Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50006876
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Pig)
Wayne State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054838BDBM50054838(3-(4-Tridec-2-ynyloxymethyl-phenyl)-propionic acid...)
Affinity DataIC50: 35nMAssay Description:Inhibitory activity against conversion of [1-14C]arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Pig)
Wayne State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054833BDBM50054833(3-{4-[((E)-Tridec-2-enyl)oxymethyl]-phenyl}-propio...)
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against conversion of [1-14C]arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Pig)
Wayne State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054836BDBM50054836((4-Tridec-2-ynyloxymethyl-phenyl)-acetic acid | CH...)
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against conversion of [1-14C]arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Pig)
Wayne State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054851BDBM50054851(4-Tridec-2-ynyloxymethyl-benzoic acid | CHEMBL1422...)
Affinity DataIC50: 60nMAssay Description:Inhibitory activity against conversion of [1-14C]arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Pig)
Wayne State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054840BDBM50054840(3-(4-Undec-2-ynyloxymethyl-phenyl)-propionic acid ...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against conversion of [1-14C]arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Pig)
Wayne State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054844BDBM50054844(3-(4-Tetradeca-2,3-dienyloxymethyl-phenyl)-propion...)
Affinity DataIC50: 280nMAssay Description:Inhibitory activity against conversion of [1-14C]arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Pig)
Wayne State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054832BDBM50054832(3-(3-Tridec-2-ynyloxymethyl-phenyl)-propionic acid...)
Affinity DataIC50: 320nMAssay Description:Inhibitory activity against conversion of [1-14C]arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Pig)
Wayne State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054846BDBM50054846(3-(4-Pentadec-2-ynyloxymethyl-phenyl)-propionic ac...)
Affinity DataIC50: 320nMAssay Description:Inhibitory activity against conversion of [1-14C]arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Pig)
Wayne State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054849BDBM50054849(3-(4-Non-2-ynyloxymethyl-phenyl)-propionic acid | ...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against conversion of [1-14C]arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Pig)
Wayne State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054850BDBM50054850(3-{4-[((Z)-Tridec-2-enyl)oxymethyl]-phenyl}-propio...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibitory activity against conversion of [1-14C]arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Pig)
Wayne State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50407987BDBM50407987(CHEMBL2112001)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity against conversion of [1-14C]arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Pig)
Wayne State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054841BDBM50054841(3-[4-(7-Phenyl-hept-2-ynyloxymethyl)-phenyl]-propi...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity against conversion of [1-14C]arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Pig)
Wayne State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054835BDBM50054835(4-Dec-2-ynyloxymethyl-benzoic acid | CHEMBL359394)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory activity against conversion of [1-14C]arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Pig)
Wayne State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054847BDBM50054847(4-Heptadec-2-ynyloxymethyl-benzoic acid | CHEMBL14...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against conversion of [1-14C]arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Pig)
Wayne State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054848BDBM50054848(3-(3-Non-3-ynyloxymethyl-phenyl)-propionic acid | ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against conversion of [1-14C]arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Pig)
Wayne State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054839BDBM50054839(3-(4-Heptadec-2-ynyloxymethyl-phenyl)-propionic ac...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against conversion of [1-14C]arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Pig)
Wayne State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054845BDBM50054845(4-(4-Tridec-2-ynyloxymethyl-phenyl)-butyric acid |...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against conversion of [1-14C]arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Pig)
Wayne State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054843BDBM50054843(3-(3-Undec-2-ynylsulfanylmethyl-phenyl)-propionic ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against conversion of [1-14C]arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Pig)
Wayne State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054834BDBM50054834(3-(4-Tridecyloxymethyl-phenyl)-propionic acid | CH...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against conversion of [1-14C]arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Pig)
Wayne State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054842BDBM50054842(3-(3-Non-2-ynyloxymethyl-phenyl)-propionic acid | ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against conversion of [1-14C]arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Pig)
Wayne State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054837BDBM50054837(3-(3-Undec-2-ynyloxymethyl-phenyl)-propionic acid ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against conversion of [1-14C]arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed