Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 524
TargetTyrosine-protein kinase transforming protein Src(Avian sarcoma virus)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3354(2,2 -Diselenobis[N,1-dimethyl-1H-indole-3-carboxam...)
Affinity DataIC50: 400nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3361((2R)-2-amino-3-[2-({3-[(2R)-2-amino-2-(benzylcarba...)
Affinity DataIC50: 900nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3362((2S)-2-amino-3-[2-({3-[(2S)-2-amino-2-(benzylcarba...)
Affinity DataIC50: 1.30E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase transforming protein Src(Avian sarcoma virus)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3351(CHEMBL336174 | 2-amino-3-[2-({3-[2-amino-2-(benzyl...)
Affinity DataIC50: 1.50E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase transforming protein Src(Avian sarcoma virus)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3352(tert-butyl 2-({3-[(tert-butoxy)carbonyl]-1-methyl-...)
Affinity DataIC50: 1.50E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase transforming protein Src(Avian sarcoma virus)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3358(1-[2-(diethylamino)ethyl]-2-({1-[2-(diethylamino)e...)
Affinity DataIC50: 1.70E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase transforming protein Src(Avian sarcoma virus)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3355(N-[2-(diethylamino)ethyl]-2-[(3-{[2-(diethylamino)...)
Affinity DataIC50: 1.80E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase transforming protein Src(Avian sarcoma virus)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3361((2R)-2-amino-3-[2-({3-[(2R)-2-amino-2-(benzylcarba...)
Affinity DataIC50: 2.00E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase transforming protein Src(Avian sarcoma virus)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3353(2-[(3-carboxy-1-methyl-1H-indol-2-yl)diselanyl]-1-...)
Affinity DataIC50: 2.40E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase transforming protein Src(Avian sarcoma virus)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3356(2,2 -Diselenobis[N-methyl-1H-indole-3-carboxamide]...)
Affinity DataIC50: 2.80E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Mouse)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3355(N-[2-(diethylamino)ethyl]-2-[(3-{[2-(diethylamino)...)
Affinity DataIC50: 3.40E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3353(2-[(3-carboxy-1-methyl-1H-indol-2-yl)diselanyl]-1-...)
Affinity DataIC50: 3.50E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase transforming protein Src(Avian sarcoma virus)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3357(N-[2-(diethylamino)ethyl]-2-[(3-{[2-(diethylamino)...)
Affinity DataIC50: 3.60E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase transforming protein Src(Avian sarcoma virus)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3362((2S)-2-amino-3-[2-({3-[(2S)-2-amino-2-(benzylcarba...)
Affinity DataIC50: 3.80E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3357(N-[2-(diethylamino)ethyl]-2-[(3-{[2-(diethylamino)...)
Affinity DataIC50: 4.60E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3355(N-[2-(diethylamino)ethyl]-2-[(3-{[2-(diethylamino)...)
Affinity DataIC50: 4.70E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Mouse)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3354(2,2 -Diselenobis[N,1-dimethyl-1H-indole-3-carboxam...)
Affinity DataIC50: 4.70E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3354(2,2 -Diselenobis[N,1-dimethyl-1H-indole-3-carboxam...)
Affinity DataIC50: 6.10E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase transforming protein Src(Avian sarcoma virus)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3360((2R)-N-benzyl-3-[2-({3-[(2R)-2-(benzylcarbamoyl)-2...)
Affinity DataIC50: 6.20E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase transforming protein Src(Avian sarcoma virus)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3350(N,1-dimethyl-2-{[1-methyl-3-(methylcarbamoyl)-1H-i...)
Affinity DataIC50: 6.70E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3358(1-[2-(diethylamino)ethyl]-2-({1-[2-(diethylamino)e...)
Affinity DataIC50: 6.90E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3350(N,1-dimethyl-2-{[1-methyl-3-(methylcarbamoyl)-1H-i...)
Affinity DataIC50: 6.90E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3360((2R)-N-benzyl-3-[2-({3-[(2R)-2-(benzylcarbamoyl)-2...)
Affinity DataIC50: 7.00E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3351(CHEMBL336174 | 2-amino-3-[2-({3-[2-amino-2-(benzyl...)
Affinity DataIC50: 7.40E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Mouse)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3356(2,2 -Diselenobis[N-methyl-1H-indole-3-carboxamide]...)
Affinity DataIC50: 8.00E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Mouse)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3357(N-[2-(diethylamino)ethyl]-2-[(3-{[2-(diethylamino)...)
Affinity DataIC50: 1.28E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3356(2,2 -Diselenobis[N-methyl-1H-indole-3-carboxamide]...)
Affinity DataIC50: 1.30E+4nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Mouse)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3361((2R)-2-amino-3-[2-({3-[(2R)-2-amino-2-(benzylcarba...)
Affinity DataIC50: 1.41E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Mouse)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3353(2-[(3-carboxy-1-methyl-1H-indol-2-yl)diselanyl]-1-...)
Affinity DataIC50: 1.74E+4nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Mouse)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3362((2S)-2-amino-3-[2-({3-[(2S)-2-amino-2-(benzylcarba...)
Affinity DataIC50: 2.55E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Mouse)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3350(N,1-dimethyl-2-{[1-methyl-3-(methylcarbamoyl)-1H-i...)
Affinity DataIC50: 2.81E+4nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Mouse)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3352(tert-butyl 2-({3-[(tert-butoxy)carbonyl]-1-methyl-...)
Affinity DataIC50: 3.10E+4nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Mouse)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3360((2R)-N-benzyl-3-[2-({3-[(2R)-2-(benzylcarbamoyl)-2...)
Affinity DataIC50: 5.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Mouse)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3359((2R)-N-benzyl-3-[2-({3-[(2R)-2-(benzylcarbamoyl)-2...)
Affinity DataIC50: 5.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Mouse)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3358(1-[2-(diethylamino)ethyl]-2-({1-[2-(diethylamino)e...)
Affinity DataIC50: 5.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase transforming protein Src(Avian sarcoma virus)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3359((2R)-N-benzyl-3-[2-({3-[(2R)-2-(benzylcarbamoyl)-2...)
Affinity DataIC50: 5.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3359((2R)-N-benzyl-3-[2-({3-[(2R)-2-(benzylcarbamoyl)-2...)
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3352(tert-butyl 2-({3-[(tert-butoxy)carbonyl]-1-methyl-...)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed