Compile Data Set for Download or QSAR
Report error Found 49 Enz. Inhib. hit(s) with all data for entry = 50038801
TargetCyclin-dependent kinase 1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human cdc2/cyclin B assessed as [32P] incorporation in histone H1 from [gamma32P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM7478(CHEMBL23254 | 2-chloro-4-[(2-{[(2R)-1-hydroxy-3-me...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human cdk5/p35More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM7478(CHEMBL23254 | 2-chloro-4-[(2-{[(2R)-1-hydroxy-3-me...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human cdk2/cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM7478(CHEMBL23254 | 2-chloro-4-[(2-{[(2R)-1-hydroxy-3-me...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human cdc2/cyclin B assessed as [32P] incorporation in histone H1 from [gamma32P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM7478(CHEMBL23254 | 2-chloro-4-[(2-{[(2R)-1-hydroxy-3-me...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human cdk2/cyclin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50: 35nMAssay Description:Inhibition of human cdk2/cyclin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetCdc2(Starfish)
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50: 40nMAssay Description:Inhibition of starfish cdc2/cyclin B assessed as [32P] incorporation in histone H1 from 150 M [gamma32P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetCdc2(Starfish)
University of California

Curated by ChEMBL
LigandPNGBDBM7478(CHEMBL23254 | 2-chloro-4-[(2-{[(2R)-1-hydroxy-3-me...)
Affinity DataIC50: 50nMAssay Description:Inhibition of starfish cdc2/cyclin B assessed as [32P] incorporation in histone H1 from 150 M [gamma32P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human cdk2/cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50: 75nMAssay Description:Inhibition of human cdk5/p35More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Baker's yeast)
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50: 80nMAssay Description:Inhibition of Saccharomyces cerevisiae cdc28More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetCdc2(Starfish)
University of California

Curated by ChEMBL
LigandPNGBDBM7478(CHEMBL23254 | 2-chloro-4-[(2-{[(2R)-1-hydroxy-3-me...)
Affinity DataIC50: 250nMAssay Description:Inhibition of starfish cdc2/cyclin B assessed as [32P] incorporation in histone H1 from 1.5 mM [gamma32P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50113707(2,6,9-Trisubstitute purine, 2 | CHEMBL311228 | 2-[...)
Affinity DataIC50: 340nMAssay Description:Inhibition of human cdc2/cyclin B assessed as [32P] incorporation in histone H1 from [gamma32P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetCdc2(Starfish)
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50: 500nMAssay Description:Inhibition of starfish cdc2/cyclin B assessed as [32P] incorporation in histone H1 from 1.5 mM [gamma32P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50: 850nMAssay Description:Inhibition of human cdk4/cyclin D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Baker's yeast)
University of California

Curated by ChEMBL
LigandPNGBDBM7478(CHEMBL23254 | 2-chloro-4-[(2-{[(2R)-1-hydroxy-3-me...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of Saccharomyces cerevisiae cdc28More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetCyclin-dependent protein kinase PHO85(Baker's yeast)
University of California

Curated by ChEMBL
LigandPNGBDBM50113707(2,6,9-Trisubstitute purine, 2 | CHEMBL311228 | 2-[...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of yeast W303 Pho85 phosphorylation assessed as [32P] incorporation in histone H1 from [gamma32P]ATP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetInsulin receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM7478(CHEMBL23254 | 2-chloro-4-[(2-{[(2R)-1-hydroxy-3-me...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human insulin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM7478(CHEMBL23254 | 2-chloro-4-[(2-{[(2R)-1-hydroxy-3-me...)
Affinity DataIC50: 3.33E+3nMAssay Description:Inhibition of human Erk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetInsulin receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human insulin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Baker's yeast)
University of California

Curated by ChEMBL
LigandPNGBDBM50113707(2,6,9-Trisubstitute purine, 2 | CHEMBL311228 | 2-[...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of yeast W303 cdc28 phosphorylation assessed as [32P] incorporation in histone H1 from [gamma32P]ATP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human Erk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM7478(CHEMBL23254 | 2-chloro-4-[(2-{[(2R)-1-hydroxy-3-me...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human cdk4/cyclin D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetProtein kinase C gamma type(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PKCgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PKCbeta1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PKCalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PKCbeta2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM7478(CHEMBL23254 | 2-chloro-4-[(2-{[(2R)-1-hydroxy-3-me...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetProtein kinase C zeta type(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM7478(CHEMBL23254 | 2-chloro-4-[(2-{[(2R)-1-hydroxy-3-me...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PKCzetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM7478(CHEMBL23254 | 2-chloro-4-[(2-{[(2R)-1-hydroxy-3-me...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PKCepsilonMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM7478(CHEMBL23254 | 2-chloro-4-[(2-{[(2R)-1-hydroxy-3-me...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PKCdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetProtein kinase C gamma type(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM7478(CHEMBL23254 | 2-chloro-4-[(2-{[(2R)-1-hydroxy-3-me...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PKCgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM7478(CHEMBL23254 | 2-chloro-4-[(2-{[(2R)-1-hydroxy-3-me...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PKCbeta1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM7478(CHEMBL23254 | 2-chloro-4-[(2-{[(2R)-1-hydroxy-3-me...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PKCbeta2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetProtein kinase C zeta type(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PKCzetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetProtein kinase C eta type(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM7478(CHEMBL23254 | 2-chloro-4-[(2-{[(2R)-1-hydroxy-3-me...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PKCetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetProtein kinase C eta type(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PKCetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM7478(CHEMBL23254 | 2-chloro-4-[(2-{[(2R)-1-hydroxy-3-me...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PKCalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PKCepsilonMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PKCdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetMeiotic mRNA stability protein kinase SSN3(Baker's yeast)
University of California

Curated by ChEMBL
LigandPNGBDBM50113707(2,6,9-Trisubstitute purine, 2 | CHEMBL311228 | 2-[...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of yeast W303 Srb10 phosphorylation assessed as [32P] incorporation in histone H1 from [gamma32P]ATP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase KIN28(Baker's yeast)
University of California

Curated by ChEMBL
LigandPNGBDBM50113707(2,6,9-Trisubstitute purine, 2 | CHEMBL311228 | 2-[...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of yeast W303 Kin28 phosphorylation assessed as [32P] incorporation in histone H1 from [gamma32P]ATP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase CAK1(Baker's yeast)
University of California

Curated by ChEMBL
LigandPNGBDBM50267719(2-(6-((3-chlorophenyl)(methyl)amino)-9-isopropyl-9...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of yeast W303 Cak1 phosphorylation assessed as [32P] incorporation in histone H1 from [gamma32P]ATP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetMeiotic mRNA stability protein kinase SSN3(Baker's yeast)
University of California

Curated by ChEMBL
LigandPNGBDBM50267719(2-(6-((3-chlorophenyl)(methyl)amino)-9-isopropyl-9...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of yeast W303 Srb10 phosphorylation assessed as [32P] incorporation in histone H1 from [gamma32P]ATP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase KIN28(Baker's yeast)
University of California

Curated by ChEMBL
LigandPNGBDBM50267719(2-(6-((3-chlorophenyl)(methyl)amino)-9-isopropyl-9...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of yeast W303 Kin28 phosphorylation assessed as [32P] incorporation in histone H1 from [gamma32P]ATP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetCyclin-dependent protein kinase PHO85(Baker's yeast)
University of California

Curated by ChEMBL
LigandPNGBDBM50267719(2-(6-((3-chlorophenyl)(methyl)amino)-9-isopropyl-9...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of yeast W303 Pho85 phosphorylation assessed as [32P] incorporation in histone H1 from [gamma32P]ATP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Baker's yeast)
University of California

Curated by ChEMBL
LigandPNGBDBM50267719(2-(6-((3-chlorophenyl)(methyl)amino)-9-isopropyl-9...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of yeast W303 cdc28 phosphorylation assessed as [32P] incorporation in histone H1 from [gamma32P]ATP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase CAK1(Baker's yeast)
University of California

Curated by ChEMBL
LigandPNGBDBM50113707(2,6,9-Trisubstitute purine, 2 | CHEMBL311228 | 2-[...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of yeast W303 Cak1 phosphorylation assessed as [32P] incorporation in histone H1 from [gamma32P]ATP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed