Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 2257
TargetAndrogen receptor(Rat)
University of Tennessee At Memphis

LigandPNGBDBM18161(DHT | Dihydrotestosterone | [3H]DHT | (5alpha,17be...)
Affinity DataKi:  0.280nM ΔG°:  -50.7kJ/mole EC50:  1nMpH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Rat)
University of Tennessee At Memphis

LigandPNGBDBM18699((2R)-3-bromo-2-hydroxy-2-methyl-N-[4-nitro-3-(trif...)
Affinity DataKi:  0.300nM ΔG°:  -50.5kJ/mole EC50:  500nMpH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
University of Tennessee At Memphis

LigandPNGBDBM18701((2R)-2-hydroxy-3-iodo-2-methyl-N-[4-nitro-3-(trifl...)
Affinity DataKi:  0.860nM ΔG°:  -48.1kJ/mole EC50:  500nMpH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
University of Tennessee At Memphis

LigandPNGBDBM18685(CHEMBL333745 | (2R)-3-{[4-(2-chloroacetamido)pheny...)
Affinity DataKi:  1.65nM ΔG°:  -46.6kJ/mole EC50:  100nMpH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
University of Tennessee At Memphis

LigandPNGBDBM18700((2R)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydro...)
Affinity DataKi:  2.79nM ΔG°:  -45.4kJ/mole EC50:  500nMpH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
University of Tennessee At Memphis

LigandPNGBDBM18698((2R)-3-bromo-N-[4-cyano-3-(trifluoromethyl)phenyl]...)
Affinity DataKi:  7.98nM ΔG°:  -43.0kJ/mole EC50:  500nMpH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
University of Tennessee At Memphis

LigandPNGBDBM18678(CHEMBL63560 | (2R)-N-[4-cyano-3-(trifluoromethyl)p...)
Affinity DataKi:  11nM ΔG°:  -42.2kJ/mole EC50:  1.00E+3nMpH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed