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Found
52
Enz. Inhib. hit(s) with all data for entry = 5055
Target
Sodium-dependent serotonin transporter
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM82217
([4-(3,4-Dichloro-phenyl)-1,2,3,4-tetrahydro-naphth...)
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Affinity Data
Ki: 0.0400nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
Sodium-dependent serotonin transporter
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM77970
(CLOMIPRAMINE HYDROCHLORIDE | CHLORIMIPRAMINE | 3-(...)
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Affinity Data
Ki: 0.140nM
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
5-hydroxytryptamine receptor 2C
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM35256
(MIANSERIN (+) | MIANSERIN | Lerivon | Tolvon | MIA...)
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Affinity Data
Ki: 0.400nM
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Date in BDB:
2/24/2012
Entry Details
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PubMed
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Target
Sodium-dependent serotonin transporter
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM25870
(CITALOPRAM HYDROBROMIDE | [3H]Escitalopram | Escit...)
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Affinity Data
Ki: 0.650nM
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Date in BDB:
2/24/2012
Entry Details
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PubMed
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Target
5-hydroxytryptamine receptor 2A
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM35256
(MIANSERIN (+) | MIANSERIN | Lerivon | Tolvon | MIA...)
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Affinity Data
Ki: 1nM
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In Depth
Date in BDB:
2/24/2012
Entry Details
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PubMed
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Target
5-hydroxytryptamine receptor 2A
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM22870
(CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...)
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Affinity Data
Ki: 1nM
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Date in BDB:
2/24/2012
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Target
Sodium-dependent serotonin transporter
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM30130
(Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...)
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Affinity Data
Ki: 1.96nM
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Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
5-hydroxytryptamine receptor 2C
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM22870
(CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...)
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Affinity Data
Ki: 2nM
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Date in BDB:
2/24/2012
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PubMed
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Target
Sodium-dependent serotonin transporter
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM50254790
(NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine)
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Affinity Data
Ki: 3.15nM
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Date in BDB:
2/24/2012
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PubMed
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Target
5-hydroxytryptamine receptor 2C
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM50020712
(CHEMBL629 | Amitriptylin | 10,11-dihydro-N,N-dimet...)
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Affinity Data
Ki: 4.30nM
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Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
5-hydroxytryptamine receptor 2A
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM50020712
(CHEMBL629 | Amitriptylin | 10,11-dihydro-N,N-dimet...)
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Affinity Data
Ki: 4.30nM
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Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
5-hydroxytryptamine receptor 2A
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM112777
(NORTRIPTYLINE | US8629135, SW-02)
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Affinity Data
Ki: 5nM
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Date in BDB:
2/24/2012
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Article
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PubMed
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Target
5-hydroxytryptamine receptor 2A
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM50073444
(2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}[1,2...)
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Affinity Data
Ki: 6nM
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Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
5-hydroxytryptamine receptor 2C
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM112777
(NORTRIPTYLINE | US8629135, SW-02)
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Affinity Data
Ki: 8.5nM
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
5-hydroxytryptamine receptor 2C
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM50079527
(CHEMBL101740 | cis-doxepin | DOXEPIN | (3E)-3-dibe...)
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Affinity Data
Ki: 8.80nM
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
Sodium-dependent serotonin transporter
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM50010859
(CHEMBL11 | Imipramin | IMIPRAMINE HYDROCHLORIDE | ...)
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Affinity Data
Ki: 14.2nM
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Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
PDB
3D Structure (crystal)
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Target
5-hydroxytryptamine receptor 2A
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM77970
(CLOMIPRAMINE HYDROCHLORIDE | CHLORIMIPRAMINE | 3-(...)
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Affinity Data
Ki: 15nM
More data for this Ligand-Target Pair
Target Info
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
5-hydroxytryptamine receptor 2C
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM77970
(CLOMIPRAMINE HYDROCHLORIDE | CHLORIMIPRAMINE | 3-(...)
Copy SMILES
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Affinity Data
Ki: 22nM
More data for this Ligand-Target Pair
Target Info
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Date in BDB:
2/24/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
5-hydroxytryptamine receptor 2A
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM50079527
(CHEMBL101740 | cis-doxepin | DOXEPIN | (3E)-3-dibe...)
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Affinity Data
Ki: 26nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
5-hydroxytryptamine receptor 2C
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM30130
(Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...)
Copy SMILES
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Affinity Data
Ki: 42.6nM
More data for this Ligand-Target Pair
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Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
5-hydroxytryptamine receptor 2A
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM35228
(Ludiomil | CHEMBL21731 | Dibencycladine | maprotil...)
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Affinity Data
Ki: 51nM
More data for this Ligand-Target Pair
Target Info
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Sodium-dependent serotonin transporter
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM112777
(NORTRIPTYLINE | US8629135, SW-02)
Copy SMILES
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Affinity Data
Ki: 60.8nM
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In Depth
Date in BDB:
2/24/2012
Entry Details
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PubMed
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Target
Sodium-dependent serotonin transporter
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM50020706
(cis -[3-(4-Bromo-phenyl)-3-pyridin-3-yl-allyl]-dim...)
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Affinity Data
Ki: 67.6nM
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ChEBI
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
5-hydroxytryptamine receptor 2C
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM50010859
(CHEMBL11 | Imipramin | IMIPRAMINE HYDROCHLORIDE | ...)
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Affinity Data
Ki: 94nM
More data for this Ligand-Target Pair
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Date in BDB:
2/24/2012
Entry Details
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PubMed
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Target
5-hydroxytryptamine receptor 2A
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM35229
(Desmethylimipramine | 3-(10,11-dihydro-5H-dibenzo[...)
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Affinity Data
Ki: 121nM
More data for this Ligand-Target Pair
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
5-hydroxytryptamine receptor 2C
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM35228
(Ludiomil | CHEMBL21731 | Dibencycladine | maprotil...)
Copy SMILES
Affinity Data
Ki: 122nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Sodium-dependent serotonin transporter
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM50079527
(CHEMBL101740 | cis-doxepin | DOXEPIN | (3E)-3-dibe...)
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Affinity Data
Ki: 126nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Sodium-dependent serotonin transporter
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM35229
(Desmethylimipramine | 3-(10,11-dihydro-5H-dibenzo[...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 152nM
More data for this Ligand-Target Pair
Target Info
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
5-hydroxytryptamine receptor 2C
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM50254790
(NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine)
Copy SMILES
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Affinity Data
Ki: 157nM
More data for this Ligand-Target Pair
Target Info
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
5-hydroxytryptamine receptor 2A
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM50010859
(CHEMBL11 | Imipramin | IMIPRAMINE HYDROCHLORIDE | ...)
Copy SMILES
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Affinity Data
Ki: 160nM
More data for this Ligand-Target Pair
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
5-hydroxytryptamine receptor 2C
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM50073444
(2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}[1,2...)
Copy SMILES
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Affinity Data
Ki: 193nM
More data for this Ligand-Target Pair
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In Depth
Date in BDB:
2/24/2012
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PubMed
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Target
5-hydroxytryptamine receptor 2C
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM81448
(CAS_5560-72-5 | NSC_21722 | IPRINDOLE)
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Affinity Data
Ki: 206nM
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In Depth
Date in BDB:
2/24/2012
Entry Details
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PubMed
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Target
5-hydroxytryptamine receptor 2A
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM81448
(CAS_5560-72-5 | NSC_21722 | IPRINDOLE)
Copy SMILES
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Affinity Data
Ki: 217nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Sodium-dependent serotonin transporter
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM50073444
(2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}[1,2...)
Copy SMILES
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Affinity Data
Ki: 243nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
5-hydroxytryptamine receptor 2C
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM35229
(Desmethylimipramine | 3-(10,11-dihydro-5H-dibenzo[...)
Copy SMILES
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Affinity Data
Ki: 244nM
More data for this Ligand-Target Pair
Target Info
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
5-hydroxytryptamine receptor 2C
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM25870
(CITALOPRAM HYDROBROMIDE | [3H]Escitalopram | Escit...)
Copy SMILES
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Affinity Data
Ki: 269nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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Similars
In Depth
Date in BDB:
2/24/2012
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Sodium-dependent serotonin transporter
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM22870
(CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...)
Copy SMILES
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Affinity Data
Ki: 290nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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In Depth
Date in BDB:
2/24/2012
Entry Details
Article
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Target
5-hydroxytryptamine receptor 2A
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM30130
(Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...)
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Ki: 708nM
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Date in BDB:
2/24/2012
Entry Details
Article
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Target
5-hydroxytryptamine receptor 2C
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM50005548
((+/-)-2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquin...)
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Ki: 1.00E+3nM
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Date in BDB:
2/24/2012
Entry Details
Article
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Target
5-hydroxytryptamine receptor 2C
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM82217
([4-(3,4-Dichloro-phenyl)-1,2,3,4-tetrahydro-naphth...)
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Ki: 1.00E+3nM
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Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
5-hydroxytryptamine receptor 2C
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM50020706
(cis -[3-(4-Bromo-phenyl)-3-pyridin-3-yl-allyl]-dim...)
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Ki: 1.00E+3nM
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Date in BDB:
2/24/2012
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Article
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PubMed
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Target
5-hydroxytryptamine receptor 2C
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM15581
(US8633208, Clorgyline | [3-(2,4-dichlorophenoxy)pr...)
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Ki: 1.00E+3nM
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Date in BDB:
2/24/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
5-hydroxytryptamine receptor 2C
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM15581
(US8633208, Clorgyline | [3-(2,4-dichlorophenoxy)pr...)
Copy SMILES
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Affinity Data
Ki: 1.00E+3nM
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Date in BDB:
2/24/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
5-hydroxytryptamine receptor 2A
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM50020706
(cis -[3-(4-Bromo-phenyl)-3-pyridin-3-yl-allyl]-dim...)
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Affinity Data
Ki: 1.00E+3nM
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Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
5-hydroxytryptamine receptor 2A
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM82217
([4-(3,4-Dichloro-phenyl)-1,2,3,4-tetrahydro-naphth...)
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Ki: 1.00E+3nM
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Date in BDB:
2/24/2012
Entry Details
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Target
5-hydroxytryptamine receptor 2A
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM50254790
(NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine)
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Ki: 1.00E+3nM
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Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
5-hydroxytryptamine receptor 2A
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM50005548
((+/-)-2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquin...)
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Ki: 1.00E+3nM
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Date in BDB:
2/24/2012
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PubMed
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Target
5-hydroxytryptamine receptor 2A
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM25870
(CITALOPRAM HYDROBROMIDE | [3H]Escitalopram | Escit...)
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Ki: 1.00E+3nM
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Date in BDB:
2/24/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Sodium-dependent serotonin transporter
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM50005548
((+/-)-2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquin...)
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Affinity Data
Ki: 1.00E+3nM
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Date in BDB:
2/24/2012
Entry Details
Article
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PubMed
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Target
Sodium-dependent serotonin transporter
(Rat)
University of Turku
Curated by
PDSP K
i
Database
Ligand
BDBM35256
(MIANSERIN (+) | MIANSERIN | Lerivon | Tolvon | MIA...)
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Ki: 1.00E+3nM
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Date in BDB:
2/24/2012
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