Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50007353
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061469(1-[4-(8-CHLORO-3-METHYL-5,6-DIHYDRO-BENZO[5,6]CYCL...)
Affinity DataIC50: 40nMAssay Description:Compound was tested for the inhibition of FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061819(1-[4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclo...)
Affinity DataIC50: 60nMAssay Description:Compound was tested for the inhibition of FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061811(1-[4-(8-Chloro-3-iodo-5,6-dihydro-benzo[5,6]cycloh...)
Affinity DataIC50: 68nMAssay Description:Compound was tested for the inhibition of FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061818(1-[4-(3,8-Dichloro-5,6-dihydro-benzo[5,6]cyclohept...)
Affinity DataIC50: 72nMAssay Description:Compound was tested for the inhibition of FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM14455(4-[2-(4-{6-bromo-13-chloro-4-azatricyclo[9.4.0.0^{...)
Affinity DataIC50: 90nMAssay Description:Inhibition of FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061814(1-[4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclo...)
Affinity DataIC50: 160nMAssay Description:Compound was tested for the inhibition of FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM14454(1-(4-{13-chloro-4-azatricyclo[9.4.0.0^{3,8}]pentad...)
Affinity DataIC50: 250nMAssay Description:Compound was tested for the inhibition of FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061820(1-[4-(8-Chloro-3-methylsulfanyl-5,6-dihydro-benzo[...)
Affinity DataIC50: 420nMAssay Description:Compound was tested for the inhibition of FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061825(1-[4-(8-Chloro-3-trifluoromethyl-5,6-dihydro-benzo...)
Affinity DataIC50: 430nMAssay Description:Compound was tested for the inhibition of FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061489(1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,...)
Affinity DataIC50: 470nMAssay Description:Compound was tested for the inhibition of FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061826(1-[4-(8-Chloro-3-methoxy-5,6-dihydro-benzo[5,6]cyc...)
Affinity DataIC50: 490nMAssay Description:Compound was tested for the inhibition of FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061458(1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,...)
Affinity DataIC50: 530nMAssay Description:Compound was tested for the inhibition of FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061823(1-[4-(8-Chloro-3-methyl-5,6-dihydro-benzo[5,6]cycl...)
Affinity DataIC50: 550nMAssay Description:Compound was tested for the inhibition of FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061824(1-[4-(8-Chloro-3-nitro-5,6-dihydro-benzo[5,6]cyclo...)
Affinity DataIC50: 570nMAssay Description:Compound was tested for the inhibition of FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061809(1-[4-(3,8-Dichloro-5,6-dihydro-benzo[5,6]cyclohept...)
Affinity DataIC50: 580nMAssay Description:Compound was tested for the inhibition of FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061812(1-[4-(8-Chloro-3-hydroxy-5,6-dihydro-benzo[5,6]cyc...)
Affinity DataIC50: 640nMAssay Description:Compound was tested for the inhibition of FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061821(1-[4-(8-Chloro-3-fluoro-5,6-dihydro-benzo[5,6]cycl...)
Affinity DataIC50: 650nMAssay Description:Compound was tested for the inhibition of FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061816(1-[4-(8-Chloro-3-thiocyanato-5,6-dihydro-benzo[5,6...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was tested for the inhibition of FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061810(1-[4-(3-Amino-8-chloro-5,6-dihydro-benzo[5,6]cyclo...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was tested for the inhibition of FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061822(1-[4-(8-Chloro-3-ethylamino-5,6-dihydro-benzo[5,6]...)
Affinity DataIC50: 1.30E+3nMAssay Description:Compound was tested for the inhibition of FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061815(8-Chloro-11-[1-(2-pyridin-4-yl-acetyl)-piperidin-4...)
Affinity DataIC50: 1.40E+3nMAssay Description:Compound was tested for the inhibition of FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061813(1-[4-(8-Chloro-3-fluoro-5,6-dihydro-benzo[5,6]cycl...)
Affinity DataIC50: 3.80E+3nMAssay Description:Compound was tested for the inhibition of FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061817(1-[4-(3-tert-Butyl-8-chloro-5,6-dihydro-benzo[5,6]...)
Affinity DataIC50: 4.00E+3nMAssay Description:Compound was tested for the inhibition of FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061827(N-{8-Chloro-11-[1-(2-pyridin-4-yl-acetyl)-piperidi...)
Affinity DataIC50: 4.60E+3nMAssay Description:Compound was tested for the inhibition of FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50061811(1-[4-(8-Chloro-3-iodo-5,6-dihydro-benzo[5,6]cycloh...)
Affinity DataIC50: 3.60E+4nMAssay Description:Compound was tested for the inhibition of Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50061469(1-[4-(8-CHLORO-3-METHYL-5,6-DIHYDRO-BENZO[5,6]CYCL...)
Affinity DataIC50: 4.00E+4nMAssay Description:Compound was tested for the inhibition of Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50061819(1-[4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclo...)
Affinity DataIC50: 4.00E+4nMAssay Description:Compound was tested for the inhibition of Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50061814(1-[4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclo...)
Affinity DataIC50: 4.00E+4nMAssay Description:Compound was tested for the inhibition of Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50061818(1-[4-(3,8-Dichloro-5,6-dihydro-benzo[5,6]cyclohept...)
Affinity DataIC50: 4.20E+4nMAssay Description:Compound was tested for the inhibition of Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50061823(1-[4-(8-Chloro-3-methyl-5,6-dihydro-benzo[5,6]cycl...)
Affinity DataIC50: 4.30E+4nMAssay Description:Compound was tested for the inhibition of Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50061489(1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,...)
Affinity DataIC50: 4.60E+4nMAssay Description:Compound was tested for the inhibition of Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM14454(1-(4-{13-chloro-4-azatricyclo[9.4.0.0^{3,8}]pentad...)
Affinity DataIC50: 1.14E+5nMAssay Description:Compound was tested for the inhibition of Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed