Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50006817
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054245(CHEMBL45281 | cid_176157 | 5-Chloro-N-cyclopropylm...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of [125I]CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 dosesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054252(5-Bromo-N-cyclopropylmethyl-2-methyl-N-propyl-N'-(...)
Affinity DataKi:  2nMAssay Description:Inhibition of [125I]CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 dosesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054250(N-Cyclopropylmethyl-2,5-dimethyl-N-propyl-N'-(2,4,...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of [125I]CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 dosesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054248(2,5-Dimethyl-N,N-dipropyl-N'-(2,4,6-trichloro-phen...)
Affinity DataKi:  2.5nMAssay Description:Inhibition of [125I]CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 dosesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054253(N-Cyclopropylmethyl-5-ethyl-2-methyl-N-propyl-N'-(...)
Affinity DataKi:  3.80nMAssay Description:Inhibition of [125I]CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 dosesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054246(N-Cyclopropylmethyl-2-methyl-N-propyl-N'-(2,4,6-tr...)
Affinity DataKi:  30nMAssay Description:Inhibition of [125I]CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 dosesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054225(N-Cyclopropylmethyl-6-methyl-N-propyl-N'-(2,4,6-tr...)
Affinity DataKi:  57nMAssay Description:Inhibition of [125I]CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 dosesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054249(N*4*-Cyclopropylmethyl-6-methyl-N*4*-propyl-N*2*-(...)
Affinity DataKi:  70nMAssay Description:Inhibition of [125I]CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 dosesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054247(N-Cyclopropylmethyl-2,5,N'-trimethyl-N-propyl-N'-(...)
Affinity DataKi:  150nMAssay Description:Inhibition of [125I]CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 dosesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054244(N-Cyclopropylmethyl-2-methyl-N-propyl-N'-(2,4,5-tr...)
Affinity DataKi:  253nMAssay Description:Inhibition of [125I]CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 dosesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054255(N-Cyclopropylmethyl-2-methyl-N-propyl-N'-(2,4,6-tr...)
Affinity DataKi:  1.39E+3nMAssay Description:Inhibition of [125I]CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 dosesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054251(N*2*-Cyclopropylmethyl-6-methyl-N*2*-propyl-N*4*-(...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125I]CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 dosesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50054254(N-Cyclopropylmethyl-N-propyl-N'-(2,4,6-trichloro-p...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125I]CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 dosesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed