Compile Data Set for Download or QSAR
Report error Found 268 Enz. Inhib. hit(s) with all data for entry = 50007607
LigandPNGBDBM50065308((Z )-3-[(2,4-dimethyl-3-(ethoxycarbonyl)pyrrol-5-y...)
Affinity DataIC50: 70nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50065303(3-[1-(3-Ethyl-4,5-dimethyl-1H-pyrrol-2-yl)-meth-(Z...)
Affinity DataIC50: 140nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50065283(4-Methyl-5-[2-oxo-1,2-dihydro-indol-(3Z)-ylideneme...)
Affinity DataIC50: 180nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50065292(3-[1-(3,5-Dimethyl-1H-pyrrol-2-yl)-meth-(Z)-yliden...)
Affinity DataIC50: 300nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM17015(CHEMBL86755 | Indolinone based inhibitor, 1 | (3Z)...)
Affinity DataIC50: 390nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM4882(3-(4-methyl-2-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-...)
Affinity DataIC50: 400nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM17747(CHEMBL328710 | (3Z)-3-{[4-(dimethylamino)phenyl]me...)
Affinity DataIC50: 800nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50065288(3-[1-(3,5-Dimethyl-1H-pyrrol-2-yl)-meth-(Z)-yliden...)
Affinity DataIC50: 1.00E+3nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM4810(cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...)
Affinity DataIC50: 1.04E+3nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50065306(SU-4984 | 3-[4-(1-formylpiperazin-4-yl)benzylideny...)
Affinity DataIC50: 1.60E+3nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50065312((Z)-4-methyl-3-(4-morpholinobenzylidene)indolin-2-...)
Affinity DataIC50: 2.10E+3nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50065273(3-[1-(5-Methylsulfanyl-thiophen-2-yl)-meth-(Z)-yli...)
Affinity DataIC50: 2.34E+3nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50065290((Z)-4-(4-((4-methyl-2-oxoindolin-3-ylidene)methyl)...)
Affinity DataIC50: 2.50E+3nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50065280(3-[1-(4-Morpholin-4-yl-phenyl)-meth-(Z)-ylidene]-1...)
Affinity DataIC50: 2.50E+3nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50065304(3-[1-(4-Hydroxy-phenyl)-meth-(Z)-ylidene]-1,3-dihy...)
Affinity DataIC50: 2.70E+3nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50065311(3-[1-(3,4-Dimethyl-1H-pyrrol-2-yl)-meth-(Z)-yliden...)
Affinity DataIC50: 2.70E+3nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50065302(6-Fluoro-3-[1-(1H-pyrrol-2-yl)-meth-(Z)-ylidene]-1...)
Affinity DataIC50: 2.80E+3nMAssay Description:Test concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Platelet-derived growth factor receptor beta (PDGF RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50065314(3-[1-(4-Pyrrolidin-1-yl-phenyl)-meth-(Z)-ylidene]-...)
Affinity DataIC50: 3.00E+3nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50065317(5-Chloro-3-[1-(1H-pyrrol-2-yl)-meth-(Z)-ylidene]-1...)
Affinity DataIC50: 3.00E+3nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50065294(3-(4-Dimethylamino-benzylidene)-4-methyl-1,3-dihyd...)
Affinity DataIC50: 3.00E+3nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50065295(3-[1-(5-Ethyl-thiophen-2-yl)-meth-(Z)-ylidene]-1,3...)
Affinity DataIC50: 3.40E+3nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50065277(5-Chloro-3-[1-(4-morpholin-4-yl-phenyl)-meth-(Z)-y...)
Affinity DataIC50: 4.10E+3nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50065307(5-Chloro-3-(4-hydroxy-3,5-diisopropyl-benzylidene)...)
Affinity DataIC50: 4.30E+3nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50065276(3-[1-(4-Piperidin-1-yl-phenyl)-meth-(Z)-ylidene]-1...)
Affinity DataIC50: 4.50E+3nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50065298(3-[1-(4-Dimethylamino-phenyl)-meth-(Z)-ylidene]-6-...)
Affinity DataIC50: 4.60E+3nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50065306(SU-4984 | 3-[4-(1-formylpiperazin-4-yl)benzylideny...)
Affinity DataIC50: 5.10E+3nMAssay Description:Test concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Platelet-derived growth factor receptor beta (PDGF RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50065297(3-[1-(4-Isopropyl-phenyl)-meth-(E)-ylidene]-1,3-di...)
Affinity DataIC50: 5.20E+3nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50065289(3-{4-Methyl-5-[2-oxo-1,2-dihydro-indol-(3Z)-yliden...)
Affinity DataIC50: 6.30E+3nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50065271(3-[1-(4-Hydroxy-3,5-diisopropyl-phenyl)-meth-(Z)-y...)
Affinity DataIC50: 7.00E+3nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Her-2 receptor tyrosine kinase (HER-2 RTK)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50065284(CHEMBL321781 | 3-[1-(4-Chloro-1H-pyrazol-3-yl)-met...)
Affinity DataIC50: 7.41E+3nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50065296(3-[1-(4-Methoxy-phenyl)-meth-(Z)-ylidene]-1,3-dihy...)
Affinity DataIC50: 7.60E+3nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Sugen

Curated by ChEMBL
LigandPNGBDBM50065275(3-(3,5-di-tert-butyl-4-hydroxybenzylidene)indolin-...)
Affinity DataIC50: 7.90E+3nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Epidermal growth factor receptor (EGF RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50065307(5-Chloro-3-(4-hydroxy-3,5-diisopropyl-benzylidene)...)
Affinity DataIC50: 8.20E+3nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Her-2 receptor tyrosine kinase (HER-2 RTK)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50065304(3-[1-(4-Hydroxy-phenyl)-meth-(Z)-ylidene]-1,3-dihy...)
Affinity DataIC50: 8.39E+3nMAssay Description:Test concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Platelet-derived growth factor receptor beta (PDGF RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50065275(3-(3,5-di-tert-butyl-4-hydroxybenzylidene)indolin-...)
Affinity DataIC50: 8.40E+3nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50065271(3-[1-(4-Hydroxy-3,5-diisopropyl-phenyl)-meth-(Z)-y...)
Affinity DataIC50: 8.50E+3nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Sugen

Curated by ChEMBL
LigandPNGBDBM50065307(5-Chloro-3-(4-hydroxy-3,5-diisopropyl-benzylidene)...)
Affinity DataIC50: 9.50E+3nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Epidermal growth factor receptor (EGF RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50065277(5-Chloro-3-[1-(4-morpholin-4-yl-phenyl)-meth-(Z)-y...)
Affinity DataIC50: 1.00E+4nMAssay Description:Test concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Platelet-derived growth factor receptor beta (PDGF RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50065277(5-Chloro-3-[1-(4-morpholin-4-yl-phenyl)-meth-(Z)-y...)
Affinity DataIC50: 1.00E+4nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Her-2 receptor tyrosine kinase (HER-2 RTK)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Sugen

Curated by ChEMBL
LigandPNGBDBM50065297(3-[1-(4-Isopropyl-phenyl)-meth-(E)-ylidene]-1,3-di...)
Affinity DataIC50: 1.00E+4nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Insulin-like growth factor I receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Sugen

Curated by ChEMBL
LigandPNGBDBM50065310(5-Bromo-3-[1-(4-morpholin-4-yl-phenyl)-meth-(Z)-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Epidermal growth factor receptor (EGF RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50065310(5-Bromo-3-[1-(4-morpholin-4-yl-phenyl)-meth-(Z)-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Sugen

Curated by ChEMBL
LigandPNGBDBM50065277(5-Chloro-3-[1-(4-morpholin-4-yl-phenyl)-meth-(Z)-y...)
Affinity DataIC50: 1.00E+4nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Epidermal growth factor receptor (EGF RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Sugen

Curated by ChEMBL
LigandPNGBDBM50065277(5-Chloro-3-[1-(4-morpholin-4-yl-phenyl)-meth-(Z)-y...)
Affinity DataIC50: 1.00E+4nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Insulin-like growth factor I receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50065310(5-Bromo-3-[1-(4-morpholin-4-yl-phenyl)-meth-(Z)-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Test concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Platelet-derived growth factor receptor beta (PDGF RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Sugen

Curated by ChEMBL
LigandPNGBDBM50065310(5-Bromo-3-[1-(4-morpholin-4-yl-phenyl)-meth-(Z)-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Insulin-like growth factor I receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50065310(5-Bromo-3-[1-(4-morpholin-4-yl-phenyl)-meth-(Z)-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Her-2 receptor tyrosine kinase (HER-2 RTK)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Sugen

Curated by ChEMBL
LigandPNGBDBM50065271(3-[1-(4-Hydroxy-3,5-diisopropyl-phenyl)-meth-(Z)-y...)
Affinity DataIC50: 1.01E+4nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Insulin-like growth factor I receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM17015(CHEMBL86755 | Indolinone based inhibitor, 1 | (3Z)...)
Affinity DataIC50: 1.20E+4nMAssay Description:Test concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Platelet-derived growth factor receptor beta (PDGF RTK).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50065318(3-[1-(3-tert-Butyl-4-methoxy-phenyl)-meth-(Z)-ylid...)
Affinity DataIC50: 1.32E+4nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Her-2 receptor tyrosine kinase (HER-2 RTK)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Displayed 1 to 50 (of 268 total ) | Next | Last >>
Jump to: