Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50007131
TargetIntegrin alpha-IIb/beta-3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50058928([6-(4-Carbamimidoyl-phenylcarbamoyl)-1-oxo-3,4-dih...)
Affinity DataIC50: 3nMAssay Description:Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50058924([6-(4-Carbamimidoyl-phenylethynyl)-1-oxo-3,4-dihyd...)
Affinity DataIC50: 33nMAssay Description:Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50058908({6-[(E)-2-(4-Carbamimidoyl-phenyl)-vinyl]-1-oxo-3,...)
Affinity DataIC50: 48nMAssay Description:Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50058914([6-(4-Carbamimidoyl-benzoylamino)-1-oxo-3,4-dihydr...)
Affinity DataIC50: 76nMAssay Description:Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50058920({6-[2-(4-Carbamimidoyl-phenyl)-ethyl]-1-oxo-3,4-di...)
Affinity DataIC50: 110nMAssay Description:Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50058910({6-[(Z)-2-(4-Carbamimidoyl-phenyl)-vinyl]-1-oxo-3,...)
Affinity DataIC50: 290nMAssay Description:Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50058911([6-(4-Carbamimidoyl-benzyloxy)-1-oxo-3,4-dihydro-1...)
Affinity DataIC50: 600nMAssay Description:Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50058907([1-Oxo-6-(4-piperidin-4-yl-butoxy)-3,4-dihydro-1H-...)
Affinity DataIC50: 1.80E+3nMAssay Description:Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50058916([6-(4-Guanidinomethyl-benzyloxy)-1-oxo-3,4-dihydro...)
Affinity DataIC50: 4.00E+3nMAssay Description:Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50058930([7-(4-Carbamimidoyl-benzyloxy)-1-oxo-3,4-dihydro-1...)
Affinity DataIC50: 4.00E+3nMAssay Description:Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50058913({6-[2-(4-Carbamimidoyl-phenyl)-ethoxy]-1-oxo-3,4-d...)
Affinity DataIC50: 6.00E+3nMAssay Description:Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50058923([1-Oxo-6-(3-piperidin-4-yl-propoxy)-3,4-dihydro-1H...)
Affinity DataIC50: 6.00E+3nMAssay Description:Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50058926([6-(5-Guanidino-pentyloxy)-1-oxo-3,4-dihydro-1H-is...)
Affinity DataIC50: 9.00E+3nMAssay Description:Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50058931([6-(4-Guanidino-butoxy)-1-oxo-3,4-dihydro-1H-isoqu...)
Affinity DataIC50: 1.00E+4nMAssay Description:Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50058917([1-Oxo-6-(2-piperidin-4-yl-ethoxy)-3,4-dihydro-1H-...)
Affinity DataIC50: 1.10E+4nMAssay Description:Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50058925([6-(4-Aminomethyl-benzyloxy)-1-oxo-3,4-dihydro-1H-...)
Affinity DataIC50: 1.20E+4nMAssay Description:Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50058909([6-(6-Guanidino-hexyloxy)-1-oxo-3,4-dihydro-1H-iso...)
Affinity DataIC50: 1.20E+4nMAssay Description:Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50058918([6-(3-Guanidinomethyl-benzyloxy)-1-oxo-3,4-dihydro...)
Affinity DataIC50: 1.40E+4nMAssay Description:Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50058929([6-(4-Amino-butoxy)-1-oxo-3,4-dihydro-1H-isoquinol...)
Affinity DataIC50: 1.80E+4nMAssay Description:Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50058921([6-(6-Amino-hexyloxy)-1-oxo-3,4-dihydro-1H-isoquin...)
Affinity DataIC50: 1.90E+4nMAssay Description:Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50058932([6-(5-Amino-pentyloxy)-1-oxo-3,4-dihydro-1H-isoqui...)
Affinity DataIC50: 2.80E+4nMAssay Description:Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50058915([6-(3-Guanidino-propoxy)-1-oxo-3,4-dihydro-1H-isoq...)
Affinity DataIC50: 4.40E+4nMAssay Description:Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50058927([7-(4-Guanidino-butoxy)-1-oxo-3,4-dihydro-1H-isoqu...)
Affinity DataIC50: 4.60E+4nMAssay Description:Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50058912([6-(3-Amino-propoxy)-1-oxo-3,4-dihydro-1H-isoquino...)
Affinity DataIC50: 4.80E+4nMAssay Description:Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50058919([1-Oxo-6-(piperidin-4-ylmethoxy)-3,4-dihydro-1H-is...)
Affinity DataIC50: 5.50E+4nMAssay Description:Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50058922([6-(3-Aminomethyl-benzyloxy)-1-oxo-3,4-dihydro-1H-...)
Affinity DataIC50: 7.70E+4nMAssay Description:Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed