Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50036608
TargetMetabotropic glutamate receptor 5(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064248((1S,2S,4S,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  720nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM26431((2R)-2-aminopentanedioic acid | D-Glu | D-Glutamat...)
Affinity DataEC50:  290nMAssay Description:Compound was tested for the inhibition of metabotropic glutamate receptor 2 (mGluR2).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50004863(1S, 3R-ACPD | CHEMBL29726 | 1R,3R-ACPD | 1R,3S-ACP...)
Affinity DataEC50:  5.00E+4nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM26431((2R)-2-aminopentanedioic acid | D-Glu | D-Glutamat...)
Affinity DataEC50:  4.90E+3nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064247((1S,2S,4S,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064248((1S,2S,4S,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  5.30E+3nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM66976(SMR001230688 | trans-( )-ACPD monohydrate | cid_16...)
Affinity DataEC50:  8.20E+4nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064245((1R,2S,4R,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM66976(SMR001230688 | trans-( )-ACPD monohydrate | cid_16...)
Affinity DataEC50:  1.50E+4nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064247((1S,2S,4S,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  9.10E+4nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064245((1R,2S,4R,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM26431((2R)-2-aminopentanedioic acid | D-Glu | D-Glutamat...)
Affinity DataEC50:  9.80E+3nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064246((1R,2S,4R,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  1.21E+5nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064248((1S,2S,4S,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  2.30E+4nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50056272((2S,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dicarboxy...)
Affinity DataEC50:  5.10nMAssay Description:Agonistic activity against Human Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 5(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064246((1R,2S,4R,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  5.70E+4nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064245((1R,2S,4R,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064245((1R,2S,4R,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50: >3.00E+5nMAssay Description:Compound was tested for the inhibition of metabotropic glutamate receptor 2 (mGluR2).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM66976(SMR001230688 | trans-( )-ACPD monohydrate | cid_16...)
Affinity DataEC50:  2.30E+4nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064247((1S,2S,4S,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  2.32E+5nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM66976(SMR001230688 | trans-( )-ACPD monohydrate | cid_16...)
Affinity DataEC50:  2.00E+3nMAssay Description:Compound was tested for the inhibition of metabotropic glutamate receptor 2 (mGluR2).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064245((1R,2S,4R,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50004863(1S, 3R-ACPD | CHEMBL29726 | 1R,3R-ACPD | 1R,3S-ACP...)
Affinity DataEC50:  3.00E+4nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 3 (mGluR3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064246((1R,2S,4R,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  1.00E+6nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50004051(CHEMBL285843 | 2-Amino-4-phosphono-butyric acid | ...)
Affinity DataEC50:  280nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50004863(1S, 3R-ACPD | CHEMBL29726 | 1R,3R-ACPD | 1R,3S-ACP...)
Affinity DataEC50: >3.00E+5nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064247((1S,2S,4S,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  3.80E+4nMAssay Description:Compound was tested for the inhibition of metabotropic glutamate receptor 2 (mGluR2).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM26431((2R)-2-aminopentanedioic acid | D-Glu | D-Glutamat...)
Affinity DataEC50:  4.90E+3nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50004863(1S, 3R-ACPD | CHEMBL29726 | 1R,3R-ACPD | 1R,3S-ACP...)
Affinity DataEC50:  1.30E+4nMAssay Description:Compound was tested for the inhibition of metabotropic glutamate receptor 2 (mGluR2).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064246((1R,2S,4R,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  8.00E+5nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM26431((2R)-2-aminopentanedioic acid | D-Glu | D-Glutamat...)
Affinity DataEC50:  3.10E+3nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064248((1S,2S,4S,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  330nMAssay Description:Compound was tested for the inhibition of metabotropic glutamate receptor 2 (mGluR2).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064246((1R,2S,4R,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  5.40E+4nMAssay Description:Compound was tested for the inhibition of metabotropic glutamate receptor 2 (mGluR2).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50004051(CHEMBL285843 | 2-Amino-4-phosphono-butyric acid | ...)
Affinity DataEC50:  330nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50056272((2S,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dicarboxy...)
Affinity DataEC50:  24nMAssay Description:Agonistic activity against Human Metabotropic glutamate receptor 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 5(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50004863(1S, 3R-ACPD | CHEMBL29726 | 1R,3R-ACPD | 1R,3S-ACP...)
Affinity DataEC50: >3.00E+5nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064247((1S,2S,4S,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM66976(SMR001230688 | trans-( )-ACPD monohydrate | cid_16...)
Affinity DataEC50:  8.00E+5nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064248((1S,2S,4S,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  1.60E+3nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed