Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50034931
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Universidad De Valencia

Curated by ChEMBL
LigandPNGBDBM50250926(ZM-230487 | 1-ethyl-6-((3-fluoro-5-(4-methoxytetra...)
Affinity DataIC50: 60nMAssay Description:Inhibitory concentration required against 5-lipoxygenase activity in intact cells of human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Universidad De Valencia

Curated by ChEMBL
LigandPNGBDBM50250926(ZM-230487 | 1-ethyl-6-((3-fluoro-5-(4-methoxytetra...)
Affinity DataIC50: 90nMAssay Description:Inhibitory concentration required against 5-lipoxygenase activity in cytosolic fractions of human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Universidad De Valencia

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | NS398 | NS-398 | N-(2-Cyclohexyloxy-4...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibitory concentration required against COX-2 activity in intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Universidad De Valencia

Curated by ChEMBL
LigandPNGBDBM50070261((E)-3-(2-Chloro-quinolin-3-yl)-1-(2,4-dimethyl-fur...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibitory concentration required against 5-lipoxygenase activity in intact cells of human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Universidad De Valencia

Curated by ChEMBL
LigandPNGBDBM50070263((E)-3-(2-Chloro-quinolin-3-yl)-1-(4-fluoro-phenyl)...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibitory concentration required against 5-lipoxygenase activity in intact cells of human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Universidad De Valencia

Curated by ChEMBL
LigandPNGBDBM50070260((E)-1-(3,4-Dichloro-phenyl)-3-furan-2-yl-propenone...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibitory concentration required against 5-lipoxygenase activity in intact cells of human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Universidad De Valencia

Curated by ChEMBL
LigandPNGBDBM50070259((E)-1-(4-Bromo-phenyl)-3-(2,3-dimethoxy-phenyl)-pr...)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibitory concentration required against 5-lipoxygenase activity in intact cells of human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed