Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50006927
TargetD(2) dopamine receptor(Human)
Division of Warner Lambert

Curated by ChEMBL
LigandPNGBDBM50055721(3-{4-[2-(4-Pyridin-2-yl-piperazin-1-yl)-ethyl]-cyc...)
Affinity DataEC50:  2.80nMAssay Description:Inhibition of [3H]thymidine uptake by Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Division of Warner Lambert

Curated by ChEMBL
LigandPNGBDBM50055721(3-{4-[2-(4-Pyridin-2-yl-piperazin-1-yl)-ethyl]-cyc...)
Affinity DataKi:  2.60nMAssay Description:Binding affinity was determined in vitro on rat striatum using [3H]N-propylnorapomorphine against Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Division of Warner Lambert

Curated by ChEMBL
LigandPNGBDBM50055719(3-{4-[2-(4-Pyridin-2-yl-piperazin-1-yl)-ethyl]-cyc...)
Affinity DataKi:  8.60nMAssay Description:In vitro binding affinity for dopamine receptor D2 on rat striatal membranes by [3H]spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Division of Warner Lambert

Curated by ChEMBL
LigandPNGBDBM50055725(3-{4-[2-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-eth...)
Affinity DataKi:  8.70nMAssay Description:In vitro binding affinity for dopamine receptor D2 on rat striatal membranes by [3H]spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Division of Warner Lambert

Curated by ChEMBL
LigandPNGBDBM50002173(CHEMBL431367 | roxindole | 3-(4-(3,6-dihydro-4-phe...)
Affinity DataKi:  14nMAssay Description:In vitro binding affinity for dopamine receptor D2 on rat striatal membranes by [3H]spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Division of Warner Lambert

Curated by ChEMBL
LigandPNGBDBM50055731(3-{4-[2-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-eth...)
Affinity DataKi:  28nMAssay Description:In vitro binding affinity for dopamine receptor D2 on rat striatal membranes by [3H]spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Division of Warner Lambert

Curated by ChEMBL
LigandPNGBDBM50055721(3-{4-[2-(4-Pyridin-2-yl-piperazin-1-yl)-ethyl]-cyc...)
Affinity DataKi:  29nMAssay Description:In vitro binding affinity towards human recombinant Dopamine receptor D3 receptor expressed in CHO-K1 cells was determined using [3H]spiperone as rad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Division of Warner Lambert

Curated by ChEMBL
LigandPNGBDBM50055727(5-Methoxy-3-{4-[2-(4-pyridin-2-yl-piperazin-1-yl)-...)
Affinity DataKi:  29nMAssay Description:In vitro binding affinity for dopamine receptor D2 on rat striatal membranes by [3H]spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Division of Warner Lambert

Curated by ChEMBL
LigandPNGBDBM50055721(3-{4-[2-(4-Pyridin-2-yl-piperazin-1-yl)-ethyl]-cyc...)
Affinity DataKi:  50nMAssay Description:In vitro binding affinity for dopamine receptor D2 on rat striatal membranes by [3H]spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Division of Warner Lambert

Curated by ChEMBL
LigandPNGBDBM50055721(3-{4-[2-(4-Pyridin-2-yl-piperazin-1-yl)-ethyl]-cyc...)
Affinity DataKi:  73nMAssay Description:In vitro binding affinity towards human recombinant Dopamine receptor D4 expressed in CHO-K1 cells was determined using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Division of Warner Lambert

Curated by ChEMBL
LigandPNGBDBM50055728(1-Methyl-3-{4-[2-(4-pyridin-2-yl-piperazin-1-yl)-e...)
Affinity DataKi:  83nMAssay Description:In vitro binding affinity for dopamine receptor D2 on rat striatal membranes by [3H]spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Division of Warner Lambert

Curated by ChEMBL
LigandPNGBDBM50055723(3-[4-(4-Pyridin-2-yl-piperazin-1-ylmethyl)-cyclohe...)
Affinity DataKi:  85nMAssay Description:In vitro binding affinity for dopamine receptor D2 on rat striatal membranes by [3H]spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Division of Warner Lambert

Curated by ChEMBL
LigandPNGBDBM50055734(5-Fluoro-3-{4-[2-(4-pyridin-2-yl-piperazin-1-yl)-e...)
Affinity DataKi:  110nMAssay Description:In vitro binding affinity for dopamine receptor D2 on rat striatal membranes by [3H]spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Division of Warner Lambert

Curated by ChEMBL
LigandPNGBDBM50055720(3-[4-(4-Pyridin-2-yl-piperazin-1-ylmethyl)-cyclohe...)
Affinity DataKi:  122nMAssay Description:In vitro binding affinity for dopamine receptor D2 on rat striatal membranes by [3H]spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Division of Warner Lambert

Curated by ChEMBL
LigandPNGBDBM50055729(3-{4-[2-(4-Phenyl-piperazin-1-yl)-ethyl]-cyclohexy...)
Affinity DataKi:  124nMAssay Description:In vitro binding affinity for dopamine receptor D2 on rat striatal membranes by [3H]spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Division of Warner Lambert

Curated by ChEMBL
LigandPNGBDBM50055733(3-{4-[2-(4-Pyridin-2-yl-piperazin-1-yl)-ethyl]-cyc...)
Affinity DataKi:  139nMAssay Description:In vitro binding affinity for dopamine receptor D2 on rat striatal membranes by [3H]spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Division of Warner Lambert

Curated by ChEMBL
LigandPNGBDBM50055722(3-{4-[2-(4-Pyrimidin-2-yl-piperazin-1-yl)-ethyl]-c...)
Affinity DataKi:  161nMAssay Description:In vitro binding affinity for dopamine receptor D2 on rat striatal membranes by [3H]spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Division of Warner Lambert

Curated by ChEMBL
LigandPNGBDBM50055735(3-{4-[2-(4-Pyridin-2-yl-piperazin-1-yl)-ethyl]-cyc...)
Affinity DataKi:  270nMAssay Description:In vitro binding affinity for dopamine receptor D2 on rat striatal membranes by [3H]spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Division of Warner Lambert

Curated by ChEMBL
LigandPNGBDBM50055724(PD-137789 | 1-[2-((S)-4-Phenyl-cyclohex-3-enyl)-et...)
Affinity DataKi:  412nMAssay Description:In vitro binding affinity for dopamine receptor D2 on rat striatal membranes by [3H]spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Division of Warner Lambert

Curated by ChEMBL
LigandPNGBDBM50055726(3-[4-(4-Pyridin-2-yl-piperazin-1-yl)-cyclohexyl]-1...)
Affinity DataKi:  457nMAssay Description:In vitro binding affinity for dopamine receptor D2 on rat striatal membranes by [3H]spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Division of Warner Lambert

Curated by ChEMBL
LigandPNGBDBM50055730(3-{4-[2-(4-Thiophen-2-yl-3,6-dihydro-2H-pyridin-1-...)
Affinity DataKi:  630nMAssay Description:In vitro binding affinity for dopamine receptor D2 on rat striatal membranes by [3H]spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Division of Warner Lambert

Curated by ChEMBL
LigandPNGBDBM50055732(3-(4-{2-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-ethyl...)
Affinity DataKi:  645nMAssay Description:In vitro binding affinity for dopamine receptor D2 on rat striatal membranes by [3H]spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Division of Warner Lambert

Curated by ChEMBL
LigandPNGBDBM50055718(3-[4-(4-Pyridin-2-yl-piperazin-1-yl)-cyclohexyl]-1...)
Affinity DataKi:  2.60E+3nMAssay Description:In vitro binding affinity for dopamine receptor D2 on rat striatal membranes by [3H]spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed