Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50007711
TargetProthrombin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50066770((3R,6S,8aS)-5-Oxo-6-phenylmethanesulfonylamino-hex...)
Affinity DataKi:  111nMAssay Description:In vitro inhibition was measured against Human Thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50066766((3R,6R,8aS)-5-Oxo-6-phenylmethanesulfonylamino-hex...)
Affinity DataKi:  145nMAssay Description:In vitro inhibition was measured against Human Thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50066769((3R,6R,8aS)-6-(Naphthalene-1-sulfonylamino)-5-oxo-...)
Affinity DataKi:  751nMAssay Description:In vitro inhibition was measured against Human Thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50066768((3R,6S,8aS)-6-(Naphthalene-1-sulfonylamino)-5-oxo-...)
Affinity DataKi:  1.45E+3nMAssay Description:In vitro inhibition was measured against Human Thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50066769((3R,6R,8aS)-6-(Naphthalene-1-sulfonylamino)-5-oxo-...)
Affinity DataKi:  3.40E+3nMAssay Description:In vitro inhibition was measured against Human bovine pancreatic trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50066773((3R,6S,8aS)-6-Amino-5-oxo-hexahydro-thiazolo[3,2-a...)
Affinity DataKi:  3.58E+3nMAssay Description:In vitro inhibition was measured against Human bovine pancreatic trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50066771((3R,6S,8aS)-6-Amino-5-oxo-hexahydro-thiazolo[3,2-a...)
Affinity DataKi:  5.10E+3nMAssay Description:In vitro inhibition was measured against Human Thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50066766((3R,6R,8aS)-5-Oxo-6-phenylmethanesulfonylamino-hex...)
Affinity DataKi:  5.10E+3nMAssay Description:In vitro inhibition was measured against Human bovine pancreatic trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50066767((3R,6R,8aS)-6-Amino-5-oxo-hexahydro-thiazolo[3,2-a...)
Affinity DataKi:  5.36E+3nMAssay Description:In vitro inhibition was measured against Human bovine pancreatic trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50066769((3R,6R,8aS)-6-(Naphthalene-1-sulfonylamino)-5-oxo-...)
Affinity DataKi:  6.78E+3nMAssay Description:In vitro inhibition was measured against Human Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50066770((3R,6S,8aS)-5-Oxo-6-phenylmethanesulfonylamino-hex...)
Affinity DataKi:  7.90E+3nMAssay Description:In vitro inhibition was measured against Human bovine pancreatic trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50066772((3R,6R,8aS)-6-Amino-5-oxo-hexahydro-thiazolo[3,2-a...)
Affinity DataKi:  1.03E+4nMAssay Description:In vitro inhibition was measured against Human Thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50066771((3R,6S,8aS)-6-Amino-5-oxo-hexahydro-thiazolo[3,2-a...)
Affinity DataKi:  1.33E+4nMAssay Description:In vitro inhibition was measured against Human bovine pancreatic trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50066768((3R,6S,8aS)-6-(Naphthalene-1-sulfonylamino)-5-oxo-...)
Affinity DataKi:  1.78E+4nMAssay Description:In vitro inhibition was measured against Human Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50066773((3R,6S,8aS)-6-Amino-5-oxo-hexahydro-thiazolo[3,2-a...)
Affinity DataKi:  1.95E+4nMAssay Description:In vitro inhibition was measured against Human Thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50066768((3R,6S,8aS)-6-(Naphthalene-1-sulfonylamino)-5-oxo-...)
Affinity DataKi:  1.96E+4nMAssay Description:In vitro inhibition was measured against Bovine pancreatic trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50066772((3R,6R,8aS)-6-Amino-5-oxo-hexahydro-thiazolo[3,2-a...)
Affinity DataKi:  2.51E+4nMAssay Description:In vitro inhibition was measured against Human bovine pancreatic trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50066766((3R,6R,8aS)-5-Oxo-6-phenylmethanesulfonylamino-hex...)
Affinity DataKi:  2.60E+4nMAssay Description:In vitro inhibition was measured against Human Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50066771((3R,6S,8aS)-6-Amino-5-oxo-hexahydro-thiazolo[3,2-a...)
Affinity DataKi: >3.37E+4nMAssay Description:In vitro inhibition was measured against Human Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50066770((3R,6S,8aS)-5-Oxo-6-phenylmethanesulfonylamino-hex...)
Affinity DataKi: >3.37E+4nMAssay Description:In vitro inhibition was measured against Human Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50066767((3R,6R,8aS)-6-Amino-5-oxo-hexahydro-thiazolo[3,2-a...)
Affinity DataKi:  6.24E+4nMAssay Description:In vitro inhibition was measured against Human Thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed