKi:  12nMAssay Description:Compound was evaluated to inhibit the thrombin enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50070828(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-(6-cyclo...)
Affinity DataKi:  16nMAssay Description:Compound was evaluated to inhibit the thrombin enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069192(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-(2-oxo-3...)
Affinity DataKi:  26nMAssay Description:Compound was evaluated to inhibit the thrombin enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50070823(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-(2-oxo-3...)
Affinity DataKi:  1.40E+3nMAssay Description:Compound was evaluated to inhibit the trypsin enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50070828(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-(6-cyclo...)
Affinity DataKi:  1.70E+3nMAssay Description:Compound was evaluated to inhibit the trypsin enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50070825(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-[3-(4-ch...)
Affinity DataKi:  1.90E+3nMAssay Description:Compound was evaluated to inhibit the trypsin enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50070826(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-(2-oxo-3...)
Affinity DataKi:  2.50E+3nMAssay Description:Compound was evaluated to inhibit the trypsin enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50070824(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-[3-(4-ch...)
Affinity DataKi:  2.60E+3nMAssay Description:Compound was evaluated to inhibit the trypsin enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50067796(L-374087 | N-(6-Amino-2-methyl-pyridin-3-ylmethyl)...)
Affinity DataKi:  3.20E+3nMAssay Description:Compound was evaluated to inhibit the trypsin enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50070827(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-[3-(4-ch...)
Affinity DataKi:  3.40E+3nMAssay Description:Compound was evaluated to inhibit the trypsin enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069192(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-(2-oxo-3...)
Affinity DataKi:  2.00E+4nMAssay Description:Compound was evaluated to inhibit the trypsin enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed