Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50036451
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50053432(2-(4-Methylsulfanyl-phenyl)-3-pyridin-4-yl-6,7-dih...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory concentration against 5-lipoxygenase in rat RBL-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibitory concentration against 5-lipoxygenase in rat RBL-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14832(4-[6-(4-fluorophenyl)-2H,3H-imidazo[2,1-b][1,3]thi...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibitory concentration against Prostaglandin H2 synthase 1 (PGHS-1) from ram seminal vesicleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14832(4-[6-(4-fluorophenyl)-2H,3H-imidazo[2,1-b][1,3]thi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against 5-lipoxygenase in rat RBL-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50053430(4-[3-Cyclopropyl-5-(4-fluoro-phenyl)-3H-imidazol-4...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibitory concentration against Prostaglandin H2 synthase 1 (PGHS-1) from ram seminal vesicleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50339185((2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid | ...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibitory concentration against Prostaglandin H2 synthase 1 (PGHS-1) from ram seminal vesicleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM15237(SB2 | CHEMBL96741 | 4-[1-(cyclopropylmethyl)-4-(4-...)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibitory concentration against Prostaglandin H2 synthase 1 (PGHS-1) from ram seminal vesicleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50053430(4-[3-Cyclopropyl-5-(4-fluoro-phenyl)-3H-imidazol-4...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibitory concentration against 5-lipoxygenase in rat RBL-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50053424(SB-210313 | 4-{3-[4-(4-Fluoro-phenyl)-5-pyridin-4-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against Prostaglandin H2 synthase 1 (PGHS-1) from ram seminal vesicleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50053410(4-(4-Fluorophenyl)-5-(pyridin-4-yl)-1H-imidazole |...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against Prostaglandin H2 synthase 1 (PGHS-1) from ram seminal vesicleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50053432(2-(4-Methylsulfanyl-phenyl)-3-pyridin-4-yl-6,7-dih...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against Prostaglandin H2 synthase 1 (PGHS-1) from ram seminal vesicleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50053412(4-{3-[4-(3,4-Dichloro-phenyl)-5-pyridin-4-yl-imida...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against Prostaglandin H2 synthase 1 (PGHS-1) from ram seminal vesicleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50053412(4-{3-[4-(3,4-Dichloro-phenyl)-5-pyridin-4-yl-imida...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against 5-lipoxygenase in rat RBL-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50053410(4-(4-Fluorophenyl)-5-(pyridin-4-yl)-1H-imidazole |...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against 5-lipoxygenase in rat RBL-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50053424(SB-210313 | 4-{3-[4-(4-Fluoro-phenyl)-5-pyridin-4-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against 5-lipoxygenase in rat RBL-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM15237(SB2 | CHEMBL96741 | 4-[1-(cyclopropylmethyl)-4-(4-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against 5-lipoxygenase in rat RBL-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed