Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50007114
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029766BDBM50029766(2,4-DIAMINO-5-METHYL-6-[(3,4,5-TRIMETHOXY-N-METHYL...)
Affinity DataIC50: 0.850nMAssay Description:Inhibitory concentration against Toxoplasma gondii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18224BDBM18224(6-[(2,5-dimethoxyphenyl)methyl]-5-methylpyrido[2,3...)
Affinity DataIC50: 1.5nMAssay Description:Inhibitory concentration against Rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18268BDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration against Rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029766BDBM50029766(2,4-DIAMINO-5-METHYL-6-[(3,4,5-TRIMETHOXY-N-METHYL...)
Affinity DataIC50: 7.60nMAssay Description:Inhibitory concentration against Rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18268BDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against Toxoplasma gondii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029766BDBM50029766(2,4-DIAMINO-5-METHYL-6-[(3,4,5-TRIMETHOXY-N-METHYL...)
Affinity DataIC50: 13nMAssay Description:Inhibitory concentration against Pneumocystis carinii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18224BDBM18224(6-[(2,5-dimethoxyphenyl)methyl]-5-methylpyrido[2,3...)
Affinity DataIC50: 17nMAssay Description:Inhibitory concentration against Toxoplasma gondii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18224BDBM18224(6-[(2,5-dimethoxyphenyl)methyl]-5-methylpyrido[2,3...)
Affinity DataIC50: 31nMAssay Description:Inhibitory concentration against Pneumocystis carinii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18268BDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)
Affinity DataIC50: 42nMAssay Description:Inhibitory concentration against Pneumocystis carinii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50058517BDBM50058517(2,4-Diamino-7-(3,4,5-trimethoxy-phenyl)-7H-1,3,7,1...)
Affinity DataIC50: 86nMAssay Description:Inhibitory concentration against Rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50058520BDBM50058520(7-(3,4,5-Trimethoxy-phenyl)-4b,5,6,7,8,8a,9,10-oct...)
Affinity DataIC50: 160nMAssay Description:Inhibitory concentration against Rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50058519BDBM50058519(2,4-Diamino-7-(3,4,5-trimethoxy-phenyl)-6,7-dihydr...)
Affinity DataIC50: 240nMAssay Description:Inhibitory concentration against Rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50058520BDBM50058520(7-(3,4,5-Trimethoxy-phenyl)-4b,5,6,7,8,8a,9,10-oct...)
Affinity DataIC50: 290nMAssay Description:Inhibitory concentration against Toxoplasma gondii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50058522BDBM50058522(Trifluoro-acetate2,4-diamino-7-(3,4,5-trimethoxy-p...)
Affinity DataIC50: 470nMAssay Description:Inhibitory concentration against Rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50058521BDBM50058521(2,4-Diamino-7-(2,6-dichloro-3,4,5-trimethoxy-pheny...)
Affinity DataIC50: 500nMAssay Description:Inhibitory concentration against Rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50058517BDBM50058517(2,4-Diamino-7-(3,4,5-trimethoxy-phenyl)-7H-1,3,7,1...)
Affinity DataIC50: 520nMAssay Description:Inhibitory concentration against Toxoplasma gondii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50058522BDBM50058522(Trifluoro-acetate2,4-diamino-7-(3,4,5-trimethoxy-p...)
Affinity DataIC50: 760nMAssay Description:Inhibitory concentration against Toxoplasma gondii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50058521BDBM50058521(2,4-Diamino-7-(2,6-dichloro-3,4,5-trimethoxy-pheny...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against Pneumocystis carinii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50058519BDBM50058519(2,4-Diamino-7-(3,4,5-trimethoxy-phenyl)-6,7-dihydr...)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibitory concentration against Toxoplasma gondii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50058520BDBM50058520(7-(3,4,5-Trimethoxy-phenyl)-4b,5,6,7,8,8a,9,10-oct...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibitory concentration against Pneumocystis carinii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50058518BDBM50058518(7-(3,4,5-Trimethoxy-phenyl)-5,6,7,8-tetrahydro-1,3...)
Affinity DataIC50: 2.27E+3nMAssay Description:Inhibitory concentration against Pneumocystis carinii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50058521BDBM50058521(2,4-Diamino-7-(2,6-dichloro-3,4,5-trimethoxy-pheny...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibitory concentration against Toxoplasma gondii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50058517BDBM50058517(2,4-Diamino-7-(3,4,5-trimethoxy-phenyl)-7H-1,3,7,1...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibitory concentration against Pneumocystis carinii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50058518BDBM50058518(7-(3,4,5-Trimethoxy-phenyl)-5,6,7,8-tetrahydro-1,3...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibitory concentration against Rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50058519BDBM50058519(2,4-Diamino-7-(3,4,5-trimethoxy-phenyl)-6,7-dihydr...)
Affinity DataIC50: 4.28E+3nMAssay Description:Inhibitory concentration against Pneumocystis carinii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50058522BDBM50058522(Trifluoro-acetate2,4-diamino-7-(3,4,5-trimethoxy-p...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibitory concentration against Pneumocystis carinii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50058523BDBM50058523(2,4-Diamino-7-(3,4,5-trimethoxy-phenyl)-6,7,8,10-t...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory concentration against Pneumocystis carinii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50058523BDBM50058523(2,4-Diamino-7-(3,4,5-trimethoxy-phenyl)-6,7,8,10-t...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory concentration against Rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed