Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50007041
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18224(6-[(2,5-dimethoxyphenyl)methyl]-5-methylpyrido[2,3...)
Affinity DataIC50: 1nMAssay Description:Inhibition against Dihydrofolate reductase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataIC50: 1nMAssay Description:Inhibition against Dihydrofolate reductase in Pneumocystis cariniiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataIC50: 3nMAssay Description:Inhibition against Dihydrofolate reductase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)
Affinity DataIC50: 3nMAssay Description:Inhibition against Dihydrofolate reductase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18224(6-[(2,5-dimethoxyphenyl)methyl]-5-methylpyrido[2,3...)
Affinity DataIC50: 10nMAssay Description:Inhibition against Dihydrofolate reductase in Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)
Affinity DataIC50: 10nMAssay Description:Inhibition against Dihydrofolate reductase in Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataIC50: 14nMAssay Description:Inhibition against Dihydrofolate reductase in Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18224(6-[(2,5-dimethoxyphenyl)methyl]-5-methylpyrido[2,3...)
Affinity DataIC50: 38nMAssay Description:Inhibition against Dihydrofolate reductase in Pneumocystis cariniiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035269(2-{4-[(2,4-Diamino-7H-pyrrolo[2,3-d]pyrimidin-5-yl...)
Affinity DataIC50: 38nMAssay Description:Inhibition against Dihydrofolate reductase in Pneumocystis cariniiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)
Affinity DataIC50: 42nMAssay Description:Inhibition against Dihydrofolate reductase in Pneumocystis cariniiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057314(2-({4-[(2,4-Diamino-7H-pyrrolo[2,3-d]pyrimidin-5-y...)
Affinity DataIC50: 44nMAssay Description:Inhibition against Dihydrofolate reductase in Pneumocystis cariniiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035269(2-{4-[(2,4-Diamino-7H-pyrrolo[2,3-d]pyrimidin-5-yl...)
Affinity DataIC50: 44nMAssay Description:Inhibition against Dihydrofolate reductase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057314(2-({4-[(2,4-Diamino-7H-pyrrolo[2,3-d]pyrimidin-5-y...)
Affinity DataIC50: 60nMAssay Description:Inhibition against Dihydrofolate reductase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057314(2-({4-[(2,4-Diamino-7H-pyrrolo[2,3-d]pyrimidin-5-y...)
Affinity DataIC50: 150nMAssay Description:Inhibition against Dihydrofolate reductase in Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035269(2-{4-[(2,4-Diamino-7H-pyrrolo[2,3-d]pyrimidin-5-yl...)
Affinity DataIC50: 210nMAssay Description:Inhibition against Dihydrofolate reductase in Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057315(5-(Naphthalen-1-ylsulfanylmethyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50: 810nMAssay Description:Inhibition against Dihydrofolate reductase in Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057312(5-[(Methyl-naphthalen-1-yl-amino)-methyl]-7H-pyrro...)
Affinity DataIC50: 870nMAssay Description:Inhibition against Dihydrofolate reductase in Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057313(5-{[(3,4-Dichloro-phenyl)-methyl-amino]-methyl}-7H...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition against Dihydrofolate reductase in Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035274(5-(Naphthalen-1-ylaminomethyl)-7H-pyrrolo[2,3-d]py...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition against Dihydrofolate reductase in Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035273(5-[(3,4-Dichloro-phenylamino)-methyl]-7H-pyrrolo[2...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition against Dihydrofolate reductase in Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035271(5-[(2,5-Dimethoxy-phenylamino)-methyl]-7H-pyrrolo[...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition against Dihydrofolate reductase in Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057311(5-(3,4-Dimethoxy-phenylsulfanylmethyl)-7H-pyrrolo[...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition against Dihydrofolate reductase in Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18069(CHEMBL22 | TMP | Trimethoprim (TMP) | 5-[(3,4,5-tr...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition against Dihydrofolate reductase in Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057315(5-(Naphthalen-1-ylsulfanylmethyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition against Dihydrofolate reductase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057313(5-{[(3,4-Dichloro-phenyl)-methyl-amino]-methyl}-7H...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition against Dihydrofolate reductase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057316(5-{[(2,5-Dimethoxy-phenyl)-methyl-amino]-methyl}-7...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition against Dihydrofolate reductase in Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057317(5-((3,4-dichlorophenylthio)methyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition against Dihydrofolate reductase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057312(5-[(Methyl-naphthalen-1-yl-amino)-methyl]-7H-pyrro...)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition against Dihydrofolate reductase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057318(5-(Naphthalen-2-ylsulfanylmethyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition against Dihydrofolate reductase in Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057315(5-(Naphthalen-1-ylsulfanylmethyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition against Dihydrofolate reductase in Pneumocystis cariniiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057311(5-(3,4-Dimethoxy-phenylsulfanylmethyl)-7H-pyrrolo[...)
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition against Dihydrofolate reductase in Pneumocystis cariniiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057317(5-((3,4-dichlorophenylthio)methyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition against Dihydrofolate reductase in Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057316(5-{[(2,5-Dimethoxy-phenyl)-methyl-amino]-methyl}-7...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition against Dihydrofolate reductase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057316(5-{[(2,5-Dimethoxy-phenyl)-methyl-amino]-methyl}-7...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition against Dihydrofolate reductase in Pneumocystis cariniiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18069(CHEMBL22 | TMP | Trimethoprim (TMP) | 5-[(3,4,5-tr...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition against Dihydrofolate reductase in Pneumocystis cariniiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035273(5-[(3,4-Dichloro-phenylamino)-methyl]-7H-pyrrolo[2...)
Affinity DataIC50: 1.44E+4nMAssay Description:Inhibition against Dihydrofolate reductase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057311(5-(3,4-Dimethoxy-phenylsulfanylmethyl)-7H-pyrrolo[...)
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition against Dihydrofolate reductase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057313(5-{[(3,4-Dichloro-phenyl)-methyl-amino]-methyl}-7H...)
Affinity DataIC50: 2.83E+4nMAssay Description:Inhibition against Dihydrofolate reductase in Pneumocystis cariniiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035273(5-[(3,4-Dichloro-phenylamino)-methyl]-7H-pyrrolo[2...)
Affinity DataIC50: 3.53E+4nMAssay Description:Inhibition against Dihydrofolate reductase in Pneumocystis cariniiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035271(5-[(2,5-Dimethoxy-phenylamino)-methyl]-7H-pyrrolo[...)
Affinity DataIC50: 4.57E+4nMAssay Description:Inhibition against Dihydrofolate reductase in Pneumocystis cariniiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057317(5-((3,4-dichlorophenylthio)methyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 5.85E+4nMAssay Description:Inhibition against Dihydrofolate reductase in Pneumocystis cariniiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035274(5-(Naphthalen-1-ylaminomethyl)-7H-pyrrolo[2,3-d]py...)
Affinity DataIC50: 5.93E+4nMAssay Description:Inhibition against Dihydrofolate reductase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057318(5-(Naphthalen-2-ylsulfanylmethyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50: 8.29E+4nMAssay Description:Inhibition against Dihydrofolate reductase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18069(CHEMBL22 | TMP | Trimethoprim (TMP) | 5-[(3,4,5-tr...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition against Dihydrofolate reductase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035271(5-[(2,5-Dimethoxy-phenylamino)-methyl]-7H-pyrrolo[...)
Affinity DataIC50: 1.56E+5nMAssay Description:Inhibition against Dihydrofolate reductase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057312(5-[(Methyl-naphthalen-1-yl-amino)-methyl]-7H-pyrro...)
Affinity DataIC50: 2.09E+5nMAssay Description:Inhibition against Dihydrofolate reductase in Pneumocystis cariniiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035274(5-(Naphthalen-1-ylaminomethyl)-7H-pyrrolo[2,3-d]py...)
Affinity DataIC50: 3.07E+5nMAssay Description:Inhibition against Dihydrofolate reductase in Pneumocystis cariniiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057318(5-(Naphthalen-2-ylsulfanylmethyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50: 9.29E+5nMAssay Description:Inhibition against Dihydrofolate reductase in Pneumocystis cariniiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed