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Found
119
Enz. Inhib. hit(s) with all data for entry = 5147
Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50008782
(CHEMBL44237 | EPIDEPRIDE | Epidepride;N-(1-Ethyl-p...)
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Ki: 0.0100nM
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Date in BDB:
3/3/2012
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM81492
(CAS_2062-84-2 | NSC_16363 | BENPERIDOL)
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Ki: 0.0270nM
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Date in BDB:
3/3/2012
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50008735
(CHEMBL8514 | BUTACLAMOL,d- | (+)-3-(tert-butyl)-(3...)
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Ki: 0.0500nM
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Date in BDB:
3/3/2012
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM81492
(CAS_2062-84-2 | NSC_16363 | BENPERIDOL)
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Ki: 0.0660nM
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM85223
(NSC_115368 | CAS_115368 | Perospirone)
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Ki: 0.0900nM
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Date in BDB:
3/3/2012
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Target
D(3) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM78433
(2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...)
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Ki: 0.110nM
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Date in BDB:
3/3/2012
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Target
5-hydroxytryptamine receptor 2A
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50034043
(CHEMBL14376 | 1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazo...)
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Ki: 0.120nM
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM78576
(MLS000028463 | cid_941651 | SMR000058396 | CIS-THI...)
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Ki: 0.120nM
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Target
D(3) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50130273
(4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...)
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Ki: 0.130nM
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Target
5-hydroxytryptamine receptor 2A
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50095027
((2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-eth...)
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Ki: 0.140nM
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Date in BDB:
3/3/2012
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50130273
(4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...)
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Ki: 0.160nM
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Target
5-hydroxytryptamine receptor 2A
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001885
(3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
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Ki: 0.210nM
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50017705
(1-(1-(4-(4-fluorophenyl)-4-oxobutyl)-1,2,3,6-tetra...)
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Ki: 0.25nM
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Date in BDB:
3/3/2012
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001885
(3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
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Ki: 0.25nM
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3/3/2012
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Target
5-hydroxytryptamine receptor 2A
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001786
(1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...)
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Ki: 0.300nM
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3/3/2012
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001885
(3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
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Ki: 0.300nM
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Date in BDB:
3/3/2012
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Target
D(3) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50026957
((cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-yli...)
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Ki: 0.300nM
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM85222
(Lurasidone | CAS_441351-20-8 | SM 13496)
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Ki: 0.300nM
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM21398
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
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Ki: 0.350nM
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Date in BDB:
3/3/2012
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50034043
(CHEMBL14376 | 1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazo...)
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Ki: 0.350nM
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM81493
(CAS_749-13-3 | TRIFLUORPERIDOL)
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Ki: 0.350nM
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Date in BDB:
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50002338
(10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...)
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Ki: 0.400nM
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Target
D(3) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM79181
(cid_2913535 | TRIFLUOPERAZINE | SMR000059133 | MLS...)
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Ki: 0.450nM
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Target
5-hydroxytryptamine receptor 2A
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001775
(cid_5074 | Ritanserine | 6-(2-{4-[Bis-(4-fluoro-ph...)
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Ki: 0.540nM
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Date in BDB:
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM85223
(NSC_115368 | CAS_115368 | Perospirone)
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Ki: 0.600nM
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Date in BDB:
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50334150
(1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)...)
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Ki: 0.600nM
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Date in BDB:
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50005118
(3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-h...)
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Ki: 0.640nM
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Date in BDB:
3/3/2012
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50130257
(CHEMBL90125 | (E)-chlorprothixene | CHLORPROTHIXEN...)
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Ki: 0.640nM
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PubMed
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001888
([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...)
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Ki: 0.660nM
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM85048
(CHEMBL537481 | Glaxo 1192U90)
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Ki: 0.800nM
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50048803
(5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-et...)
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Ki: 0.800nM
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Date in BDB:
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PubMed
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Target
D(3) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001888
([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...)
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Ki: 0.840nM
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Date in BDB:
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50017705
(1-(1-(4-(4-fluorophenyl)-4-oxobutyl)-1,2,3,6-tetra...)
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Ki: 0.840nM
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM21398
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
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Ki: 0.840nM
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Date in BDB:
3/3/2012
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PubMed
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM79181
(cid_2913535 | TRIFLUOPERAZINE | SMR000059133 | MLS...)
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Ki: 0.960nM
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Date in BDB:
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001786
(1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...)
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Ki: 1nM
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Date in BDB:
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Target
5-hydroxytryptamine receptor 2A
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50002338
(10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...)
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Ki: 1.10nM
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Date in BDB:
3/3/2012
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PubMed
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Target
D(3) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50048803
(5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-et...)
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Ki: 1.10nM
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Date in BDB:
3/3/2012
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Target
D(2) dopamine receptor
(Human)
University of Toronto
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Ligand
BDBM78434
(2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phen...)
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Ki: 1.20nM
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Date in BDB:
3/3/2012
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PubMed
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
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Ligand
BDBM85222
(Lurasidone | CAS_441351-20-8 | SM 13496)
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Ki: 1.20nM
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Date in BDB:
3/3/2012
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PubMed
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
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Ligand
BDBM50048803
(5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-et...)
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Ki: 1.20nM
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Date in BDB:
3/3/2012
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PubMed
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001888
([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...)
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Ki: 1.20nM
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Date in BDB:
3/3/2012
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Target
5-hydroxytryptamine receptor 2A
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM85223
(NSC_115368 | CAS_115368 | Perospirone)
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Ki: 1.30nM
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Date in BDB:
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Target
D(3) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
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Ligand
BDBM50002338
(10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...)
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Ki: 1.5nM
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
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Ligand
BDBM50002338
(10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...)
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Ki: 1.5nM
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
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Ligand
BDBM22869
(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
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Ki: 1.60nM
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Date in BDB:
3/3/2012
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
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Ligand
BDBM50026957
((cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-yli...)
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Ki: 1.60nM
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Date in BDB:
3/3/2012
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
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Ligand
BDBM82479
(CAS_132539-06-1 | NSC_4585 | OLANZAPINE | USRE4934...)
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Ki: 1.60nM
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ChEBI
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In Depth
Date in BDB:
3/3/2012
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PubMed
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Target
5-hydroxytryptamine receptor 2A
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001888
([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...)
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Ki: 1.80nM
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Date in BDB:
3/3/2012
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PubMed
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Target
5-hydroxytryptamine receptor 2A
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50010594
(ISOCLOZAPINE | 2-Chloro-11-(4-methyl-piperazin-1-y...)
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Ki: 1.80nM
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