Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50036555
TargetDelta-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50061061((4aR,8aS)-6-Ethyl-8a-(3-hydroxy-phenyl)-3-methyl-4...)
Affinity DataIC50: 34nMAssay Description:In vitro agonist activity for Opioid receptor delta 1 was determined in a mouse vas deferens assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50061061((4aR,8aS)-6-Ethyl-8a-(3-hydroxy-phenyl)-3-methyl-4...)
Affinity DataIC50: 330nMAssay Description:In vitro antagonist activity against Opioid receptor delta 1 in the presence of 30 nM naltrindole, in a mouse vas deferens assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50061061((4aR,8aS)-6-Ethyl-8a-(3-hydroxy-phenyl)-3-methyl-4...)
Affinity DataIC50: 462nMAssay Description:Inv itro antagonist activity against Opioid receptor delta 1 in the presence of 30 nM naltrindole, in a mouse vas deferens assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50039029(CHEMBL13470 | 3-[(4-Allyl-2,5-dimethyl-piperazin-1...)
Affinity DataIC50: 634nMAssay Description:In vitro antagonist activity against Opioid receptor delta 1 in the presence of 30 nM naltrindole, in a mouse vas deferens assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50039029(CHEMBL13470 | 3-[(4-Allyl-2,5-dimethyl-piperazin-1...)
Affinity DataIC50: 634nMAssay Description:In vitro antagonist activity against Opioid receptor delta 1 in the presence of 30 nM naltrindole, in a mouse vas deferens assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM21864(NALTRINDOLE | (8R)-7-(cyclopropylmethyl)-5,6,7,8,1...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity against Opioid receptor delta 1 using [3H][D-Ala2, D-Leu5]-enkephalin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50218796(CHEMBL557978 | oxymorphindole | OXYMORPHINDOLE CHL...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity against Opioid receptor delta 1 using [3H][D-Ala2, D-Leu5]-enkephalin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50061064((4aR,8aS)-6-Cyclopropylmethyl-8a-(3-hydroxy-phenyl...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity against Opioid receptor delta 1 using [3H][D-Ala2, D-Leu5]-enkephalin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50039029(CHEMBL13470 | 3-[(4-Allyl-2,5-dimethyl-piperazin-1...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity against Opioid receptor delta 1 using [3H][D-Ala2, D-Leu5]-enkephalin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50061063((4aR,8aS)-8a-(3-Hydroxy-phenyl)-3,6-dimethyl-4,4a,...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity against Opioid receptor delta 1 using [3H][D-Ala2, D-Leu5]-enkephalin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50061062(3-((4aS,11aR)-2-Ethyl-1,2,3,4,5,6,11,11a-octahydro...)
Affinity DataKi:  7.10nMAssay Description:Binding affinity against Opioid receptor delta 1 using [3H][D-Ala2, D-Leu5]-enkephalin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50061062(3-((4aS,11aR)-2-Ethyl-1,2,3,4,5,6,11,11a-octahydro...)
Affinity DataKi:  7.10nMAssay Description:Binding affinity against Opioid receptor delta 1 using [3H][D-Ala2, D-Leu5]-enkephalin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM21864(NALTRINDOLE | (8R)-7-(cyclopropylmethyl)-5,6,7,8,1...)
Affinity DataKi:  9.5nMAssay Description:Binding affinity against Opioid receptor kappa 1 using [3H]-U-69,593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50061064((4aR,8aS)-6-Cyclopropylmethyl-8a-(3-hydroxy-phenyl...)
Affinity DataKi:  14nMAssay Description:Binding affinity against Opioid receptor mu 1 using [3H][D-Ala2, MePhe4, Gly-ol5]-enkephalin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM21864(NALTRINDOLE | (8R)-7-(cyclopropylmethyl)-5,6,7,8,1...)
Affinity DataKi:  15nMAssay Description:Binding affinity against Opioid receptor mu 1 using [3H][D-Ala2, MePhe4, Gly-ol5]-enkephalin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50061064((4aR,8aS)-6-Cyclopropylmethyl-8a-(3-hydroxy-phenyl...)
Affinity DataKi:  63nMAssay Description:Binding affinity against Opioid receptor kappa 1 using [3H]-U-69,593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50218796(CHEMBL557978 | oxymorphindole | OXYMORPHINDOLE CHL...)
Affinity DataKi:  77nMAssay Description:Binding affinity against Opioid receptor kappa 1 using [3H]-U-69,593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50061063((4aR,8aS)-8a-(3-Hydroxy-phenyl)-3,6-dimethyl-4,4a,...)
Affinity DataKi:  93nMAssay Description:Binding affinity against Opioid receptor mu 1 using [3H][D-Ala2, MePhe4, Gly-ol5]-enkephalin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50061062(3-((4aS,11aR)-2-Ethyl-1,2,3,4,5,6,11,11a-octahydro...)
Affinity DataKi:  167nMAssay Description:Binding affinity against Opioid receptor kappa 1 using [3H]-U-69,593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50061062(3-((4aS,11aR)-2-Ethyl-1,2,3,4,5,6,11,11a-octahydro...)
Affinity DataKi:  334nMAssay Description:Binding affinity against Opioid receptor kappa 1 using [3H]-U-69,593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50061061((4aR,8aS)-6-Ethyl-8a-(3-hydroxy-phenyl)-3-methyl-4...)
Affinity DataKi:  407nMAssay Description:Binding affinity against Opioid receptor mu 1 using [3H][D-Ala2, MePhe4, Gly-ol5]-enkephalin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50061063((4aR,8aS)-8a-(3-Hydroxy-phenyl)-3,6-dimethyl-4,4a,...)
Affinity DataKi:  500nMAssay Description:Binding affinity against Opioid receptor kappa 1 using [3H]-U-69,593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50218796(CHEMBL557978 | oxymorphindole | OXYMORPHINDOLE CHL...)
Affinity DataKi:  661nMAssay Description:Binding affinity against Opioid receptor mu 1 using [3H][D-Ala2, MePhe4, Gly-ol5]-enkephalin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50039029(CHEMBL13470 | 3-[(4-Allyl-2,5-dimethyl-piperazin-1...)
Affinity DataKi:  1.30E+3nMAssay Description:Binding affinity against Opioid receptor mu 1 using [3H][D-Ala2, MePhe4, Gly-ol5]-enkephalin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50039029(CHEMBL13470 | 3-[(4-Allyl-2,5-dimethyl-piperazin-1...)
Affinity DataKi:  1.35E+3nMAssay Description:Binding affinity against Opioid receptor kappa 1 using [3H]-U-69,593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50061062(3-((4aS,11aR)-2-Ethyl-1,2,3,4,5,6,11,11a-octahydro...)
Affinity DataKi:  1.63E+3nMAssay Description:Binding affinity against Opioid receptor mu 1 using [3H][D-Ala2, MePhe4, Gly-ol5]-enkephalin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50061062(3-((4aS,11aR)-2-Ethyl-1,2,3,4,5,6,11,11a-octahydro...)
Affinity DataKi:  2.09E+3nMAssay Description:Binding affinity against Opioid receptor mu 1 using [3H][D-Ala2, MePhe4, Gly-ol5]-enkephalin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50061061((4aR,8aS)-6-Ethyl-8a-(3-hydroxy-phenyl)-3-methyl-4...)
Affinity DataKi:  3.53E+3nMAssay Description:Binding affinity against Opioid receptor delta 1 using [3H][D-Ala2, D-Leu5]-enkephalin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50061061((4aR,8aS)-6-Ethyl-8a-(3-hydroxy-phenyl)-3-methyl-4...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity against Opioid receptor mu 1 using [3H][D-Ala2, MePhe4, Gly-ol5]-enkephalin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50061061((4aR,8aS)-6-Ethyl-8a-(3-hydroxy-phenyl)-3-methyl-4...)
Affinity DataKi:  6.00E+3nMAssay Description:Binding affinity against Opioid receptor kappa 1 using [3H]-U-69,593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50061061((4aR,8aS)-6-Ethyl-8a-(3-hydroxy-phenyl)-3-methyl-4...)
Affinity DataKi:  6.01E+3nMAssay Description:Binding affinity against Opioid receptor kappa 1 using [3H]-U-69,593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed