Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50007985
TargetSodium-dependent dopamine transporter(Rat)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM22167(GBR-12935 | CHEMBL26320 | CHEMBL434080 | 1-[2-(dip...)
Affinity DataIC50: 3.70nMAssay Description:Compound was tested for its ability to inhibit the uptake of [3H]dopamine in DAT (dopamine transporter system) expressing cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM22165(Vanoxerine | CHEMBL542933 | GBR-12909 | CHEMBL5438...)
Affinity DataIC50: 4.30nMAssay Description:Compound was tested for its ability to inhibit the uptake of [3H]dopamine in DAT (dopamine transporter system) expressing cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent serotonin transporter(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM22167(GBR-12935 | CHEMBL26320 | CHEMBL434080 | 1-[2-(dip...)
Affinity DataIC50: 289nMAssay Description:Compound was tested for its ability to inhibit the uptake of Serotonin in Serotonin transporter systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM22167(GBR-12935 | CHEMBL26320 | CHEMBL434080 | 1-[2-(dip...)
Affinity DataIC50: 1.26E+3nMAssay Description:Compound was tested for its ability to inhibit the uptake of Norepinephrine in Norepinephrine transporter systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed