Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50006968
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18224(6-[(2,5-dimethoxyphenyl)methyl]-5-methylpyrido[2,3...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of Dihydrofolate Reductase of Rat Liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50029772(5-Methyl-6-[(3,4,5-trimethoxy-phenylamino)-methyl]...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Dihydrofolate Reductase of Rat Liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50029772(5-Methyl-6-[(3,4,5-trimethoxy-phenylamino)-methyl]...)
Affinity DataIC50: 10nMAssay Description:Inhibition of Dihydrofolate Reductase of Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18224(6-[(2,5-dimethoxyphenyl)methyl]-5-methylpyrido[2,3...)
Affinity DataIC50: 11nMAssay Description:Inhibition of Dihydrofolate Reductase of Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50034938(6-[(2,5-Dimethoxy-phenylamino)-methyl]-5-methyl-py...)
Affinity DataIC50: 16nMAssay Description:Inhibition of Dihydrofolate Reductase of Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056246(6-[(2,5-Dimethoxy-4-pyrrol-1-yl-phenylamino)-methy...)
Affinity DataIC50: 33nMAssay Description:Inhibition of Dihydrofolate Reductase of Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18224(6-[(2,5-dimethoxyphenyl)methyl]-5-methylpyrido[2,3...)
Affinity DataIC50: 38nMAssay Description:Inhibition of Dihydrofolate Reductase of Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50029772(5-Methyl-6-[(3,4,5-trimethoxy-phenylamino)-methyl]...)
Affinity DataIC50: 42nMAssay Description:Inhibition of Dihydrofolate Reductase of Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50034938(6-[(2,5-Dimethoxy-phenylamino)-methyl]-5-methyl-py...)
Affinity DataIC50: 46nMAssay Description:Inhibition of Dihydrofolate Reductase of Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056242(6-(4-Methoxy-2,3-dihydro-indol-1-ylmethyl)-5-methy...)
Affinity DataIC50: 48nMAssay Description:Inhibition of Dihydrofolate Reductase of Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056241(6-(5,6-Dimethoxy-2,3-dihydro-indol-1-ylmethyl)-5-m...)
Affinity DataIC50: 49nMAssay Description:Inhibition of Dihydrofolate Reductase of Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056243(6-(5-Methoxy-2,3-dihydro-indol-1-ylmethyl)-5-methy...)
Affinity DataIC50: 57nMAssay Description:Inhibition of Dihydrofolate Reductase of Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056240(6-[(4-Methoxy-biphenyl-3-ylamino)-methyl]-5-methyl...)
Affinity DataIC50: 68nMAssay Description:Inhibition of Dihydrofolate Reductase of Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056245(5-Methyl-6-[(2,3,5,6-tetramethyl-4-pyrrol-1-yl-phe...)
Affinity DataIC50: 75nMAssay Description:Inhibition of Dihydrofolate Reductase of Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056238(6-(5-Methoxy-indol-1-ylmethyl)-5-methyl-pyrido[2,3...)
Affinity DataIC50: 77nMAssay Description:Inhibition of Dihydrofolate Reductase of Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056244(6-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-ylme...)
Affinity DataIC50: 110nMAssay Description:Inhibition of Dihydrofolate Reductase of Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056244(6-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-ylme...)
Affinity DataIC50: 130nMAssay Description:Inhibition of Dihydrofolate Reductase of Rat Liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50034938(6-[(2,5-Dimethoxy-phenylamino)-methyl]-5-methyl-py...)
Affinity DataIC50: 130nMAssay Description:Inhibition of Dihydrofolate Reductase of Rat Liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056242(6-(4-Methoxy-2,3-dihydro-indol-1-ylmethyl)-5-methy...)
Affinity DataIC50: 150nMAssay Description:Inhibition of Dihydrofolate Reductase of Rat Liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056243(6-(5-Methoxy-2,3-dihydro-indol-1-ylmethyl)-5-methy...)
Affinity DataIC50: 170nMAssay Description:Inhibition of Dihydrofolate Reductase of Rat Liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056245(5-Methyl-6-[(2,3,5,6-tetramethyl-4-pyrrol-1-yl-phe...)
Affinity DataIC50: 170nMAssay Description:Inhibition of Dihydrofolate Reductase of Rat Liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056241(6-(5,6-Dimethoxy-2,3-dihydro-indol-1-ylmethyl)-5-m...)
Affinity DataIC50: 230nMAssay Description:Inhibition of Dihydrofolate Reductase of Rat Liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056246(6-[(2,5-Dimethoxy-4-pyrrol-1-yl-phenylamino)-methy...)
Affinity DataIC50: 230nMAssay Description:Inhibition of Dihydrofolate Reductase of Rat Liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056243(6-(5-Methoxy-2,3-dihydro-indol-1-ylmethyl)-5-methy...)
Affinity DataIC50: 250nMAssay Description:Inhibition of Dihydrofolate Reductase of Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056242(6-(4-Methoxy-2,3-dihydro-indol-1-ylmethyl)-5-methy...)
Affinity DataIC50: 290nMAssay Description:Inhibition of Dihydrofolate Reductase of Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056246(6-[(2,5-Dimethoxy-4-pyrrol-1-yl-phenylamino)-methy...)
Affinity DataIC50: 350nMAssay Description:Inhibition of Dihydrofolate Reductase of Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056241(6-(5,6-Dimethoxy-2,3-dihydro-indol-1-ylmethyl)-5-m...)
Affinity DataIC50: 410nMAssay Description:Inhibition of Dihydrofolate Reductase of Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056240(6-[(4-Methoxy-biphenyl-3-ylamino)-methyl]-5-methyl...)
Affinity DataIC50: 440nMAssay Description:Inhibition of Dihydrofolate Reductase of Rat Liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056238(6-(5-Methoxy-indol-1-ylmethyl)-5-methyl-pyrido[2,3...)
Affinity DataIC50: 470nMAssay Description:Inhibition of Dihydrofolate Reductase of Rat Liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50029763(Epiroprim | TCMDC-137295 | 5-(3,5-Diethoxy-4-pyrro...)
Affinity DataIC50: 480nMAssay Description:Inhibition of Dihydrofolate Reductase of Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056238(6-(5-Methoxy-indol-1-ylmethyl)-5-methyl-pyrido[2,3...)
Affinity DataIC50: 570nMAssay Description:Inhibition of Dihydrofolate Reductase of Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056239(6-[(4,5-Dimethoxy-2-pyrrol-1-yl-phenylamino)-methy...)
Affinity DataIC50: 600nMAssay Description:Inhibition of Dihydrofolate Reductase of Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056245(5-Methyl-6-[(2,3,5,6-tetramethyl-4-pyrrol-1-yl-phe...)
Affinity DataIC50: 620nMAssay Description:Inhibition of Dihydrofolate Reductase of Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056240(6-[(4-Methoxy-biphenyl-3-ylamino)-methyl]-5-methyl...)
Affinity DataIC50: 640nMAssay Description:Inhibition of Dihydrofolate Reductase of Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056244(6-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-ylme...)
Affinity DataIC50: 850nMAssay Description:Inhibition of Dihydrofolate Reductase of Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056239(6-[(4,5-Dimethoxy-2-pyrrol-1-yl-phenylamino)-methy...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of Dihydrofolate Reductase of Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50029763(Epiroprim | TCMDC-137295 | 5-(3,5-Diethoxy-4-pyrro...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of Dihydrofolate Reductase of Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18069(CHEMBL22 | TMP | Trimethoprim (TMP) | 5-[(3,4,5-tr...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of Dihydrofolate Reductase of Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056239(6-[(4,5-Dimethoxy-2-pyrrol-1-yl-phenylamino)-methy...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of Dihydrofolate Reductase of Rat Liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18069(CHEMBL22 | TMP | Trimethoprim (TMP) | 5-[(3,4,5-tr...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of Dihydrofolate Reductase of Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50029763(Epiroprim | TCMDC-137295 | 5-(3,5-Diethoxy-4-pyrro...)
Affinity DataIC50: 3.32E+4nMAssay Description:Inhibition of Dihydrofolate Reductase of Rat Liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18069(CHEMBL22 | TMP | Trimethoprim (TMP) | 5-[(3,4,5-tr...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of Dihydrofolate Reductase of Rat Liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)