Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50036541
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50059717(4-Furan-3-yl-7-[6-(4-hydroxy-tetrahydro-pyran-4-yl...)
Affinity DataIC50: 15nMAssay Description:Compound was evaluated for the potency to inhibit oxidation of arachidonic acid by human recombinant 5-Lipoxygenase using a spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50059715(4-Furan-3-yl-7-[6-(3-hydroxy-6,8-dioxa-bicyclo[3.2...)
Affinity DataIC50: 20nMAssay Description:Inhibition of oxidation of arachidonic acid by human 5-Lipoxygenase using spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50053554(4-Furan-3-yl-7-[3-(4-hydroxy-tetrahydro-pyran-4-yl...)
Affinity DataIC50: 30nMAssay Description:Inhibition of oxidation of arachidonic acid by human 5-Lipoxygenase using spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50059722(4-Furan-3-yl-7-[4-(4-hydroxy-tetrahydro-pyran-4-yl...)
Affinity DataIC50: 70nMAssay Description:Inhibition of oxidation of arachidonic acid by human 5-Lipoxygenase using spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50059720(4-Furan-3-yl-7-[6-(3-hydroxy-6,8-dioxa-bicyclo[3.2...)
Affinity DataIC50: 80nMAssay Description:Inhibition of oxidation of arachidonic acid by human 5-Lipoxygenase using spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50059714(4-Furan-3-yl-7-[5-(4-hydroxy-tetrahydro-pyran-4-yl...)
Affinity DataIC50: 100nMAssay Description:Inhibition of oxidation of arachidonic acid by human 5-Lipoxygenase using spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50059719(4-Furan-3-yl-7-[2-(4-hydroxy-tetrahydro-pyran-4-yl...)
Affinity DataIC50: 160nMAssay Description:Inhibition of oxidation of arachidonic acid by human 5-Lipoxygenase using spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50053548(L-702-539 | 4-Furan-3-yl-7-[3-(3-hydroxy-6,8-dioxa...)
Affinity DataIC50: 190nMAssay Description:Inhibition of oxidation of arachidonic acid by human 5-Lipoxygenase using spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50059721(4-Furan-3-yl-7-[2-(4-hydroxy-tetrahydro-pyran-4-yl...)
Affinity DataIC50: 350nMAssay Description:Compound was evaluated for the potency to inhibit oxidation of arachidonic acid by human recombinant 5-Lipoxygenase using a spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50059718(4-Furan-3-yl-7-[7-(4-hydroxy-tetrahydro-pyran-4-yl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of oxidation of arachidonic acid by human 5-Lipoxygenase using spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of oxidation of arachidonic acid by human 5-Lipoxygenase using spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029559(L-686708 | MK-591 | 3-[3-tert-Butylsulfanyl-1-(4-c...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of oxidation of arachidonic acid by human 5-Lipoxygenase using spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed