Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50007053
TargetProtein kinase C beta type(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50057514(13-Hydroxymethyl-10-isopropyl-9-methyl-5-octyl-3,9...)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]- PDBu from recombinant PKC beta expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50057514(13-Hydroxymethyl-10-isopropyl-9-methyl-5-octyl-3,9...)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]- PDBu from recombinant PKC alpha expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50057514(13-Hydroxymethyl-10-isopropyl-9-methyl-5-octyl-3,9...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]- PDBu from recombinant PKC delta expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50057512((1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-4a,7b-dihydroxy-3-...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of [3H]PDBu binding to PKC delta wild typeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50057514(13-Hydroxymethyl-10-isopropyl-9-methyl-5-octyl-3,9...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]- PDBu from recombinant PKC epsilon expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C gamma type(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50057514(13-Hydroxymethyl-10-isopropyl-9-methyl-5-octyl-3,9...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]- PDBu from recombinant PKC gamma expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50057511(CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...)
Affinity DataKi:  6.10nMAssay Description:Displacement of [3H]- PDBu from recombinant PKC beta expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50057511(CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...)
Affinity DataKi:  8.20nMAssay Description:Displacement of [3H]- PDBu from recombinant PKC delta expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50057509(8-Dec-1-ynyl-5-hydroxymethyl-2-isopropyl-1-methyl-...)
Affinity DataKi:  11nMAssay Description:Inhibition of [3H]PDBu binding to PKC delta wild typeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50057511(CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]- PDBu from recombinant PKC alpha expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50057512((1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-4a,7b-dihydroxy-3-...)
Affinity DataKi:  12nMAssay Description:Inhibition of [3H]PDBu binding to PKC delta mutant Leu 20-GlyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50057509(8-Dec-1-ynyl-5-hydroxymethyl-2-isopropyl-1-methyl-...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]- PDBu from recombinant PKC alpha expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50057509(8-Dec-1-ynyl-5-hydroxymethyl-2-isopropyl-1-methyl-...)
Affinity DataKi:  17.4nMAssay Description:Displacement of [3H]- PDBu from recombinant PKC beta expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C gamma type(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50057511(CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...)
Affinity DataKi:  19.4nMAssay Description:Displacement of [3H]- PDBu from recombinant PKC gamma expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50057511(CHEMBL27266 | 13-Hydroxymethyl-10-isopropyl-9-meth...)
Affinity DataKi:  21.9nMAssay Description:Displacement of [3H]- PDBu from recombinant PKC epsilon expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50057512((1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-4a,7b-dihydroxy-3-...)
Affinity DataKi:  22nMAssay Description:Inhibition of [3H]-PDBu binding to PKC delta mutant Gln 27-ValMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C gamma type(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50057509(8-Dec-1-ynyl-5-hydroxymethyl-2-isopropyl-1-methyl-...)
Affinity DataKi:  40.7nMAssay Description:Displacement of [3H]- PDBu from recombinant PKC gamma expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50057510((2S,5S)-8-Decyl-5-hydroxymethyl-2-isopropyl-1-meth...)
Affinity DataKi:  47nMAssay Description:Displacement of [3H]- PDBu from recombinant PKC alpha expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50057510((2S,5S)-8-Decyl-5-hydroxymethyl-2-isopropyl-1-meth...)
Affinity DataKi:  58.2nMAssay Description:Displacement of [3H]- PDBu from recombinant PKC beta expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50057512((1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-4a,7b-dihydroxy-3-...)
Affinity DataKi:  100nMAssay Description:Inhibition of [3H]PDBu binding to PKC delta mutant Pro 11-GlyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50057509(8-Dec-1-ynyl-5-hydroxymethyl-2-isopropyl-1-methyl-...)
Affinity DataKi:  122nMAssay Description:Displacement of [3H]- PDBu from recombinant PKC delta expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50057509(8-Dec-1-ynyl-5-hydroxymethyl-2-isopropyl-1-methyl-...)
Affinity DataKi:  134nMAssay Description:Inhibition of [3H]PDBu binding to PKC delta mutant Leu 20-GlyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C gamma type(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50057510((2S,5S)-8-Decyl-5-hydroxymethyl-2-isopropyl-1-meth...)
Affinity DataKi:  140nMAssay Description:Displacement of [3H]- PDBu from recombinant PKC gamma expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50057509(8-Dec-1-ynyl-5-hydroxymethyl-2-isopropyl-1-methyl-...)
Affinity DataKi:  142nMAssay Description:Displacement of [3H]- PDBu from recombinant PKC epsilon expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50057510((2S,5S)-8-Decyl-5-hydroxymethyl-2-isopropyl-1-meth...)
Affinity DataKi:  185nMAssay Description:Displacement of [3H]- PDBu from recombinant PKC delta expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50057510((2S,5S)-8-Decyl-5-hydroxymethyl-2-isopropyl-1-meth...)
Affinity DataKi:  187nMAssay Description:Displacement of [3H]- PDBu from recombinant PKC epsilon expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50057513(benzolactam-V8 | (2S,5S)-5-Hydroxymethyl-2-isoprop...)
Affinity DataKi:  334nMAssay Description:Displacement of [3H]- PDBu from recombinant PKC alpha expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50057509(8-Dec-1-ynyl-5-hydroxymethyl-2-isopropyl-1-methyl-...)
Affinity DataKi:  730nMAssay Description:Inhibition of [3H]PDBu binding to PKC delta mutant Pro 11-GlyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50057509(8-Dec-1-ynyl-5-hydroxymethyl-2-isopropyl-1-methyl-...)
Affinity DataKi:  933nMAssay Description:Inhibition of [3H]-PDBu binding to PKC delta mutant Gln 27-ValMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed