Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 1529
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM11929(2-N-[(4-methylphenyl)methyl]thiophene-2,5-disulfon...)
Affinity DataKd:  0.460nMpH: 7.4 T: 2°CAssay Description:The binding of test compounds to purified human erythrocyte carbonic anhydrase II was determined by a fluorescence competition assay using a Perkin-E...More data for this Ligand-Target Pair
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Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM11930(2-N-[(4-methoxyphenyl)methyl]thiophene-2,5-disulfo...)
Affinity DataKd:  0.490nMpH: 7.4 T: 2°CAssay Description:The binding of test compounds to purified human erythrocyte carbonic anhydrase II was determined by a fluorescence competition assay using a Perkin-E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM11931(2-N-(thiophen-2-ylmethyl)thiophene-2,5-disulfonami...)
Affinity DataKd:  0.830nMpH: 7.4 T: 2°CAssay Description:The binding of test compounds to purified human erythrocyte carbonic anhydrase II was determined by a fluorescence competition assay using a Perkin-E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM11932(4-hydroxy-1,1-dioxo-2-(thiophen-2-ylmethyl)-2H,3H,...)
Affinity DataKd:  0.200nMpH: 7.4 T: 2°CAssay Description:The binding of test compounds to purified human erythrocyte carbonic anhydrase II was determined by a fluorescence competition assay using a Perkin-E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM11933(4-hydroxy-2-(4-methoxyphenyl)-1,1-dioxo-2H,3H,4H-1...)
Affinity DataKd:  0.160nMpH: 7.4 T: 2°CAssay Description:The binding of test compounds to purified human erythrocyte carbonic anhydrase II was determined by a fluorescence competition assay using a Perkin-E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM11934((4R)-4-(ethylamino)-2-(2-methoxyethyl)-1,1-dioxo-2...)
Affinity DataKd:  0.320nMpH: 7.4 T: 2°CAssay Description:The binding of test compounds to purified human erythrocyte carbonic anhydrase II was determined by a fluorescence competition assay using a Perkin-E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM10885((4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-...)
Affinity DataKd:  0.130nMpH: 7.4 T: 2°CAssay Description:The binding of test compounds to purified human erythrocyte carbonic anhydrase II was determined by a fluorescence competition assay using a Perkin-E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM11935(2-(3-methoxyphenyl)-1,1-dioxo-2H,3H,4H-1,7,2-thien...)
Affinity DataKd:  0.100nMpH: 7.4 T: 2°CAssay Description:The binding of test compounds to purified human erythrocyte carbonic anhydrase II was determined by a fluorescence competition assay using a Perkin-E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM11936((4R)-2-(3-methoxyphenyl)-4-(methylamino)-1,1-dioxo...)
Affinity DataKd:  0.100nMpH: 7.4 T: 2°CAssay Description:The binding of test compounds to purified human erythrocyte carbonic anhydrase II was determined by a fluorescence competition assay using a Perkin-E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM11937((4S)-2-(3-methoxyphenyl)-4-(methylamino)-1,1-dioxo...)
Affinity DataKd:  1.70nMpH: 7.4 T: 2°CAssay Description:The binding of test compounds to purified human erythrocyte carbonic anhydrase II was determined by a fluorescence competition assay using a Perkin-E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pennsylvania

LigandPNGBDBM11938(2-(3-methoxyphenyl)-1,1-dioxo-2H-1,7,2-thieno[3,2-...)
Affinity DataKd:  0.130nMpH: 7.4 T: 2°CAssay Description:The binding of test compounds to purified human erythrocyte carbonic anhydrase II was determined by a fluorescence competition assay using a Perkin-E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed