Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50006857
Target5-hydroxytryptamine receptor 1A(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054718(3-Amino-thiophene-2-carboxylic acid [4-(4-benzo[d]...)
Affinity DataIC50: 1.30nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054710(1,2,3,4-Tetrahydro-quinoline-8-carboxylic acid [4-...)
Affinity DataIC50: 1.90nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054713(2-Amino-thiophene-3-carboxylic acid [4-(4-benzo[d]...)
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054716(1H-Indazole-3-carboxylic acid [4-(4-benzo[d]isothi...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of mouse Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054706(1H-Indole-7-carboxylic acid [4-(4-benzo[d]isothiaz...)
Affinity DataIC50: 2.70nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054707(Pyridine-2-carboxylic acid [4-(4-benzo[d]isothiazo...)
Affinity DataIC50: 2.80nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054705(2-Amino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-...)
Affinity DataIC50: 3.30nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054715(4-Amino-thiophene-3-carboxylic acid [4-(4-benzo[d]...)
Affinity DataIC50: 3.5nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054716(1H-Indazole-3-carboxylic acid [4-(4-benzo[d]isothi...)
Affinity DataIC50: 3.60nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054714(3-Amino-pyridine-2-carboxylic acid [4-(4-benzo[d]i...)
Affinity DataIC50: 3.80nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054712(3H-Benzoimidazole-4-carboxylic acid [4-(4-benzo[d]...)
Affinity DataIC50: 4.20nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054703(Quinoline-8-carboxylic acid [4-(4-benzo[d]isothiaz...)
Affinity DataIC50: 4.30nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054704(2,3-Dihydro-1H-indole-7-carboxylic acid [4-(4-benz...)
Affinity DataIC50: 4.30nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054711(4-Amino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-...)
Affinity DataIC50: 4.70nMAssay Description:Inhibitory activity against Dopamine receptor D2 from miceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054719(N-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 4.90nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054711(4-Amino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-...)
Affinity DataIC50: 5.10nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054702(3-Amino-benzo[b]thiophene-2-carboxylic acid [4-(4-...)
Affinity DataIC50: 5.80nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054708(1H-Indole-3-carboxylic acid [4-(4-benzo[d]isothiaz...)
Affinity DataIC50: 5.80nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054702(3-Amino-benzo[b]thiophene-2-carboxylic acid [4-(4-...)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of mouse Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054715(4-Amino-thiophene-3-carboxylic acid [4-(4-benzo[d]...)
Affinity DataIC50: 6nMAssay Description:Inhibition of mouse Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054709(N-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 6.60nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054717(3-Amino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-...)
Affinity DataIC50: 7nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054712(3H-Benzoimidazole-4-carboxylic acid [4-(4-benzo[d]...)
Affinity DataIC50: 7.60nMAssay Description:Inhibitory activity against Dopamine receptor D2 from miceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054705(2-Amino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-...)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of mouse Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054718(3-Amino-thiophene-2-carboxylic acid [4-(4-benzo[d]...)
Affinity DataIC50: 9.60nMAssay Description:Inhibition of mouse Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054713(2-Amino-thiophene-3-carboxylic acid [4-(4-benzo[d]...)
Affinity DataIC50: 11nMAssay Description:Inhibitory activity against Dopamine receptor D2 from miceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054708(1H-Indole-3-carboxylic acid [4-(4-benzo[d]isothiaz...)
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against Dopamine receptor D2 from miceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054703(Quinoline-8-carboxylic acid [4-(4-benzo[d]isothiaz...)
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against Dopamine receptor D2 from miceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054717(3-Amino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-...)
Affinity DataIC50: 16nMAssay Description:Inhibitory activity against Dopamine receptor D2 from miceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50001885(3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
Affinity DataIC50: 23nMAssay Description:Inhibition of mouse Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054707(Pyridine-2-carboxylic acid [4-(4-benzo[d]isothiazo...)
Affinity DataIC50: 24nMAssay Description:Inhibition of mouse Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054714(3-Amino-pyridine-2-carboxylic acid [4-(4-benzo[d]i...)
Affinity DataIC50: 24nMAssay Description:Inhibitory activity against Dopamine receptor D2 from miceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054709(N-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 25nMAssay Description:Inhibitory activity against Dopamine receptor D2 from miceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054710(1,2,3,4-Tetrahydro-quinoline-8-carboxylic acid [4-...)
Affinity DataIC50: 28nMAssay Description:Inhibition of mouse Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054706(1H-Indole-7-carboxylic acid [4-(4-benzo[d]isothiaz...)
Affinity DataIC50: 28nMAssay Description:Inhibition of mouse Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054704(2,3-Dihydro-1H-indole-7-carboxylic acid [4-(4-benz...)
Affinity DataIC50: 34nMAssay Description:Inhibition of mouse Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50054719(N-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 47nMAssay Description:Inhibition of mouse Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataIC50: 290nMAssay Description:Inhibition of mouse Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50001885(3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
Affinity DataIC50: 430nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Mouse)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed