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Found
50
Enz. Inhib. hit(s) with all data for entry = 5072
Target
5-hydroxytryptamine receptor 2A
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001885
(3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
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Affinity Data
Ki: 0.140nM
More data for this Ligand-Target Pair
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001885
(3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
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Affinity Data
Ki: 0.25nM
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Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001885
(3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
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Affinity Data
Ki: 0.300nM
More data for this Ligand-Target Pair
Target Info
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Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
5-hydroxytryptamine receptor 2A
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001786
(1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...)
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Affinity Data
Ki: 0.300nM
More data for this Ligand-Target Pair
Target Info
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM78433
(2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...)
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Affinity Data
Ki: 0.320nM
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM21398
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
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Affinity Data
Ki: 0.350nM
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Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50002338
(10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...)
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Affinity Data
Ki: 0.400nM
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Date in BDB:
2/24/2012
Entry Details
Article
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50005118
(3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-h...)
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Affinity Data
Ki: 0.640nM
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001888
([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...)
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Affinity Data
Ki: 0.660nM
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Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM21398
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
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Affinity Data
Ki: 0.840nM
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001786
(1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...)
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Affinity Data
Ki: 0.850nM
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001786
(1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...)
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Affinity Data
Ki: 0.950nM
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Target Info
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM79181
(cid_2913535 | TRIFLUOPERAZINE | SMR000059133 | MLS...)
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Affinity Data
Ki: 0.960nM
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Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001888
([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...)
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Affinity Data
Ki: 1.15nM
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Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
5-hydroxytryptamine receptor 2A
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50010594
(ISOCLOZAPINE | 2-Chloro-11-(4-methyl-piperazin-1-y...)
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Affinity Data
Ki: 1.45nM
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Target Info
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CHEMBL
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50002338
(10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...)
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Affinity Data
Ki: 1.5nM
More data for this Ligand-Target Pair
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Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM22869
(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
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Affinity Data
Ki: 1.60nM
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ChEBI
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM82479
(CAS_132539-06-1 | NSC_4585 | OLANZAPINE | USRE4934...)
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Affinity Data
Ki: 2nM
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ChEBI
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM82479
(CAS_132539-06-1 | NSC_4585 | OLANZAPINE | USRE4934...)
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Affinity Data
Ki: 3.70nM
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Target Info
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ChEBI
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM22871
(13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azat...)
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Affinity Data
Ki: 5.20nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50010594
(ISOCLOZAPINE | 2-Chloro-11-(4-methyl-piperazin-1-y...)
Copy SMILES
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Affinity Data
Ki: 5.80nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/24/2012
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50010594
(ISOCLOZAPINE | 2-Chloro-11-(4-methyl-piperazin-1-y...)
Copy SMILES
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Affinity Data
Ki: 5.80nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
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PC sid
Similars
In Depth
Date in BDB:
2/24/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
5-hydroxytryptamine receptor 2A
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM82479
(CAS_132539-06-1 | NSC_4585 | OLANZAPINE | USRE4934...)
Copy SMILES
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Affinity Data
Ki: 5.80nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50130290
(Moban | 3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,...)
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Affinity Data
Ki: 6nM
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Target Info
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ChEBI
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM22871
(13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azat...)
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Affinity Data
Ki: 7.80nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
5-hydroxytryptamine receptor 2A
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM22871
(13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azat...)
Copy SMILES
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Affinity Data
Ki: 10.2nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
5-hydroxytryptamine receptor 2A
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM22869
(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
Copy SMILES
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Affinity Data
Ki: 11nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
5-hydroxytryptamine receptor 2A
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM21398
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
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Affinity Data
Ki: 25nM
More data for this Ligand-Target Pair
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In Depth
Date in BDB:
2/24/2012
Entry Details
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Copy Entry DOI
PubMed
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Target
5-hydroxytryptamine receptor 2A
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50102325
(CHEMBL340801 | Perlapine | 6-(4-Methyl-piperazin-1...)
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Affinity Data
Ki: 30nM
More data for this Ligand-Target Pair
Target Info
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50026045
(CHEMBL22242 | 3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-...)
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Affinity Data
Ki: 30nM
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50102325
(CHEMBL340801 | Perlapine | 6-(4-Methyl-piperazin-1...)
Copy SMILES
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Affinity Data
Ki: 30nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM22869
(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
Copy SMILES
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Affinity Data
Ki: 44nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM79181
(cid_2913535 | TRIFLUOPERAZINE | SMR000059133 | MLS...)
Copy SMILES
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Affinity Data
Ki: 44nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM78433
(2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...)
Copy SMILES
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Affinity Data
Ki: 50nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50102325
(CHEMBL340801 | Perlapine | 6-(4-Methyl-piperazin-1...)
Copy SMILES
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Affinity Data
Ki: 60nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/24/2012
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
5-hydroxytryptamine receptor 2A
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50002338
(10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...)
Copy SMILES
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Affinity Data
Ki: 60nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50095890
(2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-...)
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Ki: 78nM
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Date in BDB:
2/24/2012
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Target
5-hydroxytryptamine receptor 2A
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM78433
(2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...)
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Ki: 80nM
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Date in BDB:
2/24/2012
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM81771
(CAS_3575-80-2 | NSC_15387 | MELPERONE)
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Ki: 88nM
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Date in BDB:
2/24/2012
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Target
5-hydroxytryptamine receptor 2A
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM79181
(cid_2913535 | TRIFLUOPERAZINE | SMR000059133 | MLS...)
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Ki: 135nM
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Date in BDB:
2/24/2012
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Target
5-hydroxytryptamine receptor 2A
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM81771
(CAS_3575-80-2 | NSC_15387 | MELPERONE)
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Affinity Data
Ki: 280nM
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Date in BDB:
2/24/2012
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM81771
(CAS_3575-80-2 | NSC_15387 | MELPERONE)
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Affinity Data
Ki: 410nM
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Date in BDB:
2/24/2012
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50005118
(3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-h...)
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Ki: 620nM
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Date in BDB:
2/24/2012
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50130290
(Moban | 3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,...)
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Ki: 2.40E+3nM
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Date in BDB:
2/24/2012
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Target
5-hydroxytryptamine receptor 2A
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50095890
(2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-...)
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Ki: 2.50E+3nM
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Date in BDB:
2/24/2012
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PubMed
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50026045
(CHEMBL22242 | 3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-...)
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Ki: 2.80E+3nM
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Date in BDB:
2/24/2012
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PubMed
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50095890
(2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-...)
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Affinity Data
Ki: 3.00E+3nM
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Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
5-hydroxytryptamine receptor 2A
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50026045
(CHEMBL22242 | 3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-...)
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Affinity Data
Ki: 3.10E+3nM
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
5-hydroxytryptamine receptor 2A
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50005118
(3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-h...)
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Affinity Data
Ki: 5.40E+3nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
5-hydroxytryptamine receptor 2A
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50130290
(Moban | 3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,...)
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Affinity Data
Ki: 5.80E+3nM
More data for this Ligand-Target Pair
Target Info
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Ligand Info
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ChEBI
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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