Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50007958
TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069650(5-({[(S)-2-(3-tert-Butyl-5-methyl-benzyloxy)-1-phe...)
Affinity DataIC50: 0.420nMAssay Description:Affinity towards hNK1 receptor by displacement of [125I]- Substance P from hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069642(5-({[(S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-p...)
Affinity DataIC50: 0.430nMAssay Description:Affinity towards hNK1 receptor by displacement of [125I]- Substance P from hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069659(5-({[(S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-p...)
Affinity DataIC50: 0.800nMAssay Description:Affinity towards hNK1 receptor by displacement of [125I]- Substance P from hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069647([(S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-pheny...)
Affinity DataIC50: 1.40nMAssay Description:Affinity towards hNK1 receptor by displacement of [125I]- Substance P from hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069656(5-({[(S)-2-(3,5-Dichloro-benzyloxy)-1-phenyl-ethyl...)
Affinity DataIC50: 1.5nMAssay Description:Affinity towards hNK1 receptor by displacement of [125I]- Substance P from hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069646(5-({[(S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-p...)
Affinity DataIC50: 2nMAssay Description:Affinity towards hNK1 receptor by displacement of [125I]- Substance P from hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069658(5-({[(S)-2-(3-Chloro-5-methyl-benzyloxy)-1-phenyl-...)
Affinity DataIC50: 2.20nMAssay Description:Affinity towards hNK1 receptor by displacement of [125I]- Substance P from hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069643(5-{[(S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-ph...)
Affinity DataIC50: 2.40nMAssay Description:Affinity towards hNK1 receptor by displacement of [125I]- Substance P from hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069649([(S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-pheny...)
Affinity DataIC50: 5nMAssay Description:Affinity towards hNK1 receptor by displacement of [125I]- Substance P from hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069657(2-{[(S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-ph...)
Affinity DataIC50: 5.80nMAssay Description:Affinity towards hNK1 receptor by displacement of [125I]- Substance P from hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069644(2-[(S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-phe...)
Affinity DataIC50: 8nMAssay Description:Affinity towards hNK1 receptor by displacement of [125I]- Substance P from hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069655([(S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-pheny...)
Affinity DataIC50: 10nMAssay Description:Affinity towards hNK1 receptor by displacement of [125I]- Substance P from hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069648((S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-phenyl...)
Affinity DataIC50: 13nMAssay Description:Affinity towards hNK1 receptor by displacement of [125I]- Substance P from hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069654([(S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-pheny...)
Affinity DataIC50: 13nMAssay Description:Affinity towards hNK1 receptor by displacement of [125I]- Substance P from hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069652([(S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-pheny...)
Affinity DataIC50: 15nMAssay Description:Affinity towards hNK1 receptor by displacement of [125I]- Substance P from hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069645([(S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-pheny...)
Affinity DataIC50: 16nMAssay Description:Affinity towards hNK1 receptor by displacement of [125I]- Substance P from hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069651([(S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-pheny...)
Affinity DataIC50: 23nMAssay Description:Affinity towards hNK1 receptor by displacement of [125I]- Substance P from hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069653([(S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-pheny...)
Affinity DataIC50: 70nMAssay Description:Affinity towards hNK1 receptor by displacement of [125I]- Substance P from hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069642(5-({[(S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-p...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity for Tachykinin receptor 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069642(5-({[(S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-p...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity for Tachykinin receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed